4',7-Dihydroxy-5,6,8-trimethoxyflavone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 4',7-Dihydroxy-5,6,8-trimethoxyflavone
• 英文别名: 7-hydroxy-2-(4-hydroxyphenyl)-5,6,8-trimethoxychromen-4-one
• 化学式: C₁₈H₁₆O₇
• 分子量: 344.3
• InChiKey: NHZSAXLFDHXJQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• [EN] COMPOSITION CONTAINING FLAVONOIDS FOR TREATMENT BRAIN DISORDERS<br/>[FR] COMPOSITIONS CONTENANT DES FLAVONOIDES POUR LE TRAITEMENT DE TROUBLES CEREBRAUX
  申请人：IMPERIAL COLLEGE

  公开号：WO2002053152A1

  公开（公告）日：2002-07-11

  The present invention relates to a pharmaceutical composition for use (or when in use) in the treatment of brain disorders, said composition comprising one or more flavonoids admixed with a pharmaceutically acceptable diluent, excipient or carrier. The invention also relates to a process for the preparation of said pharmaceutical composition. A further aspect of the invention relates to the use of one or more flavonoids in the preparation of a medicament for treating brain disorders, and to a method of treating a brain disorder, said method comprising administering to a subject in need of treatment a therapeutically effective amount of one or more flavonoids.