5-amino-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-pyrazole | 99676-90-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-amino-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-pyrazole
• 英文别名: 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazole；2-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazol-3-amine
• CAS: 99676-90-1
• 化学式: C₁₀H₆Cl₂F₃N₃
• 分子量: 296.079
• InChiKey: NXJCLNYWBFNGKR-UHFFFAOYSA-N

物化性质

• 沸点：
  356.0±42.0 °C(Predicted)
• 密度：
  1.63±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5-amino-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-pyrazole 生成 5-chloromethanesulphonamido-1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazole
  参考文献：
  名称：

  摘要：

  DOI：
• 作为产物：
  描述：

  2,6-二氯-4-三氟甲基苯肼 、 trans-3-Chlor-acrylnitril 生成 5-amino-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-pyrazole
  参考文献：
  名称：

  SCHALLER, O.;GEHRING, R.;KLANKE, E.;STETTER, JO.;WROBLOWSKY, H. -JU.;SCHM+

  摘要：

  DOI：

文献信息

• Pest-combating agents based on pyrazole derivatives
  申请人：Bayer Aktiengesellschaft

  公开号：US04945165A1

  公开（公告）日：1990-07-31

  A 5-aminopyrazole of the formula (I) ##STR1## in which R.sup.2 represents CF.sub.3 or CCL.sub.2 F, R.sup.3 represents hydrogen or CH.sub.3 and n represents the number 0 or 1. The 5-aminopyrazole of formula (I) is effective in combating insects, sense animals and nematodes.

  式(I)的5-氨基吡唑##STR1##其中R.sup.2代表CF.sub.3或CCL.sub.2 F，R.sup.3代表氢或CH.sub.3，n代表数字0或1。式(I)的5-氨基吡唑对抗昆虫、感官动物和线虫有效。
• 4-haloalkylthio-5-amino-1-arylpyrazoles, composition containing them,
  申请人：Bayer Aktiengesellschaft

  公开号：US04771066A1

  公开（公告）日：1988-09-13

  Insecticidally and acarididally active 1-arylpyrazoles of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl or halogen alkyl, R.sup.2 represents alkyl, alkenyl, alkinyl, cycloalkyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, alkylsulphinylalkyl, alkylsulphonylalkyl, optionally substituted aralkyl or optionally substituted aryl, R.sup.3 represents alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aralkyl, R.sup.4 represents alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aralkyl, and, in addition, also represents hydrogen in the case where R.sup.3 does not simultaneously represent unsubstituted alkyl, or R.sup.3 and R.sup.4, together with the nitrogen atom to which they are bound, represent a saturated heterocycle, which can optionally contain further heteroatoms, Ar represents in each case optionally substituted phenyl or pyridyl, and n represents a number 0, 1 or 2.

  杀虫杀螨活性的1-芳基吡唑的化学式为##STR1##其中R.sup.1代表氢、烷基或卤代烷基，R.sup.2代表烷基、烯基、炔基、环烷基、卤代烷基、卤代烯基、烷氧基烷基、烷硫基烷基、烷基亚砜基烷基、烷基砜基烷基、可选择取代的芳基烷基或可选择取代的芳基，R.sup.3代表烷基、烯基、炔基、卤代烷基、卤代烯基、烷氧基烷基、烷硫基烷基、环烷基或可选择取代的芳基烷基，R.sup.4代表烷基、烯基、炔基、卤代烷基、卤代烯基、烷氧基烷基、烷硫基烷基、环烷基或可选择取代的芳基烷基，另外，当R.sup.3不同时代表未取代的烷基时，R.sup.4也可以代表氢，或者R.sup.3和R.sup.4连同它们连接的氮原子一起代表饱和杂环，该杂环可以选择性地包含进一步的杂原子，Ar在每种情况下代表可选择取代的苯或吡啶，n代表数字0、1或2。
• 1-aryl-4-alkylthiopyrazol-5-amine derivatives, composition containing
  申请人：Bayer Aktiengesellschaft

