decane-4,6-diynoic acid | 91061-07-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: decane-4,6-diynoic acid
• 英文别名: deca-4,6-diynoic acid；Deca-4,6-diinsaeure
• CAS: 91061-07-3
• 化学式: C₁₀H₁₂O₂
• 分子量: 164.204
• InChiKey: XCPOOOWWRLQSDS-UHFFFAOYSA-N

物化性质

• 熔点：
  90-91 °C(Solvent: Ethyl acetate; Hexane)
• 沸点：
  327.246±25.00 °C(Press: 760.00 Torr)(predicted)
• 密度：
  1.060±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  decane-4,6-diynoic acid 在 草酰氯 作用下， 以 二氯甲烷 为溶剂， 生成 decane-4,6-diynoic acid chloride
  参考文献：
  名称：

  Synthesis and Self-Assembling Properties of Diacetylene-Containing Glycolipids

  摘要：

  [GRAPHICS]Diacetylene-containing glycolipids are interesting molecules that have many potential applications. The polydiacetylenes formed by the cross-linking of the diacetylene lipids are new stimuli-responsive materials. In particular, diacetylene lipids that can form gels in aqueous solution are of great interest in designing functional biocompatible materials. We have synthesized a series of diacetylene-containing sugar lipids with different chain lengths, substituents, and positions of diyne and studied their self-assembling properties in several solvents including hexane, ethanol, and ethanol/water mixture. Among the 24 diacetylene-containing glycolipids synthesized, many of them exhibited excellent gelation properties in ethanol or ethanol/water mixture. Typically very long chain diacetylene lipids formed gels in ethanol and hexane. Shorter chain diacetylene lipids and compounds with one free hydroxyl group can form gels in aqueous solution. The position of the diyne and chain length affect the self-assembling properties significantly. The systematic study of the gelation properties for diacetylene lipids with different lipid chains can help us to understand the structure requirement for the desired physical properties. Optical microscopy studies showed that the molecules form interesting architectures such as tubules, rods, sheets, and belts. The resulting organogels can also be cross-linked and give different colored polymerized gels depending on their structures.

  DOI：

  10.1021/jo052317t
• 作为产物：
  描述：

  戊-4-炔酸甲酯 在 氢氧化钾 、 ammonium hydroxide 、 氯化铵 、 copper(l) chloride 作用下， 以 甲醇 为溶剂， 反应 5.0h， 生成 decane-4,6-diynoic acid
  参考文献：
  名称：

  百日草及其合成衍生物的聚乙炔的抗菌活性。

  摘要：

  对常见雏菊Bellis perennis L.的气生器官中精油的化学研究表明，聚乙炔是最主要的化合物之一。主要成分：十全-4,6-二壬酸甲酯和十全-4,6-二壬酸甲酯及其结构类似物十全-4,6-二炔，二甲基辛三-3,5-二炔-1,8-二酸酯和合成了deca-4,6-diyne-1,10-diic acid，并评估了其抗菌活性。只有deca-4,6-diynoic acid和deca-4,6-diyne-1,10-diic acid显示出抗菌活性，它们分别是对革兰氏阳性菌和革兰氏阴性菌有效的两种化合物。讨论了所测试的聚乙炔的构效关系。

  DOI：

  10.1055/s-2006-957751

文献信息

• Preparation and Self-Assembly Study of Amphiphilic and Bispolar Diacetylene-Containing Glycolipids
  作者：Guijun Wang、Navneet Goyal、Hari P. R. Mangunuru、Hao Yang、Sherwin Cheuk、Puram V. Narasimha Reddy

  DOI：10.1021/jo501568u

  日期：2015.1.16

  be useful in sensing local environmental changes, we have synthesized a series of novel diacetylene-containing amide and urea derivatives using d-glucosamine as the starting material. Both amphiphilic and dipolar glycolipids were synthesized, and these compounds are effective gelators for several organic solvents and aqueous solutions. The resulting gels can be cross-linked under 6 W UV light to produce

  含二乙炔的糖脂是一类独特的化合物，能够自组装并形成有序的超分子结构。可以用作低分子量胶凝剂的可聚合二乙炔糖脂是特别令人感兴趣的分子，可以导致刺激反应灵敏的智能材料。为了发现具有内置功能的有效有机胶凝剂，该胶凝剂可用于感测局部环境变化，我们使用d合成了一系列新颖的含二乙炔的酰胺和脲衍生物-氨基葡萄糖为起始原料。合成了两亲和偶极糖脂，这些化合物是几种有机溶剂和水溶液的有效胶凝剂。所得的凝胶可以在6 W紫外线下交联，产生蓝色或紫色的聚二乙炔凝胶。由脲衍生物获得的交联凝胶通常是深蓝色，并且在加热时表现出蓝色至红色的转变。与脲衍生物相比，类似的二乙炔酰胺可产生蓝色至深紫色的聚合凝胶，具体取决于胶凝剂的结构。通过光学显微镜和扫描电子显微镜表征凝胶的形态。通常，观察到自组装纤维网络。
• Device and methods for modifying an atmosphere
  申请人：——

  公开号：US20040047760A1

  公开（公告）日：2004-03-11

  The present invention provides a device for modifying an atmosphere in proximity to the device, the device comprising a sachet comprising a semipermeable material, and a composition including a mixture of acetylsalicylic acid and sodium bicarbonate contained within a cavity of the sachet. The invention further provides methods for modifying an atmosphere comprising placing a mixture of a carboxylic acid and a base in the atmosphere, wherein the atmosphere has a sufficient level of water vapor such that, upon contact of the water vapor with the mixture, carbon dioxide is produced.

  本发明提供了一种用于改变靠近该装置的大气环境的装置，该装置包括一个由半透材料组成的小袋，以及一个包含在小袋空腔内的乙酰水杨酸和碳酸氢钠混合物的组合物。本发明进一步提供了改变大气环境的方法，包括将羧酸和碱的混合物置于大气中，其中大气中的水蒸气含量足够高，当水蒸气与混合物接触时，会产生二氧化碳。
• CO2 generating absorbent pads
  申请人：CO2 Technologies, Inc.

  公开号：US20040247750A1

  公开（公告）日：2004-12-09

  A method and means for enhancing the inner environment of a package containing perishable merchandise include taking a closable package containing perishable merchandise and placing in the package a multi-layered sheet including a plurality of layers comprised of moisture absorbing materials to absorb any residual moisture emanating from the perishable merchandise. The multi-layered sheet includes a quantity of CO 2 generating material incorporated therein. The CO 2 generating material is exposable to humidity and any residual moisture within the package and any moisture absorbing material to allow the CO 2 generating material to emit an atmosphere of CO 2 within the package from exposure to moisture within the air in the package, and to absorb any residual moisture in the package.

  一种用于改善装有易腐商品的包装内部环境的方法和装置，包括取一个装有易腐商品的可封闭包装，并在包装内放置一个多层薄片，该多层薄片包括由吸湿材料组成的多层，以吸收易腐商品散发出的任何残余湿气。多层板包括一定量的 CO 2 生成材料。二氧化碳 2 生成材料可暴露于湿度、包装内的任何残留湿气以及任何吸湿材料中，使 CO 2 生成材料释放出二氧化碳气体。 2 并吸收包装内的任何残留湿气。
• Christensen; Soerensen, Acta Chemica Scandinavica (1947), 1952, vol. 6, p. 893,898
  作者：Christensen、Soerensen

  DOI：——

  日期：——
• Prevost,S. et al., Bulletin de la Societe Chimique de France, 1961, p. 2171 - 2175
  作者：Prevost,S. et al.

  DOI：——

  日期：——