8-C-Methylkaempferol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 8-C-Methylkaempferol
• 英文别名: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-methylchromen-4-one
• 化学式: C₁₆H₁₂O₆
• 分子量: 300.26
• InChiKey: QWFMXOMZDHXFLG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Compositions and methods of use
  申请人：Melcare Medical Pty Ltd

  公开号：US11154578B2

  公开（公告）日：2021-10-26

  The present invention provides a composition comprising honey, a preservative and an aqueous carrier, wherein the honey is present in an amount in the range of from 2 to 50% w/w. Uses of the compositions of the invention for the management, treatment or prevention of a respiratory, ophthalmic, ear or vaginal condition in a subject, and for wound management are also described.

  本发明提供了一种包含蜂蜜、防腐剂和水性载体的组合物，其中蜂蜜的含量范围为 2% 至 50% w/w。本发明的组合物还可用于控制、治疗或预防受试者的呼吸道、眼科、耳科或阴道疾病，以及用于伤口处理。
• Oral compositions and use thereof
  申请人：——

  公开号：US20040057908A1

  公开（公告）日：2004-03-25

  The present invention relates to an oral composition which includes an organoleptically suitable carrier and an amount of a terpenoid and a flavonoid, dispersed in the carrier, which is effective to prevent or treat dental caries, dental plaque formation, gingivitis, candidiasis, dental stomatitis, aphthous ulceration, or fungal infection. The invention also relates to various uses of oral compositions, containing a terpenoid, a flavonoid, or both, such uses include: inhibiting the activity of surface-bound glusosyltransferase; treating or inhibiting dental caries, gingivitis, candidiasis, denture stomatitis; inhibiting the accumulation of microorganisms on an oral surface; and/or treating or inhibiting aphthous ulcerations on an oral surface.

  本发明涉及一种口服组合物，该组合物包括一种有机性适宜的载体以及一定量的萜类化合物和黄酮类化合物，它们分散在载体中，可有效预防或治疗龋齿、牙菌斑形成、牙龈炎、念珠菌病、牙齿口腔炎、口腔溃疡或真菌感染。本发明还涉及含有萜类化合物、类黄酮或两者的口服组合物的各种用途，这些用途包括：抑制表面结合的葡糖基转移酶的活性；治疗或抑制龋齿、牙龈炎、念珠菌病、义齿口腔炎；抑制微生物在口腔表面的积聚；和/或治疗或抑制口腔表面的阿弗他溃疡。
• ORAL COMPOSITIONS AND USE THEREOF
  申请人：University of Rochester

  公开号：EP1399119A2

  公开（公告）日：2004-03-24
• FLAVONOIDDERIVAT ZUR BEHANDLUNG VON ZAHNKARIES
  申请人：Mühlbauer Technology GmbH

  公开号：EP4017585A1

  公开（公告）日：2022-06-29
• COMPOSITIONS AND METHODS OF USE
  申请人：Melcare Medical Pty Ltd

  公开号：US20170209500A1

  公开（公告）日：2017-07-27

  The present invention provides a composition comprising honey, a preservative and an aqueous carrier, wherein the honey is present in an amount in the range of from 2 to 50% w/w. Uses of the compositions of the invention for the management, treatment or prevention of a respiratory, ophthalmic, ear or vaginal condition in a subject, and for wound management are also described.