3-(3-methoxy-phenoxy)-propionic acid ethyl ester | 876488-84-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(3-methoxy-phenoxy)-propionic acid ethyl ester
• 英文别名: 3-(3-Methoxy-phenoxy)-propionsaeure-aethylester；Ethyl 3-(3-methoxyphenoxy)propanoate
• CAS: 876488-84-5
• 化学式: C₁₂H₁₆O₄
• 分子量: 224.257
• InChiKey: ONTYVXDDAFGBAF-UHFFFAOYSA-N

物化性质

• 沸点：
  331.6±22.0 °C(Predicted)
• 密度：
  1.083±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-(3-methoxy-phenoxy)-propionic acid ethyl ester 在 sodium hydroxide 、 三氯化铝 、 硝基苯 作用下， 生成 紫外线吸收剂 UV-9
  参考文献：
  名称：

  Simpson et al., Journal of the Chemical Society, 1951, p. 2239,2243

  摘要：

  DOI：
• 作为产物：
  描述：

  3,4-二甲氧基苯甲酰氯 在 三氯化铝 、 硝基苯 作用下， 生成 3-(3-methoxy-phenoxy)-propionic acid ethyl ester
  参考文献：
  名称：

  Simpson et al., Journal of the Chemical Society, 1951, p. 2239,2243

  摘要：

  DOI：

文献信息

• DNA-protein interaction at erythroid important regulatory elements of MEL cells byin vivo footprinting
  作者：Xinjun Ji、Depei Liu、Dongdong Xu、Lei Li、Jing Wang、Zhiquan Liang

  DOI：10.1007/bf02887183

  日期：2000.6

  Using ligation-mediated PCR method to study the status of DNA-protein interaction at hypersensitive site 2 of locus control Region and beta(maj) promoter of MEL cell line before and after induction, MEL cell has been cultured and induced to differentiation by Hemin and DMSO, then the live cells have-been treated with dimethyl sulfate. Ligation mediated PCR has been carried out following the chemical cleavage. The results demonstrate that before and after induction, the status of DNA-protein interaction at both hypersensitive site 2 and beta(maj) promoter change significantly, indicating that distal regulatory elements (locus control region, hypersensitive sites) as well as proximal regulatory elements (promoter, enhancer) of beta-globin gene cluster participate in the regulation of developmental specificity.
• Simpson et al., Journal of the Chemical Society, 1951, p. 2239,2243
  作者：Simpson et al.

  DOI：——

  日期：——