2-butyl-4,5-dimethyloxazole | 84027-97-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-butyl-4,5-dimethyloxazole
• 英文别名: 2-Butyl-4,5-dimethyl-oxazol；2-butyl-4,5-dimethyl-1,3-oxazole
• CAS: 84027-97-4
• 化学式: C₉H₁₅NO
• 分子量: 153.224
• InChiKey: VAGMYBQNOAXNOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Cosmetic composition comprising white rose flower extract for skin whitening and improving skin wrinkle
  申请人：CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

  公开号：US10842727B2

  公开（公告）日：2020-11-24

  Provided is a functional cosmetic composition of white rose extract and a gartanin derivative compound isolated therefrom, and specifically, to a cosmetic composition for skin whitening and skin wrinkle alleviation containing, as active ingredients, white rose petal extract and gartanin derivative compounds isolated therefrom. The white rose extract and gartanin derivative compound, according to the present invention, are safe without causing side effects on the skin, prevent melanin production through a mechanism inhibiting tyrosinase activity, thereby having a whitening effect, and exhibit a wrinkle alleviation effect by a mechanism inhibiting MMP-1 activity, and thus the composition, of the present invention, containing the same as active ingredients, can be utilized as a material for functional cosmetics for skin whitening and wrinkle alleviation without causing skin irritation.

  本发明提供了一种由白玫瑰提取物和从中分离出的一种水苏糖苷衍生物化合物组成的功能性化妆品组合物，特别是一种用于美白和减轻皮肤皱纹的化妆品组合物，其活性成分包含白玫瑰花瓣提取物和从中分离出的水苏糖苷衍生物化合物。根据本发明，白玫瑰提取物和水苏碱衍生物化合物是安全的，不会对皮肤产生副作用，通过抑制酪氨酸酶活性的机制防止黑色素生成，从而具有美白效果，并通过抑制 MMP-1 活性的机制表现出抗皱效果，因此，本发明的组合物中含有相同的活性成分，可用作皮肤美白和抗皱功能性化妆品的材料，而不会对皮肤产生刺激。
• INHIBITORS OF FATTY ACID AMIDE HYDROLASE
  申请人：THE SCRIPPS RESEARCH INSTITUTE

  公开号：EP1549624B1

  公开（公告）日：2009-05-13
• COSMETIC COMPOSITION COMPRISING WHITE ROSE FLOWER EXTRACT FOR SKIN WHITENING AND IMPROVING SKIN WRINKLE
  申请人：CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

  公开号：US20170042795A1

  公开（公告）日：2017-02-16

  Provided is a functional cosmetic composition of white rose extract and a gartanin derivative compound isolated therefrom, and specifically, to a cosmetic composition for skin whitening and skin wrinkle alleviation containing, as active ingredients, white rose petal extract and gartanin derivative compounds isolated therefrom. The white rose extract and gartanin derivative compound, according to the present invention, are safe without causing side effects on the skin, prevent melanin production through a mechanism inhibiting tyrosinase activity, thereby having a whitening effect, and exhibit a wrinkle alleviation effect by a mechanism inhibiting MMP-1 activity, and thus the composition, of the present invention, containing the same as active ingredients, can be utilized as a material for functional cosmetics for skin whitening and wrinkle alleviation without causing skin irritation.

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