2-heptyl-2-methyl-nonanoic acid | 123298-00-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-heptyl-2-methyl-nonanoic acid
• 英文别名: 2-Heptyl-2-methyl-nonansaeure；2-heptyl-2-methylnonanoic acid
• CAS: 123298-00-0
• 化学式: C₁₇H₃₄O₂
• 分子量: 270.456
• InChiKey: PSQHFWDUJHPBQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-heptyl-2-methyl-nonanoic acid 在 氯化亚砜 作用下， 生成 2-heptyl-2-methyl-nonanoic acid amide
  参考文献：
  名称：

  Polgar; Robinson, Journal of the Chemical Society, 1943, p. 618

  摘要：

  DOI：
• 作为产物：
  描述：

  2-heptyl-2-methyl-nonanenitrile 在 盐酸 、 亚硝酸丁酯 、 硫酸 、 苯 作用下， 生成 2-heptyl-2-methyl-nonanoic acid
  参考文献：
  名称：

  Sperber; Papa; Schwenk, Journal of the American Chemical Society, 1948, vol. 70, p. 3092

  摘要：

  DOI：

文献信息

• Production of neo acids from biomass-derived monomers
  作者：Erha Andini、Jake Bragger、Sunitha Sadula、Dionisios G. Vlachos

  DOI：10.1039/d3gc00735a

  日期：——

  currently produced from fossil fuels. In this work, we produce renewable neo acids from lignocellulosic biomass-derived furan and keto acids via C–C coupling through hydroxyalkylation/alkylation (HAA), followed by ring-opening of furans through hydrodeoxygenation (HDO). We show effective C–C coupling over acid catalysts. Catalyst screening and multi-parameter optimization using machine learning optimize

  新酸是目前由化石燃料生产的高度支化的羧酸。在这项工作中，我们通过羟基烷基化/烷基化 (HAA) 的 C-C 偶联，然后通过加氢脱氧 (HDO) 使呋喃开环，从木质纤维素生物质衍生的呋喃和酮酸中生产可再生新酸。我们展示了在酸催化剂上有效的 C-C 偶联。使用机器学习进行催化剂筛选和多参数优化可优化产量并阐明变量与结果之间的相关性。我们展示了在不影响羧酸的情况下使用涉及负载在碳和金属三氟甲磺酸盐上的 Pd 的助催化剂来制造新酸的选择性呋喃开环。
• DISPERSION LIQUID AND HYDROGEL FORMATION METHOD
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2865442A1

  公开（公告）日：2015-04-29

  There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator, such as a lipid dipeptide and a lipid tripeptide, and a solvent capable of dissolving the lipid peptide type compound at a lower temperature more easily. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and under a milder condition (low temperature) and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel. A dispersion comprising a lipid peptide type compound in which a peptide portion having an amino acid repeating bonding structure is bonded to a lipid portion consisting of a C9-23 aliphatic group; and at least one alcohol selected from the group consisting of 1,2-alkanediol, 1,3-alkanediol, and ethylene glycol monoalkyl ether or a mixed solution of the at least one alcohol and water; and a method for producing a hydrogel by use of the dispersion.

  本发明提供了一种含有可用作低分子量凝胶剂的脂质肽类化合物（如脂质二肽和脂质三肽）的分散液，以及一种能够在较低温度下更容易溶解脂质肽类化合物的溶剂。本发明还提供了一种分散液，可通过更简单的方法在更温和的条件下（低温）形成水凝胶，并从中获得具有高热稳定性的凝胶，同时还提供了形成凝胶的方法。一种包含脂肽型化合物的分散液，其中具有氨基酸重复键合结构的肽部分与由 C9-23 脂肪族基团组成的脂质部分键合；以及至少一种选自 1,2-烷二醇、1,3-烷二醇和乙二醇单烷基醚或至少一种醇和水的混合溶液组成的组的醇，以及一种通过使用该分散液生产水凝胶的方法。
• DISPERSION AND METHOD FOR FORMING HYDROGEL
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：EP3296013A1

