dimethacrylate methyldiethanolamine | 18452-81-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: dimethacrylate methyldiethanolamine
• 英文别名: N-Methyl-diaethanolamin-dimethacrylat；N-Methyldiethanolamin-dimethacrylat；N,N-bis(methacryloxyethyl)methylamine；N-methyl-N-di(ethanolaminemethacrylate)；2-[Methyl-[2-(2-methylprop-2-enoyloxy)ethyl]amino]ethyl 2-methylprop-2-enoate
• CAS: 18452-81-8
• 化学式: C₁₃H₂₁NO₄
• 分子量: 255.314
• InChiKey: JUPWMYAEFOZKSJ-UHFFFAOYSA-N

物化性质

• 沸点：
  338.8±27.0 °C(Predicted)
• 密度：
  1.033±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1,4-丁磺酸内酯 、 dimethacrylate methyldiethanolamine 以 丙酮 为溶剂， 以64%的产率得到N,N-bis(methacryloxyethyl)-N-methyl-N-(4-sulfobutyl)ammonium betaine
  参考文献：
  名称：

  Zwitterionic hydrogels crosslinked with novel zwitterionic crosslinkers: Synthesis and characterization

  摘要：

  Two novel zwitterionic sulfobetaine dimethacrylate crosslinkersN,N-bis(methacryloxyethyl)-N-methyl-N-(3-sulfopropyl)ammonium (CL1) and N,N-bis(methacryloxyethyl)-N-methyl-N-(4-sulfobutyl)ammonium (CL2) betaines were synthesized and used for preparation of zwitterionic hydrogels formed from N-(methacryloxyethyl)-N,N-dimethyl-N-(3-sulfopropyl)ammonium betaine (SBDMA) via redox-initiated free-radical polymerization. The commercially available crosslinkers N,N'-methylene bisacrylamide (BIS) and ethylene glycol dimethacrylate (EDMA) were also used. Equilibrium water content, sorption degree, diffusion coefficient of water, state of water, degree of crosslinking and mechanical properties were determined for hydrogels crosslinked using different crosslinking conditions. A minor difference in the spacer length between the charged moieties in CL1 and CL2 crosslinkers, respectively, was shown to influence the hydrogel properties. The CL1 and CL2 crosslinkers with chemical structure similar to SBDMA resulted in hydrogels with higher stiffness, mechanical strength and crosslink density compared to hydrogels crosslinked by BIS and EDMA. This difference was assigned to suppression of the compositional drift during the hydrogel formation when crosslinkers with chemical structure similar to monomer were used. PolySBDMA hydrogels exhibited a low adhesion of RAT-2 fibroblasts-like cells. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2011.04.056
• 作为产物：
  描述：

  甲基丙烯酸 、 N-甲基二乙醇胺 在 甲烷磺酸 、 对苯二酚 作用下， 以 甲苯 为溶剂， 以73%的产率得到dimethacrylate methyldiethanolamine
  参考文献：
  名称：

  [EN] CROSSLINKED ZWITTERIONIC HYDROGELS
  [FR] HYDROGELS ZWITTERIONIQUES RÉTICULÉS

  摘要：

  公开号：

  WO2011057219A3

文献信息

• 一种合成丙烯酸二乙醇胺酯类化合物的方法
  申请人：中国海洋石油总公司

  公开号：CN105503625A

  公开（公告）日：2016-04-20

  本发明涉及一种合成丙烯酸二乙醇胺酯类化合物的方法。本发明方法包括以下步骤：向反应器中加入有机溶剂、催化剂、阻聚剂和丙烯酸甲酯或者甲基丙烯酸甲酯，向反应体系中滴加二乙醇胺类化合物，在0～90℃下反应0.5～12h，生成丙烯酸二乙醇胺酯类化合物；其中，所述催化剂与丙烯酸甲酯或甲基丙烯酸甲酯的摩尔比为0.01～15％；丙烯酸甲酯或者甲基丙烯酸甲酯与二乙醇胺类化合物的摩尔比为2.0：1～10.0：1；所述的催化剂为负载型溴化锌；本发明方法能够在比较温和实验条件下，高效率、环保制备丙烯酸二乙醇胺酯类产品。
• DENTAL POLYMERIZABLE MONOMER COMPOSITIONS
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20170181932A1

  公开（公告）日：2017-06-29

  Provided are dental polymerizable monomer compositions that can give cured products having high toughness and high rigidity, and dental compositions containing such dental polymerizable monomer compositions and cured products thereof having high mechanical properties. The dental polymerizable monomer composition includes a urethane acrylate compound (A) and a polymerizable compound (B) having at least one polymerizable group selected from methacryloyl groups and acryloyl groups, the urethane acrylate compound (A) being obtained by reacting a specific hydroxyacrylate (a1) with a diisocyanate (a2) having two isocyanate groups bonded to a divalent C 6-9 aromatic hydrocarbon group or a divalent C 6-9 bridged cyclic hydrocarbon group via a methylene group optionally substituted with a hydrocarbon group in place of a hydrogen atom, the proportion of the number of acryloyl groups present in the urethane acrylate compound (A) being 10% to less than 90% relative to the total number of (meth)acryloyl groups in the monomer composition.

