(2-Hydroxy-3-phenoxypropyl) propanoate | 170375-21-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (2-Hydroxy-3-phenoxypropyl) propanoate
• CAS: 170375-21-0
• 化学式: C₁₂H₁₆O₄
• 分子量: 224.257
• InChiKey: WTPIGOCSPFFYOB-UHFFFAOYSA-N

物化性质

• 沸点：
  367.9±27.0 °C(Predicted)
• 密度：
  1.136±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (2-Hydroxy-3-phenoxypropyl) propanoate 生成 (R)-3-phenoxy-1-propanoyloxy-2-propanol
  参考文献：
  名称：

  Lipase-catalysed resolution of 3-(aryloxy)-1,2-propanediol derivatives — Towards an improved active site model of Pseudomonas cepacia lipase (amano PS)

  摘要：

  A variety of 3-(aryloxy)-1,2-propanediol derivatives with different substituents on the aromatic ring or at the primary hydroxy group were used as substrates in a kinetic resolution by transesterification with vinyl acetate catalysed by lipase from Pseudomonas cepacia (Amano PS). Derivatives with substituents in the para-position of the aromatic ring were accepted as substrates and resolved with high enantioselectivity. The corresponding derivatives with substituents in the ortho-position were much worse substrates for lipase PS or even non-substrates if the substituent was sufficiently space-filling as found for the tert-butyl, phenyl, benzyl or benzoyl residue. Otherwise, if the primary hydroxy group was substituted by unbranched long-chain acyl residues very good substrates were resulting. In contrast, derivatives with sterically crowded residues at the primary hydroxy group such as the pivaloyl, tert-butyldimethylsilyl, methanesulfonyl, para-toluenesulfonyl or trityl groups were nonsubstrates for lipase PS.

  DOI：

  10.1016/0957-4166(95)00166-m
• 作为产物：
  描述：

  苯基缩水甘油醚 、 sodium proprionate 在 cerium(IV) triflate 、 sodium dodecyl-sulfate 作用下， 反应 5.0h， 以83%的产率得到(2-Hydroxy-3-phenoxypropyl) propanoate
  参考文献：
  名称：

  在 Ce(OTf)4 催化的胶束介质中具有羧酸盐和苯氧化物的环氧化物的开环

  摘要：

  摘要 环氧化物与羧酸根和苯氧根阴离子在三氟甲磺酸铈催化下的有效开环反应是在胶束介质中进行的。这种新方法是在温和的反应条件下由环氧化物制备 β-羧基和苯氧基醇的有用方法。

  DOI：

  10.1081/scc-120005998

文献信息

• ELECTROPHORETIC PARTICLES, ELECTROPHORETIC PARTICLE DISPERSION, DISPLAY MEDIUM AND DISPLAY DEVICE
  申请人：TOKUNAGA Nami

  公开号：US20110043441A1

  公开（公告）日：2011-02-24

  Electrophoretic particles including mother particles and a dispersant that covers the surface of the mother particles, the mother particles including a resin and a colorant, and the dispersant having a structure represented by the following Formula (1): wherein in Formula (1), R 1 represents a dimethyl siloxane chain that comprises two or more dimethyl siloxane structures that are linked together, the dimethyl siloxane chain being optionally substituted by an organic group; R 2 represents a hydrogen atom or a methyl group; Ar 1 represents an organic group having an aromatic group; a represents an integer of from 8 to 88; b represents an integer of from 12 to 82; c represents an integer of from 0 to 30; f represents an integer of from 1 to 3; the total of a, b and c is 100; and the ratio of unit (b) in the dispersant having a structure represented by Formula (1) is about 50% by weight or less.
• DISPLAY MEDIUM AND DISPLAY DEVICE
  申请人：MORIYAMA Hiroaki

  公开号：US20120068990A1

  公开（公告）日：2012-03-22

  A display medium includes a pair of substrates, a dispersion medium sealed between the pair of substrates, a migrating particle group dispersed in the dispersion medium, and a surface layer provided on at least one of the facing surfaces of the pair of substrates and including a polymer compound that is a copolymer containing the following constitutional unit (A) and constitutional unit (B): In the constitutional units (A) and (B), X represents a group containing a silicone chain, Ra 1 and Ra 2 each independently represent a hydrogen atom or a methyl group, Rb 2 represents an organic group containing a substituted or unsubstituted phenyl group, n1 and n2 each represent mold of the constitutional unit relative to the whole copolymer and satisfy 0
• US8581899B2
  申请人：——

  公开号：US8581899B2

  公开（公告）日：2013-11-12
• US8654070B2
  申请人：——

  公开号：US8654070B2

  公开（公告）日：2014-02-18
• RING OPENING OF EPOXIDES WITH CARBOXYLATES AND PHENOXIDES IN MICELLAR MEDIA CATALYZED WITH Ce(OTf)₄
  作者：N. Iranpoor、H. Firouzabadi、A. Safavi、M. Shekarriz

  DOI：10.1081/scc-120005998

  日期：2002.1

  ABSTRACT Efficient ring opening reaction of epoxides with carboxylates and phenoxide anions catalyzed with ceric triflate is performed in micellar media. This new method is a useful procedure for the preparation of β-carboxy and phenoxy alcohols from epoxides under mild reaction conditions.

  摘要 环氧化物与羧酸根和苯氧根阴离子在三氟甲磺酸铈催化下的有效开环反应是在胶束介质中进行的。这种新方法是在温和的反应条件下由环氧化物制备 β-羧基和苯氧基醇的有用方法。