2-hexenoic acid allyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-hexenoic acid allyl ester
• 英文别名: hexenoic acid allyl ester；allyl 2-hexenoate；allyl hexenoate；Prop-2-enyl hex-2-enoate；prop-2-enyl hex-2-enoate
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: VOLVXFXDLNXTMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  diethylzinc 、 (E)-4-(Diethoxy-phosphoryloxy)-but-2-enoic acid allyl ester 在 copper(I) trifluoromethanesulfonate benzene 、 C₂₆H₄₁N₃O₄ 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 生成 2-hexenoic acid allyl ester 、 allyl (S)-2-ethylbut-3-enoate 、 allyl (R)-2-ethylbut-3-enoate
  参考文献：
  名称：

  Enantioselective Synthesis of α-Alkyl-β,γ-unsaturated Esters through Efficient Cu-Catalyzed Allylic Alkylations

  摘要：

  A method for enantioselective Cu-catalyzed allylic substitution between various alkylzincs and alpha,beta-unsaturated carboxylic esters that bear a gamma-phosphate is reported. These transformations afford alpha-alkyl-beta,gamma-unsaturated carbonyls with regioselectivities of 7:1 to >20:1 (S(N)2':S(N)2) and in 87-97% ee. The utility of the method is illustrated by a convergent total synthesis of topoisomerse II inhibitor (R)-elenic acid.

  DOI：

  10.1021/ja0300618

文献信息

• Polymer compositions comprising telomers and articles or parts using these compositions
  申请人：——

  公开号：US20040097625A1

  公开（公告）日：2004-05-20

  Composition comprising one or more polymers and one or more substances selected from telomers having a number average degree of telomerization of less than or equal to 8.0 (substances A) and optionally from substances such as diesters of phthalic acid or diesters of saturated aliphatic &agr;,&ohgr;-dicarboxylic acids (substances B), the weight of substance(s) A plus substance(s) B together relative to the weight of the composition being greater than 20%, on the one hand, and the weight of substance(s) A relative to the weight of substance(s) A plus substance(s) B together being greater than 20%, on the other hand. Articles or parts of articles manufactured using this composition.

  由一种或多种聚合物和一种或多种物质组成的组合物，这些物质选自端粒化数平均度小于或等于 8.0的端聚物（物质A）和可选的物质，如邻苯二甲酸二酯或饱和脂肪族二羧酸二酯（物质B），一方面，物质A和物质B加在一起的重量相对于组合物的重量大于20%，另一方面，物质A的重量相对于物质A和物质B加在一起的重量大于20%。使用本组合物制造的物品或物品部件。
• POLYMER COMPOSITIONS COMPRISING TELOMERS AND ARTICLES OR PARTS USING THESE COMPOSITIONS
  申请人：SOLVAY (SOCIETE ANONYME)

  公开号：EP1368422B1

  公开（公告）日：2005-08-24
• US7019068B2
  申请人：——

  公开号：US7019068B2

  公开（公告）日：2006-03-28
• [EN] POLYMER COMPOSITIONS COMPRISING TELOMERS AND ARTICLES OR PARTS USING THESE COMPOSITIONS<br/>[FR] COMPOSITIONS POLYMERES COMPRENANT DES TELOMERES ET DES ARTICLES OU PARTIES D'ARTICLES FABRIQUES A L'AIDE DE CES COMPOSITIONS
  申请人：SOLVAY

  公开号：WO2002057351A1

  公开（公告）日：2002-07-25

  Composition comprising one or more polymers and one or more substances selected from telomers having a number average degree of telomerization of less than or equal to 8.0 (substances A) and optionally from substances such as diesters of phthalic acid or diesters of saturated aliphatic α,ω-dicarboxylic acids (substances B), the weight of substance(s) A plus substance(s) B together relative to the weight of the composition being greater than 20%, on the one hand, and the weight of substance(s) A relative to the weight of substance(s) A plus substance(s) B together being greater than 20%, on the other hand. Articles or parts of articles manufactured using this composition.
• Enantioselective Synthesis of α-Alkyl-β,γ-unsaturated Esters through Efficient Cu-Catalyzed Allylic Alkylations
  作者：Kerry E. Murphy、Amir H. Hoveyda

  DOI：10.1021/ja0300618

  日期：2003.4.1

  A method for enantioselective Cu-catalyzed allylic substitution between various alkylzincs and alpha,beta-unsaturated carboxylic esters that bear a gamma-phosphate is reported. These transformations afford alpha-alkyl-beta,gamma-unsaturated carbonyls with regioselectivities of 7:1 to >20:1 (S(N)2':S(N)2) and in 87-97% ee. The utility of the method is illustrated by a convergent total synthesis of topoisomerse II inhibitor (R)-elenic acid.