(2S,3R)-Astilbin; NSC 245342

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: (2S,3R)-Astilbin; NSC 245342
• 英文别名: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2,3-dihydrochromen-4-one
• 化学式: C₂₁H₂₂O₁₀
• 分子量: 434.4
• InChiKey: VQUPQWGKORWZII-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  166
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• METHODS AND RELATED COMPOSITIONS USING SPECIFIC FLAVONOIDS AND INDANES TO REDUCE WEIGHT AND INHIBIT LIPASE, ALPHA-AMYLASE AND ALPHA-GLUCOSIDASE ACTIVITY IN MAMMALS
  申请人：Oben Julius Enyong

  公开号：US20090076129A1

  公开（公告）日：2009-03-19

  The present invention relates generally to methods and related compositions using flavonoids and/or indanes extracted from the stems and leaves of C. quadrangularis to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals. By example and not by way of limitation, embodiments of the present disclosure, a composition and related methods for reducing body weight and/or inhibiting any combination of lipase, α-amylase and α-glucosidase is provided. The composition contains an effective amount of one or more flavonoids or indanes selected from 3-O-rhamnopyranosylkaempferol, 3-(4-hydroxybenzylidene)-2-(2,5-dihydroxyphenyl)-1-(4-hydroxyphenyl)indane-4,6-diol, quercitrin, rhamnitrin, rhamnocitrin, quercitrin-3-O″-acetate and parthenocissin A.
• US7659313B2
  申请人：——

  公开号：US7659313B2

  公开（公告）日：2010-02-09
• US8362090B2
  申请人：——

  公开号：US8362090B2

  公开（公告）日：2013-01-29
• US8394860B2
  申请人：——

  公开号：US8394860B2

  公开（公告）日：2013-03-12