2-stearoyloxyethyl dihydrogen phosphate | 99887-44-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-stearoyloxyethyl dihydrogen phosphate
• 英文别名: (2-stearoyloxyethyl)phosphoric acid；2-(phosphonooxy)ethyl stearate；1-phosphonooxy-2-stearoyloxy-ethane；1-Phosphonooxy-2-stearoyloxy-aethan；2-Phosphonooxyethyl octadecanoate
• CAS: 99887-44-2
• 化学式: C₂₀H₄₁O₆P
• 分子量: 408.516
• InChiKey: NQKYLBYXYCYLAJ-UHFFFAOYSA-N

物化性质

• 熔点：
  89-90 °C
• 沸点：
  526.1±52.0 °C(Predicted)
• 密度：
  1.053±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  27
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  phosphoric acid diphenyl ester-(2-stearoyloxy-ethyl ester) 在 1,4-二氧六环 、 platinum on activated charcoal 作用下， 生成 2-stearoyloxyethyl dihydrogen phosphate
  参考文献：
  名称：

  van der Neut et al., Recueil des Travaux Chimiques des Pays-Bas, 1953, vol. 72, p. 365,368,375

  摘要：

  DOI：

文献信息

• Amplified luminescent homogeneous immunoassay
  申请人：——

  公开号：US20040175696A1

  公开（公告）日：2004-09-09

  Methods are disclosed for determining minute quantities of an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a substrate having an oxidant cleavable linker and a photosenstizer to come into close proximity. The photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay such as LOCI. The amount of product detected is related to the amount of analyte in the medium. Compositions, kits, and compounds are also disclosed.

  本发明公开了一种用于确定疑似含有分析物的介质中微量分析物的方法。其中一种方法包括在条件下处理疑似含有分析物的介质，使得如果分析物存在，则会使得具有氧化剂可分解连接剂和光敏剂的底物进入接近状态。光敏剂产生单线态氧，氧化性地裂解连接剂形成可在夹心检测测定（如LOCI）中检测到的产物。检测到的产物量与介质中分析物的量有关。本发明还公开了组合物、试剂盒和化合物。
• Assay methods utilizing induced luminescence
  申请人：BEHRINGWERKE Aktiengesellschaft

  公开号：EP0515194A2

  公开（公告）日：1992-11-25

  Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte; if present, causes a photosensitizer and a chemiluminescent compound to come into close proximity. The photosensitizer generates singlet oxygen and activates the chemiluminescent compound when it is in close proximity. The activated chemiluminescent compound subsequently produces light. The amount of light produced is related to the amount of analyte in the medium. Preferably, at least one of the photosensitizer and chemiluminescent compound is associated with a surface which is usually a suspendible particle, and a specific binding pair member is bound thereto. Another method comprises providing (1) a medium suspected of containing the analyte, (2) a label reagent comprising a first specific binding pair (sbp) member associated with a photochemically activatable chemiluminescent compound wherein the first sbp member is capable of binding to the analyte or to a second sbp member to form a complex related to the presence of the analyte. This method further comprises photochemically activating the chemiluminescent compound. The amount of luminescence generated by the chemiluminescent compound is detected. The amount thereof is related to the amount of analyte in the medium. Compositions and kits are also disclosed.

  本发明公开了测定疑似含有分析物的介质中分析物的方法。 其中一种方法包括处理疑似含有分析物的介质，处理条件是分析物（如果存在）会导致光敏剂和化学发光化合物接近。光敏剂产生单线态氧，并在靠近时激活化学发光化合物。被激活的化学发光化合物随后产生光。产生的光量与介质中分析物的含量有关。光敏剂和化学发光化合物中的至少一种最好与表面（通常是可悬浮颗粒）相关联，并与特定的结合对成员结合。 另一种方法包括：(1) 提供疑似含有分析物的介质；(2) 标签试剂，包括与光化学可激活的化学发光化合物相关的第一特异性结合对（sbp）成员，其中第一 sbp 成员能够与分析物或第二 sbp 成员结合，形成与分析物存在相关的复合物。该方法还包括光化学激活化学发光化合物。检测化学发光化合物产生的发光量。其数量与介质中分析物的数量相关。 此外，还公开了组合物和试剂盒。
• A homogeneous assay for determining analyte
  申请人：Dade Behring Marburg GmbH

  公开号：EP0984281A2

  公开（公告）日：2000-03-08

  Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises providing in combination (1) a medium suspected of containing an analyte; (2) a label reagent comprising a suspendible particle and a first specific binding pair (sbp) member associated with a photochemically activatable chemiluminescent compound (PACC), wherein said first sbp member is capable of binding to said analyte or to a second sbp member, wherein said second sbp member is capable of binding to said analyte; and (3) an intrinsically metastable species capable of diffusing in said medium and of reacting preferentially with said PACC when said PACC is brought into close proximity to said species by virtue of the presence or absence of said analyte; and determining whether said intrinsically metastable species has reacted with said PACC, the reaction thereof being related to the amount of analyte in said medium.

  本发明公开了用于确定疑似含有被分析物的介质中的被分析物的方法。 一种方法包括提供以下组合：(1) 被怀疑含有被分析物的介质；(2) 标签试剂，包括可悬浮颗粒和与光化学可激活化学发光化合物（PACC）相关的第一特异性结合对（sbp）成员，其中所述第一sbp成员能够与所述被分析物或第二sbp成员结合，其中所述第二sbp成员能够与所述被分析物结合；(3) 本征可转移物种，能够在所述介质中扩散，并且当所述 PACC 因所述分析物的存在或不存在而靠近所述物种时，能够优先与所述 PACC 反应；以及确定所述本征可转移物种是否与所述 PACC 反应，其反应与所述介质中分析物的量有关。
• Gastrointestinal tract detection methods, devices and systems
  申请人：Progenity Inc.

  公开号：US10610104B2

  公开（公告）日：2020-04-07

  The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

  本公开涉及胃肠道（GI）检测方法、装置和系统。
• Rasadkina, E. N.; Predvoditelev, D. A.; Kozlova, G. G., Journal of Organic Chemistry USSR (English Translation), 1991, vol. 27, # 3.1, p. 431 - 436
  作者：Rasadkina, E. N.、Predvoditelev, D. A.、Kozlova, G. G.、Nifant'ev, E. E.

  DOI：——

  日期：——