2-(4-Dodecoxyphenoxy)acetyl chloride | 55205-51-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(4-Dodecoxyphenoxy)acetyl chloride
• CAS: 55205-51-1
• 化学式: C₂₀H₃₁ClO₃
• 分子量: 354.917
• InChiKey: YRWOLGLDFWBOGA-UHFFFAOYSA-N

物化性质

• 沸点：
  440.9±20.0 °C(Predicted)
• 密度：
  1.031±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  24
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  三乙烯四胺 、 2-(4-Dodecoxyphenoxy)acetyl chloride 在 吡啶 、 4-二甲氨基吡啶 作用下， 以 氯仿 为溶剂， 以82%的产率得到2-(4-Dodecyloxy-phenoxy)-N-{2-[2-(4-dodecyloxy-phenoxy)-acetylamino]-ethyl}-N-[2-([2-(4-dodecyloxy-phenoxy)-acetyl]-{2-[2-(4-dodecyloxy-phenoxy)-acetylamino]-ethyl}-amino)-ethyl]-acetamide
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p
• 作为产物：
  描述：

  (4-Dodecyloxy-phenoxy)-acetic acid 在 草酰氯 、 N,N-二甲基甲酰胺 作用下， 以 氯仿 为溶剂， 反应 5.0h， 生成 2-(4-Dodecoxyphenoxy)acetyl chloride
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p

文献信息

• US3973979A
  申请人：——

  公开号：US3973979A

  公开（公告）日：1976-08-10
• First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction
  作者：Qi-Zhong Zhou、Xi-Kui Jiang、Xue-Bin Shao、Guang-Ju Chen、Mu-Xin Jia、Zhan-Ting Li

  DOI：10.1021/ol034549p

  日期：2003.5.1

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.