5-acetyl-7-[5-carboxy-3-[(8,9-dihydroxy-2-methyl-4-oxo-5H-pyrano[3,2-c]chromen-3-yl)methyl]-6,7-dihydroxy-4-oxochromen-2-yl]-2,3-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5-acetyl-7-[5-carboxy-3-[(8,9-dihydroxy-2-methyl-4-oxo-5H-pyrano[3,2-c]chromen-3-yl)methyl]-6,7-dihydroxy-4-oxochromen-2-yl]-2,3-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylic acid
• 化学式: C₄₁H₂₆O₁₈
• 分子量: 806.6
• InChiKey: ZVSBWQUWQXWZJH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  59
• 可旋转键数：
  6
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  301
• 氢给体数：
  8
• 氢受体数：
  18

文献信息

• Nerve regeneration promoters containing semaphorin inhibitor as the active ingredient
  申请人：Kimura Toru

  公开号：US20070015820A1

  公开（公告）日：2007-01-18

  To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like. A low-molecular weight compound, which acts at a concentration of 10 μg/ml or below to inhibit the growth cone collapse activity of semaphorin such as semaphorin 3A, semaphorin 6C or the like and/or the nerve outgrowth inhibitory activity of semaphorin in a collagen gel and which does not substantially affect cell proliferation, is obtained from the culture of strain SPF-3059 belonging to the genus Penicillium. The low-molecular weight compound with the semaphorin inhibitory activity thus obtained exhibits the in vivo nerve-regeneration promoting action.
• Therapeutic or preventive agents for ischemic neuropathy
  申请人：Ikeda Kazuhito

  公开号：US20070105948A1

  公开（公告）日：2007-05-10

  Therapeutic or preventive agents for ischemic nerve injury containing as the active ingredient compounds represented by the general formula [2]: wherein R 1 and R 4 are each independently hydrogen, carboxy, or alkoxycarbonyl; and R 2 and R 5 are each independently hydrogen, hydroxy group, or acyloxy group.
• THERAPEUTIC OR PREVENTIVE AGENTS FOR ISCHEMIC NEUROPATHY
  申请人：IKEDA Kazuhito

  公开号：US20110105599A1

  公开（公告）日：2011-05-05

  Therapeutic or preventive agents for ischemic nerve injury containing as the active ingredient compounds represented by the general formula [2]: wherein R 1 and R 4 are each independently hydrogen, carboxy, or alkoxycarbonyl; and R 2 and R 5 are each independently hydrogen, hydroxy group, or acyloxy group.
• US7244761B2
  申请人：——

  公开号：US7244761B2

  公开（公告）日：2007-07-17
• US7317038B2
  申请人：——

  公开号：US7317038B2

  公开（公告）日：2008-01-08