  提供了一种牙科可聚合单体组合物，可使固化产物具有高韧性和高刚度，并且含有这种牙科可聚合单体组合物和具有高机械性能的固化产物的牙科组合物。该牙科可聚合单体组合物包括一种脲基丙烯酸酯化合物（A）和一种具有至少一种可聚合基团，所述可聚合基团选自甲基丙烯酰基团和丙烯酰基团的可聚合化合物（B），脲基丙烯酸酯化合物（A）是通过将特定的羟基丙烯酸酯（a1）与具有两个异氰酸基团与一个二价C6-9芳香烃基或一个二价C6-9桥环烃基通过一个亚甲基团或者可选地替代氢原子的烃基的甲烷基团相结合的二异氰酸酯（a2）反应而得到的，相对于单体组合物中（甲）丙烯酰基团的总数，脲基丙烯酸酯化合物（A）中存在的丙烯酰基团的比例为10%至90%。
• NOVEL COMPOUND, COMPOSITION COMPRISING THE COMPOUND AND CURED PRODUCT
  申请人：NARUSE Hiroshi

  公开号：US20120296061A1

  公开（公告）日：2012-11-22

  The present invention provides a novel compound and a composition including the compound that exhibit small polymerization shrinkage particularly during curing and are producible at low cost on the industrial scale. The compound of the present invention is represented by Formula ( 1 ):

  本发明提供了一种新型化合物和包括该化合物的组合物，特别是在固化过程中表现出小的聚合收缩，并且可以在工业规模下以低成本生产。本发明的化合物由式（1）表示：
• DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT
  申请人：NARUSE Hiroshi

  公开号：US20120296003A1

  公开（公告）日：2012-11-22

  The present invention provides a dental material, a dental material composition and a dental restorative material that exhibit small polymerization shrinkage particularly during curing and are producible at low cost on the industrial scale. The dental material of the present invention includes a specific urethane (meth)acrylic compound represented by Formula (1) described below.

  本发明提供了一种牙科材料、牙科材料组合物和一种在固化过程中特别具有小聚合收缩并且可以在工业规模下低成本生产的牙科修复材料。本发明的牙科材料包括下面描述的由式（1）表示的特定脲（甲）丙烯酸酯化合物。
• Cation-Condensed Microgel-Core Star Polymers as Polycationic Nanocapsules for Molecular Capture and Release in Water
  作者：Kaoru Fukae、Takaya Terashima、Mitsuo Sawamoto

  DOI：10.1021/ma300266k

  日期：2012.4.24

  ruthenium-catalyzed living radical polymerization. Analyzed by UV–vis spectroscopy, the star polymer efficiently encapsulated various hydrophilic dyes carrying sulfonate anions (methyl orange: MO; orange G: OG; methyl blue: MB) in water (UV–vis: ∼400 OG per a single star). The efficient dye encapsulation is due to the high concentration of quaternary ammonium cations in the core. The number of core-bound dyes

  具有聚（乙二醇）（PEG）基臂的阳离子缩合的微凝胶核星形聚合物被设计为单分子聚阳离子纳米胶囊（主体），以包裹和刺激响应性地释放亲水和阴离子染料（客体）在水中。通常，通过PEG大分子引发剂（1）与带有季铵阳离子的连接剂（2）的连接反应，可以高收率（> 90％）直接合成高阳离子收率的星形聚合物（核心阳离子：〜670 /星）。）在钌催化的活性自由基聚合中。通过紫外可见光谱分析，该星形聚合物有效地封装了各种携带磺酸根阴离子的亲水性染料（甲基橙：MO；橙G：OG；甲基蓝：MB）（紫外可见：每单颗星约400 OG）。有效的染料包封归因于核心中高浓度的季铵阳离子。核心结合染料的数量随核心结合阳离子的数量增加而增加。提出了核内染料的连接结构：一个OG分子的固定化涉及两个核内铵阳离子。此外，通过与NaCl水溶液进行离子交换，成功地实现了染料从阳离子缩合星形聚合物中的刺激响应性释放。