(3-phenoxy-propyl)-malonic acid | 63258-09-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (3-phenoxy-propyl)-malonic acid
• 英文别名: 5-Phenoxy-2-carboxy-valeriansaeure；(3-Phenoxy-propyl)-malonsaeure；4-Phenoxy-butan-dicarbonsaeure-(1.1)；(γ-Phenoxy-propyl)-malonsaeure；(3-Phenoxypropyl)malonic acid；2-(3-phenoxypropyl)propanedioic acid
• CAS: 63258-09-3
• 化学式: C₁₂H₁₄O₅
• 分子量: 238.24
• InChiKey: NEAQOUUTPBNYKV-UHFFFAOYSA-N

物化性质

• 熔点：
  115-116 °C (decomp)
• 沸点：
  476.8±40.0 °C(Predicted)
• 密度：
  1.283±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (3-phenoxy-propyl)-malonic acid 在 乙醇 、 sodium 作用下， 生成 5-phenoxypentylamine
  参考文献：
  名称：

  Gabriel, Chemische Berichte, 1892, vol. 25, p. 421

  摘要：

  DOI：
• 作为产物：
  描述：

  3-苯氧基溴丙烷 在 sodium hydroxide 、 sodium ethanolate 作用下， 生成 (3-phenoxy-propyl)-malonic acid
  参考文献：
  名称：

  Carter, Journal of the American Chemical Society, 1928, vol. 50, p. 1969

  摘要：

  DOI：

文献信息

• [EN] N-ACETYLGALACTOSAMINE(GAlNAc)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES<br/>[FR] COMPOSÉS DÉRIVÉS DE N-ACÉTYLGALACTOSAMINE (GALNAC) ET OLIGONUCLÉOTIDES
  申请人：ADARX PHARMACEUTICALS INC

  公开号：WO2022076922A1

  公开（公告）日：2022-04-14

  Provided herein are N-acetylgalactosamine (GalNAc)-derived compounds, modified oligonucleotides, and methods of modulating protein function and treating diseases, disorders, and symptoms in a subject.

  本文提供了N-乙酰半乳糖胺（GalNAc）衍生化合物、修饰寡核苷酸以及在受体体内调节蛋白质功能、治疗疾病、疾患和症状的方法。
• Suberization of a polymeric sustain release matrix for animal repellancy
  申请人：——

  公开号：US20030202998A1

  公开（公告）日：2003-10-30

  The invention is an animal repellant composition containing one or more plant derived toxins, including for example one or more alkaloids isolated from for example, one or more members of the family Narcissus, and optionally containing one or more polymers, including for example one or more bioerodible polymers and/or more non-absorbable polymers. The animal repellant composition is useful for repelling animals from vegetation and for rendering vegetation unpalatable to animals. The invention also includes methods for repelling animals, as well as methods for treating vegetation to render the vegetation unpalatable to animals, such animals including for example, deer, voles, moles, ground hogs, mice, rats, rodents, raccoons, nematodes, larvae, worms, fungi, molds, bacteria, vegetative organisms, and insects. A suberin-polymer-repellant chemical complex and a method for treating damaged vegetation are also disclosed.

  本发明是一种动物驱避剂组合物，含有一种或多种植物提取的毒素，包括例如从水仙科的一种或多种植物中分离出来的一种或多种生物碱，还可选择含有一种或多种聚合物，包括例如一种或多种可生物降解的聚合物和/或更多不可吸收的聚合物。该动物驱避剂组合物可用于驱赶植被上的动物，并使植被变得对动物无味。本发明还包括驱赶动物的方法，以及处理植被使植被对动物难闻的方法，这些动物包括例如鹿、田鼠、鼹鼠、土猪、小鼠、大鼠、啮齿类动物、浣熊、线虫、幼虫、蠕虫、真菌、霉菌、细菌、植被生物和昆虫。此外，还公开了一种单宁-聚合物-斥力剂化学复合物和一种处理受损植被的方法。
• Compositions and methods of crop protection
  申请人：——

  公开号：US20040151750A1

  公开（公告）日：2004-08-05

  The invention is an animal repellant composition containing one or more toxins, including for example one or more alkaloids isolated from for example, one or more members of the family Narcissus, and optionally containing one or more polymers, including for example one or more bioerodible polymers and/or more non-absorbable polymers. The animal repellant composition is useful for repelling animals from vegetation and for rendering vegetation unpalatable to animals. The invention also includes methods for repelling animals, as well as methods for treating vegetation to render the vegetation unpalatable to animals, such animals including for example, deer, voles, moles, ground hogs, mice, rats, rodents, raccoons, nematodes, larvae, worms, fungi, molds, bacteria, vegetative organisms, and insects. A suberin-polymer-repellant chemical complex and a method for treating damaged vegetation are also disclosed. Various other systems and methods for complexing biopolymers, toxins, and polymers for treating plants, microbially inactivating the bioburden of vegetation, and for repelling animals are disclosed.

  本发明是一种动物驱避剂组合物，含有一种或多种毒素，包括例如从水仙家族的一种或多种成员中分离出来的一种或多种生物碱，还可选择含有一种或多种聚合物，包括例如一种或多种可生物降解的聚合物和/或更多不可吸收的聚合物。该动物驱避剂组合物可用于驱赶植被上的动物，并使植被变得对动物无味。本发明还包括驱赶动物的方法，以及处理植被使植被对动物难闻的方法，这些动物包括例如鹿、田鼠、鼹鼠、土猪、小鼠、大鼠、啮齿类动物、浣熊、线虫、幼虫、蠕虫、真菌、霉菌、细菌、植被生物和昆虫。此外，还公开了一种单宁-聚合物-斥力剂化学复合物和一种处理受损植被的方法。此外，还公开了用于处理植物、微生物灭活植被生物负载和驱赶动物的生物聚合物、毒素和聚合物复合物的各种其他系统和方法。
• Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials
  申请人：Eigen Peter

  公开号：US20050148702A1

  公开（公告）日：2005-07-07

  Compositions comprising a mineral oil or wax and a liquid polysiloxane substituted by functional groups, an anionic surfactant and additionally a molecular mono- or polycarboxylic acid and optionally any emulsifiable, hydrophilic or amphiphilic polymer comprising carboxyl groups are outstanding water repellents for leather, furskins, textiles and fibrous materials.

  由矿物油或蜡和被官能团取代的液态聚硅氧烷、阴离子表面活性剂以及单羧酸或多羧酸分子和可选的包含羧基的任何可乳化的亲水或两性聚合物组成的复合物是皮革、毛皮、纺织品和纤维材料的出色防水剂。
• 934. Chemical constitution and amoebicidal action. Part II. Synthesis of 2-(1 : 2 : 3 : 4-tetrahydro-6 : 7-dimethoxy-2-methyl-1-iso-quinolylmethyl)-1-(1 : 2 : 3 : 4-tetrahydro-6 : 7-dimethoxy-1-isoquinolyl)-butane and -pentane and other analogues of emetine
  作者：J. M. Osbond、J. D. Fulton、D. F. Spooner

  DOI：10.1039/jr9520004785

  日期：——