2,4-Dichlorobenzhydroximic acid chloride | 29203-60-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-Dichlorobenzhydroximic acid chloride
• 英文别名: (1E)-2,4-dichloro-N-hydroxybenzenecarboximidoyl chloride
• CAS: 29203-60-9
• 化学式: C₇H₄Cl₃NO
• 分子量: 224.474
• InChiKey: GXBVZCSCOBTMHS-YRNVUSSQSA-N

物化性质

• 熔点：
  93 °C

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  C
• 危险类别码：
  R34
• 海关编码：
  2925290090

SDS

Name:	2 4-Dichloro-n-hydroxybenzenecarboximidoyl chloride 97% Material Safety Data Sheet
Synonym:	alpha-2,4-Trichlorobenzaldoxim
CAS:	29203-60-9

Section 1 - Chemical Product MSDS Name:2 4-Dichloro-n-hydroxybenzenecarboximidoyl chloride 97% Material Safety Data Sheet
Synonym:alpha-2,4-Trichlorobenzaldoxim

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
29203-60-9	2,4-Dichloro-N-hydroxybenzenecarboximi	97%	unlisted

Hazard Symbols: C
Risk Phrases: 34

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

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Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area. Store under an inert atmosphere.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 29203-60-9: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 94 - 96 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C7H4Cl3NO
Molecular Weight: 224

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, bases, amines.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 29203-60-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2,4-Dichloro-N-hydroxybenzenecarboximidoyl chloride - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE SOLID, N.O.S.*
Hazard Class: 8
UN Number: 1759
Packing Group: III
IMO
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing group: III

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 29203-60-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 29203-60-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 29203-60-9 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2,4-Dichlorobenzhydroximic acid chloride 在 三甲基氯硅烷 、 scandium tris(trifluoromethanesulfonate) 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 生成 3-(2,4-Dichlorophenyl)-6-methyl-5,6-dihydro-2H-1,2,4-oxadiazine
  参考文献：
  名称：

  Scandium(III) triflate–TMSCl promoted cyclization of aziridin-1-yl oximes to 5,6-dihydro-4H-[1,2,4]oxadiazines

  摘要：

  A convenient and facile one-pot synthesis of 5,6-dihydro-4H-[1,2,4]oxadiazine is described. Treatment of aziridin-1-yl-oximes with Scandium(III) triffate readily afforded 5,6-dihydro-4H-[1,2,4]oxadiazine in the presence of chlorotrimethylsilane. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.10.096

文献信息

• POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF
  申请人：SAGAMI CHEMICAL RESEARCH INSTITUTE

  公开号：US20160024110A1

  公开（公告）日：2016-01-28

  Provided are a polycyclic pyrazolinone derivative indicated by general formula (1) (in the formula, R 1 , X 1 , X 2 , X 3 , and Y indicate the definitions provided in the Specification) and a herbicide comprising same as effective component thereof.

  提供了一个由通式（1）表示的多环吡唑酮衍生物（在该式中，R1、X1、X2、X3和Y表示规范中提供的定义），以及包含其作为有效成分的除草剂。
• Regio- and stereoselective 1,3-dipolar cycloaddition of arylnitrile oxides to 5-acetoxy-2(5H)-furanone
  作者：Peter Oravec、Ľubor Fišera、Roman Gažo

  DOI：10.1007/bf00809361

  日期：1991.3

  Arylnitrile oxides undergo regio- and stereo-specific 1,3-dipolar cycloaddition reactions with 5-acetoxy-2(5H)-furanone. In each case a single product 3a-3g results from an anti approach to the 5-acetoxy substituent, the oxygen of the 1,3-dipole being attached to C-4 of furan. Under similar conditions 5-benzoyloxy-2(5H)-furanone yields 3h-3i. The structures of the adducts were determined by H-1 and C-13-NMR spectroscopy.
• Facile three-component domino reactions for the synthesis of 2-arylimidazo[1,2-a]pyridines and 2-arylimidazo[2,1-a]isoquinolines
  作者：Pitchaimani Prasanna、Sundaravel Vivek Kumar、Pethaiah Gunasekaran、Subbu Perumal

  DOI：10.1016/j.tetlet.2013.04.126

  日期：2013.7

  The three-component domino reactions of pyridine/isoquinoline, phenacyl bromide, and substituted (E)-N-hydroxyarylimidoyl chloride in the presence of triethylamine afforded a series of 2-arylimidazo[1,2-a]pyridines and 2-arylimidazo[2,1-a]isoquinolines. This one pot three-component transformation presumably proceeds via ylide generation/annulation/fragmentation/clehydration domino sequence of reactions. (C) 2013 Elsevier Ltd. All rights reserved.
• US9580444B2
  申请人：——

  公开号：US9580444B2

  公开（公告）日：2017-02-28
• Scandium(III) triflate–TMSCl promoted cyclization of aziridin-1-yl oximes to 5,6-dihydro-4H-[1,2,4]oxadiazines
  作者：Sung Yun Cho、Seung Kyu Kang、Jin Hee Ahn、Jae Du Ha、Joong-Kwon Choi

  DOI：10.1016/j.tetlet.2006.10.096

  日期：2006.12

  A convenient and facile one-pot synthesis of 5,6-dihydro-4H-[1,2,4]oxadiazine is described. Treatment of aziridin-1-yl-oximes with Scandium(III) triffate readily afforded 5,6-dihydro-4H-[1,2,4]oxadiazine in the presence of chlorotrimethylsilane. (c) 2006 Elsevier Ltd. All rights reserved.