  公开号：US04804675A1

  公开（公告）日：1989-02-14

  A method of combating insects, sense animals and nematodes comprising applying to insects, arachnids and nematodes and/or their environment an effective amount of at least one 5-aminopyrazole of the formula (I) ##STR1## in which R.sup.1 represents hydrogen, alkyl or halogenoalkyl, R.sup.2 represents alkyl, halogenoalkyl, unsubstituted or substituted aralkyl or unsubstituted or substituted aryl, R.sup.3 represents hydrogen, alkyl or a radical ##STR2## Ar represents unsubstituted or substituted phenyl or unsubstituted or substituted pyridyl and n represents the number 0, 1 or 2, wherein X represents oxygen or sulphur and R.sup.4 represents hydrogen, alkyl, alkenyl, alkinyl, halogenoalkyl, alkoxyalkyl, alkylthioalkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl, alkoxy, alkylthio, unsubstituted or substituted aryloxy, unsubstituted or substituted arylthio, alkylamino, dialkylamino or unsubstituted or substituted arylamino.

  一种对抗昆虫、感知动物和线虫的方法，包括向昆虫、蜘蛛、线虫和/或它们的环境施加至少一种式(I)的有效量的5-氨基吡唑化合物，其中R.sup.1代表氢、烷基或卤代烷基，R.sup.2代表烷基、卤代烷基、未取代或取代的芳基烷基或未取代或取代的芳基，R.sup.3代表氢、烷基或基团，Ar代表未取代或取代的苯基或未取代或取代的吡啶基，n代表数字0、1或2，其中X代表氧或硫，R.sup.4代表氢、烷基、烯烷基、炔烷基、卤代烷基、烷氧基烷基、烷基硫基烷基、未取代或取代的环烷基、未取代或取代的芳基、烷氧基、烷基硫基、未取代或取代的芳氧基、未取代或取代的芳硫基、烷基氨基、二烷基氨基或未取代或取代的芳基氨基。
• 5-Heterocyclyl-1-aryl-pyrazoles, composition containing them, and method
  申请人：Bayer Aktiengesellschaft

  公开号：US04803215A1

  公开（公告）日：1989-02-07

  Pesticidally active 5-heterocyclyl-1-aryl-pyrazoles of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl or haloalkyl, R.sup.2 represents alkyl, alkenyl, alkinyl, cycloalkyl, haloalkyl, haloalkenyl, optionally substituted aralkyl or optionally substituted aryl, Ar represents in each case optionally substituted phenyl or pyridyl, Het represents a heterocycle of the formula ##STR2## n represents a number 0, 1 or 2, where R.sup.3 and R.sup.4, independently of one another, represent in each case hydrogen, alkyl or phenyl. Intermediates of the formulas ##STR3## are provided, the former also being pesticidal.

  化学式为##STR1##的具有杀虫活性的5-杂环基-1-芳基-吡唑酮，其中R.sup.1代表氢、烷基或卤代烷基，R.sup.2代表烷基、烯基、炔基、环烷基、卤代烷基、卤代烯基、可选地取代的芳基烷基或可选地取代的芳基，Ar在每种情况下代表可选取代的苯基或吡啶基，Het代表化学式##STR2##的杂环，n代表数字0、1或2，其中R.sup.3和R.sup.4，彼此独立地，在每种情况下代表氢、烷基或苯基。提供了化学式##STR3##的中间体，前者也具有杀虫活性。
• 1-aryl-pyrazoles, pesticidal compositions and use
  申请人：Bayer Aktiengesellschaft

  公开号：US04820725A1

  公开（公告）日：1989-04-11

  1-Aryl-pyrazole of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl or halogenoalkyl, R.sup.2 represents alkyl, halogenoalkyl or in each case optionally substituted aralkyl or aryl, R.sup.3 represents hydrogen or halogen, Ar represents optionally substituted phenyl or pyridyl, and n represents the number 0, 1 or 2, the 1-aryl-pyrazole being useful in agents for combating pests.

  公式为##STR1##的1-芳基吡唑化合物，其中R.sup.1代表氢、烷基或卤代烷基，R.sup.2代表烷基、卤代烷基或在每种情况下可选择地取代的芳基烷基或芳基，R.sup.3代表氢或卤素，Ar代表可选择地取代的苯基或吡啶基，n代表数字0、1或2，该1-芳基吡唑化合物在用于防治害虫的药剂中有用。