申请人：Wempe Fitzpatrick Michael
公开号：US20070254859A1
公开（公告）日：2007-11-01
At least one compound chosen from compounds of Formula I:
a pharmaceutically acceptable salt or ester thereof, a solvate thereof, a chelate thereof, a non-covalent complex thereof, a prodrug thereof, and mixtures of any of the foregoing, wherein: n is a number from 1 to 900, wherein the individual units may be the same or different; W is chosen from alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; each of R
2
, R
3
, R
4
and R
5
is independently chosen from —H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; Z′ is chosen from —O—, —N—, —NO—, —NR
4
—, —S—, —SO— and —SO
2
—, wherein R
4
is defined as above; each of X, X′, Y and Z is independently chosen from —CR
4
R
5
—, —NH—, —NR
4
—, —NO—, —O—, —NOR
4
—, —S—, —SO—, —SO
2
—, wherein R
4
and R
5
are defined as above; R
1
is chosen from a tocopherol, a steroid and a flavonoid; and R
6
is chosen from any R
1
, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl.
