glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycine | 38416-68-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycine
• 英文别名: Glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycin；Heptaglycylglycin；Octaglycin；2-[[2-[[2-[[2-[[2-[[2-[[2-[(2-Aminoacetyl)amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetic acid
• CAS: 38416-68-1
• 化学式: C₁₆H₂₆N₈O₉
• 分子量: 474.431
• InChiKey: NHKXFOWSKYCOHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.8
• 重原子数：
  33
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  267
• 氢给体数：
  9
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycine 在 盐酸 、 sodium hydroxide 、 1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  Affinity electrophoresis in multisectional polyacrylamide slab gels is a useful and convenient technique for measuring binding constants of aryl sulfonamides to bovine carbonic anhydrase B

  摘要：

  This paper describes convenient preparations of heterogeneous multisectional polyacrylamide slab gels and the protocols that use these gels to measure protein-ligand binding constants [using bovine carbonic anhydrase B (CAB) as a model system]. Unlike procedures for affinity electrophoresis using tube gels, all binding information concerning protein-ligand interactions was encoded in a single multisectional gel: the procedure involving for measuring binding constants required no postelectrophoresis manipulation of gels. Use of these types of gels improves the accuracy of affinity gel electrophoresis (AGE) by providing reliable internal protein standards. Binding constants measured by AGE agree with those determined in homogeneous solution by spectrophotometric measurements. This technique has been used to investigate the influence of the length of the spacer separating the ligand and the polyacrylamide backbone on the binding constants. Dissociation constants obtained using the affinity gels approach the values measured in free solution, when the spacer is sufficiently long (greater-than-or-equal-to 18 angstrom); affinity ligands having short spacers give high apparent dissociation constants.

  DOI：

  10.1021/ac00058a004
• 作为产物：
  描述：

  glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycine 在 sodium hydroxide 、 氨 、 水 、 lithium bromide 作用下， 生成 glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycyl=>glycine
  参考文献：
  名称：

  Abderhalden; Heumann, Fermentforschung, 1931, vol. 12, p. 45

  摘要：

  DOI：

文献信息

• Mechanochemical Prebiotic Peptide Bond Formation**
  作者：Tomislav Stolar、Saša Grubešić、Nikola Cindro、Ernest Meštrović、Krunoslav Užarević、José G. Hernández

  DOI：10.1002/anie.202100806

  日期：2021.6

  still unclear as most oligomerization approaches rely on thermodynamically disfavored reactions in solution. Now, a combination of prebiotically plausible minerals and mechanochemical activation enables the oligomerization of glycine at ambient temperature in the absence of water. Raising the reaction temperature increases the degree of oligomerization concomitantly with the formation of a commonly

  益生元地球上存在的氨基酸，无论是源自内源性化学途径还是由陨石传递，都是公认的。由于大多数寡聚化方法依赖于溶液中的热力学不利反应，因此从灭活氨基酸到肽的益生元合理途径仍不清楚。现在，益生元似是而非的矿物质和机械化学活化的组合能够在无水的情况下在环境温度下进行甘氨酸寡聚化。升高反应温度会增加低聚度，同时形成通常不需要的环状甘氨酸二聚体 (DKP)。然而，DKP 是甘氨酸机械化学低聚中的生产中间体。
• Abderhalden; Neumann, Fermentforschung, 1933, vol. 13, p. 382,385, 392
  作者：Abderhalden、Neumann

  DOI：——

  日期：——
• CDNA SEQUENCE OF DENGUE VIRUS SEROTYPE 1 (SINGAPORE STRAIN)
  申请人：NATIONAL UNIVERSITY OF SINGAPORE

  公开号：EP0638122A1

  公开（公告）日：1995-02-15
• RIFAMYCIN BIOSYNTHESIS GENE CLUSTER
  申请人：Novartis AG

  公开号：EP0929681A1

  公开（公告）日：1999-07-21
• Silica Compositions
  申请人：Lalgudi Ramanathan S.

  公开号：US20140194341A1

  公开（公告）日：2014-07-10

  Compositions are provided, the compositions comprising: a silica compound containing at least one nitrogen atom; and a carboxylated polymer containing at least one nitrogen atom. The compositions may be useful to control algal growth, including harmful algal blooms (HAB).