2-[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulfinyl]ethyl methacrylate | 917967-01-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulfinyl]ethyl methacrylate
• 英文别名: 2-(3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctylsulfinyl)ethyl 2-methylprop-2-enoate
• CAS: 917967-01-2
• 化学式: C₁₄H₁₃F₁₃O₃S
• 分子量: 508.301
• InChiKey: XTVYAAPVUWIWAJ-UHFFFAOYSA-N

物化性质

• 沸点：
  377.9±42.0 °C(Predicted)
• 密度：
  1.501±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  31
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  62.6
• 氢给体数：
  0
• 氢受体数：
  17

反应信息

• 作为产物：
  描述：

  1-碘-1H,1H,2H,2H-全氟辛烷 在 sodium hydroxide 、 sodium periodate 、 三乙胺 作用下， 以 甲醇 、 乙醚 、 水 、 叔丁醇 为溶剂， 反应 14.0h， 生成 2-[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulfinyl]ethyl methacrylate
  参考文献：
  名称：

  New perfluoroalkylated amphiphilic methacrylates bearing sulfinyl group as monomers for biomedical applications: water content and oxygen permeability of their copolymers with DEGMA

  摘要：

  Perfluoroalkylated methacrylates 7a-c bearing sulfinyl group within a straight-chain ester group, i.e. CH2=C(CH3)CO2CH2CH2S(O)CH2CH2CF2(CF2CF2)(n)CF3 (n = 1-3) were prepared by two alternative synthetic sequences from 2-[(polyfluoroalkyl)sulfanyl]ethanols HOCH2CH2SCH2CH2CF2(CF2CF2)(n)CF3 (n = 1-3) in overall yields of 88-91%. Copolymers of 7a-c with diethylene glycol methacrylate (DEGMA) prepared in bulk under radical conditions display high transparency, increased water content and good oxygen permeability properties, which are advantageous for their application in ophthalmology and as prosthetic materials. (c) 2006 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2006.06.003

文献信息

• New perfluoroalkylated amphiphilic methacrylates bearing sulfinyl group as monomers for biomedical applications: water content and oxygen permeability of their copolymers with DEGMA
  作者：Vladimír Církva、Jan Duchek、Robert Kaplánek、Oldřich Paleta、Jiří Michálek、Martin Přádný、Dana Chmelíková、Jana Wichterlová

  DOI：10.1016/j.ejmech.2006.06.003

  日期：2006.11

  Perfluoroalkylated methacrylates 7a-c bearing sulfinyl group within a straight-chain ester group, i.e. CH2=C(CH3)CO2CH2CH2S(O)CH2CH2CF2(CF2CF2)(n)CF3 (n = 1-3) were prepared by two alternative synthetic sequences from 2-[(polyfluoroalkyl)sulfanyl]ethanols HOCH2CH2SCH2CH2CF2(CF2CF2)(n)CF3 (n = 1-3) in overall yields of 88-91%. Copolymers of 7a-c with diethylene glycol methacrylate (DEGMA) prepared in bulk under radical conditions display high transparency, increased water content and good oxygen permeability properties, which are advantageous for their application in ophthalmology and as prosthetic materials. (c) 2006 Elsevier Masson SAS. All rights reserved.