2-(3,4-dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol | 121842-80-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(3,4-dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
• CAS: 121842-80-6；71328-22-8；35356-34-4；15514-06-4
• 化学式: C₃₀H₂₆O₁₂
• 分子量: 578.5
• InChiKey: XFZJEEAOWLFHDH-UHFFFAOYSA-N

物化性质

• 沸点：
  955.3±65.0 °C(Predicted)
• 密度：
  1.705±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  42
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  221
• 氢给体数：
  10
• 氢受体数：
  12

文献信息

• Medical devices and methods for local delivery of elastin-stabilizing compounds
  申请人：Biggs Paul David

  公开号：US20070282422A1

  公开（公告）日：2007-12-06

  This invention relates to medical devices and an elastin-stabilizing compound, such as a phenolic tannin, the medical device being adapted to release the elastin-stabilizing compound within a body of a patient. This invention also relates to medical devices and methods of treatment of disease, such as aneurysms and aortic dissection. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters.
• Assays for identification of topoisomerase inhibitors
  申请人：Stivers T. James

  公开号：US20080020973A1

  公开（公告）日：2008-01-24

  The instant invention provides a continuous spectroscopic assay for DNA topoisomerase activity. The invention further provides topoisomerase inhibitors and pharmaceutical compositions for the treatment of topoisomerase associated diseases and disorders.
• Compositions for Regulation of Hair Growth
  申请人：Oblong John Erich

  公开号：US20080254055A1

  公开（公告）日：2008-10-16

  Personal care composition comprising at least one hair growth regulating compound selected from the group consisting of glyceryl dilaurate, apigenin, tetrahydrocurcumin, oleanolic acid, azelaic acid, sulforaphane, canavanine, pyridoxal 5-phosphate, phytic acid, tannic acid, grape seed extract, NG-nitro-L-arginine-methyl ester, benzamidine, sodium butyrate, betulinic acid, polyornithine, polyarginine, fisetin, jasmonates, methyl-jasmonate, cis-jasmone, caffeic acid phenethyl ester, delphinidin, ethyl abietate, esculetin, sorbic acid methyl ester, canaline, N-formyl-methionine, N-formyl-alanine, taurine, palmitoyl carnitine, undecanol, undecylenic acid, rutin, fusidic acid, phenyl pyruvic acid, L-isoleucine, phenyl glycine, silibinin, silymarin, L-ascorbic acid-6-palmitate, N-undecylenoyl-L-phenylalanine, and salts, derivatives and mixtures of any of the foregoing; and a dermatologically-acceptable carrier.
• METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS
  申请人：Reed John C.

  公开号：US20090118135A1

  公开（公告）日：2009-05-07

  An assay for determining compounds that inhibit activity of a BCl-2 protein, or affect conversion of Bcl-2 from an antiapoptotic to a proapoptotic form are described. In addition, compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified.
• PROCESS FOR OBTAINING A TANNIN EXTRACT ISOLATED FROM GRAPES, TANNIN EXTRACT OBTAINED AND USES THEREOF
  申请人：UNIVERSITAT DE LLEIDA

  公开号：US20200121752A1

  公开（公告）日：2020-04-23

  A process is provided for obtaining a tannin extract isolated from grapes using grape seeds. The process comprises: preparing the grape seeds as the source of tannins; preparing an aqueous solution of a polyphenol-solubilising agent selected from urea, a compound containing the SO 3 group and sodium hydroxide at concentration ranging between 1% and 15% by weight; performing a single extraction in an autoclave reactor; separation and direct concentration in order to produce the isolated extract. The invention also relates to the tannin extract obtained. The new tannin extract isolated from grape seeds comprises a mixture of tannins and non-tannins, the composition whereof provides the extract with improved antioxidant and light fastness properties. The tannin extract isolated from grape seeds further comprises a colouring agent.