Myristinsaeure-2-pentylester | 55195-14-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Myristinsaeure-2-pentylester
• 英文别名: Pentan-2-yl tetradecanoate
• CAS: 55195-14-7
• 化学式: C₁₉H₃₈O₂
• 分子量: 298.51
• InChiKey: GRYZSSDACMKIFV-UHFFFAOYSA-N

物化性质

• 沸点：
  340.7±10.0 °C(Predicted)
• 密度：
  0.862±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-戊醇 、 肉豆蔻酰氯 在 吡啶 作用下， 生成 Myristinsaeure-2-pentylester
  参考文献：
  名称：

  Schlenk,W., Justus Liebigs Annalen der Chemie, 1973, p. 1179 - 1194

  摘要：

  DOI：

文献信息

• Use of Lecitase-Ultra immobilized on styrene-divinylbenzene beads as catalyst of esterification reactions: Effects of ultrasounds
  作者：Joana S. Alves、Cristina Garcia-Galan、Daiane Danelli、Natália Paludo、Oveimar Barbosa、Rafael C. Rodrigues、Roberto Fernandez-Lafuente

  DOI：10.1016/j.cattod.2014.11.036

  日期：2015.10

  In this work it was evaluated for the first time, the ester synthesis catalyzed by the phospholipase Lecitase-Ultra immobilized styrene-divinylbenzene beads (MCI-Lecitase), comparing the mechanical stirring and the ultrasonic energy. It was studied the specificity of the enzyme using carboxylic acids from C4 to C18, as well as the effects of alcohol chain, organic solvents, biocatalyst content, reaction temperatureand substrate concentration. Caprylic and myristic acids were those with the highest reaction rates and yields, using ethanol as substrate. The shorter the alcohol chain, the higher the enzyme activity. Regarding the secondary alcohols, while MCI-Lecitase had no activity versus isopropanol, using 2-pentanol the activity was similar to that with 1-pentanol. Comparing the agitation systems, MCI-Lecitase presented an initial reaction rate more than 2-times higher in the ultrasound-assisted reaction than under traditional mechanical stirring. Moreover, under ultrasonic energy the maximum rate was achieved using 0.5 M of substrates, while under mechanical stirring the maximum enzyme activity was reached at 0.3 M of substrates. Concerning the operational stability, MCI-Lecitase was quite unstable, losing its activity after 6 reaction cycles. By adding molecular sieves in the reaction medium, MCI-Lecitase retained 30% of its initial activity after 6 cycles. (C) 2014 Elsevier B.V. All rights reserved.
• US6506486B1
  申请人：——

  公开号：US6506486B1

  公开（公告）日：2003-01-14
• Schlenk,W., Justus Liebigs Annalen der Chemie, 1973, p. 1179 - 1194
  作者：Schlenk,W.

  DOI：——

  日期：——