5-[5-(2,3-Dichloro-phenyl)-tetrazol-1-ylmethyl]-2-nitro-pyridine | 1186082-03-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-[5-(2,3-Dichloro-phenyl)-tetrazol-1-ylmethyl]-2-nitro-pyridine
• 英文别名: 5-[[5-(2,3-Dichlorophenyl)tetrazol-1-yl]methyl]-2-nitropyridine
• CAS: 1186082-03-0
• 化学式: C₁₃H₈Cl₂N₆O₂
• 分子量: 351.152
• InChiKey: IKWFLOVRIQLIIZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  102
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• IMAGING THE CENTRAL NERVOUS SYSTEM
  申请人：Jones Paul Alexander

  公开号：US20110027178A1

  公开（公告）日：2011-02-03

  The present invention provides novel compounds which may be used as in vivo imaging agents. The compounds of the invention are useful in a method to image the expression of P2X 7 receptors in a subject, as a means to facilitate the diagnosis of a range of disease states.

  本发明提供了新型化合物，可用作体内成像剂。本发明的化合物可用于成像受体P2X7在受试者中的表达，作为一种促进多种疾病状态诊断的手段。
• [EN] IMAGING THE CENTRAL NERVOUS SYSTEM<br/>[FR] IMAGERIE DU SYSTÈME NERVEUX CENTRAL
  申请人：GE HEALTHCARE LTD

  公开号：WO2009106564A2

  公开（公告）日：2009-09-03

  The present invention provides novel compounds which may be used as in vivo imaging agents. The compounds of the invention are useful in a method to image the expression of P2X7 receptors in a subject, as a means to facilitate the diagnosis of a range of disease states.