  公开（公告）日：2018-03-21

  There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator, such as a lipid dipeptide and a lipid tripeptide, and a solvent capable of dissolving the lipid peptide type compound at a lower temperature more easily. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and under a milder condition (low temperature) and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel. A dispersion comprising a lipid peptide type compound in which a peptide portion having an amino acid repeating bonding structure is bonded to a lipid portion consisting of a C9-23 aliphatic group; and at least one alcohol selected from the group consisting of 1,2-alkanediol, 1,3-alkanediol, and ethylene glycol monoalkyl ether or a mixed solution of the at least one alcohol and water; and a method for producing a hydrogel by use of the dispersion.

  本发明提供了一种含有可用作低分子量凝胶剂的脂质肽类化合物（如脂质二肽和脂质三肽）的分散液，以及一种能够在较低温度下更容易溶解脂质肽类化合物的溶剂。本发明还提供了一种分散液，可通过更简单的方法在更温和的条件下（低温）形成水凝胶，并从中获得具有高热稳定性的凝胶，同时还提供了形成凝胶的方法。一种包含脂肽型化合物的分散液，其中具有氨基酸重复键合结构的肽部分与由 C9-23 脂肪族基团组成的脂质部分键合；以及至少一种选自 1,2-烷二醇、1,3-烷二醇和乙二醇单烷基醚或至少一种醇和水的混合溶液组成的组的醇，以及一种通过使用该分散液生产水凝胶的方法。
• COSMETIC COMPOSITION
  申请人：Rohto Pharmaceutical Co., Ltd.

  公开号：EP3616683A1

  公开（公告）日：2020-03-04

  Provided is a cosmetic composition that maintains high stability and restrains from becoming cloud. This cosmetic composition is prepared by including (A) polyoxyethylene polyoxypropylene glycol, and (B) an amino acid based surfactant having, in a single molecule thereof, two or more hydrophobic groups and two or more hydrophilic groups. Furthermore, provided is a method of giving a cloudiness-restraining effect to a cosmetic composition, including causing the component (A) and the component (B) to coexist with each other in the cosmetic composition.

  本发明提供了一种化妆品组合物，它能保持高稳定性并防止变浊。 这种化妆品组合物的制备方法是：(A) 聚氧乙烯聚氧丙烯二醇；(B) 氨基酸基表面活性剂，在其单个分子中具有两个或两个以上的疏水基团和两个或两个以上的亲水基团。此外，还提供了一种使化妆品组合物具有抑浊效果的方法，包括使组分（A）和组分（B）在化妆品组合物中共存。
• Dispersion and method for forming hydrogel
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US10421055B2

  公开（公告）日：2019-09-24

  There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator and a solvent capable of dissolving the lipid peptide type compound at a lower temperature. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel. A dispersion including a lipid peptide type compound in which a peptide portion having an amino acid repeating bonding structure is bonded to a lipid portion consisting of a C9-23 aliphatic group; and at least one alcohol selected from the group consisting of 1,2-alkanediol, 1,3-alkanediol, and ethylene glycol monoalkyl ether or a mixed solution of the at least one alcohol and water; and a method for producing a hydrogel by use of the dispersion.

  本发明提供了一种含有可用作低分子量凝胶剂的脂肽类化合物的分散体，以及一种能够在较低温度下溶解脂肽类化合物的溶剂。本发明还提供了一种分散液，可通过更简单的方法从中形成水凝胶，并从中获得具有高热稳定性的凝胶，同时还提供了形成凝胶的方法。一种分散液，包括脂肽型化合物，其中具有氨基酸重复键合结构的肽部分与由 C9-23 脂肪族基团组成的脂质部分键合；以及至少一种选自 1,2-烷二醇、1,3-烷二醇和乙二醇单烷基醚或至少一种醇和水的混合溶液组成的组中的醇；以及一种通过使用该分散液生产水凝胶的方法。