2-octoxy-2-oxoacetic acid | 57727-00-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-octoxy-2-oxoacetic acid
• 英文别名: octyl oxalate；Monooctyloxalat
• CAS: 57727-00-1
• 化学式: C₁₀H₁₈O₄
• 分子量: 202.251
• InChiKey: LGHDZIOWPVFVNB-UHFFFAOYSA-N

物化性质

• 沸点：
  301.3±25.0 °C(predicted)
• 密度：
  1.054±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-heptoxy-2-oxoacetic acid;2-methylpropan-2-amine 、 2-octoxy-2-oxoacetic acid 生成 2-methylpropan-2-amine;2-octoxy-2-oxoacetic acid
  参考文献：
  名称：

  PETYUNIN G. P., FARMATSEVTICHNIJ ZH., 1980, HO 3, 40-2

  摘要：

  DOI：
• 作为产物：
  描述：

  草酰氯 、 辛醇 以 乙醚 为溶剂， 生成 2-octoxy-2-oxoacetic acid
  参考文献：
  名称：

  用醇对嘌呤和嘌呤核苷进行轻质、无金属区域选择性 C6-H 烷基化

  摘要：

  以草酸盐为烷基自由基源，以易得的醇（1°、2°、3°）实现了嘌呤和核苷的金属、光自由基烷基化反应，不需要任何催化剂、N 2保护和保护基团。尽管嘌呤基序中存在3个潜在的活性C( sp 2 )  H键和4个干扰氮原子，但该反应在C 6  H位上仍然表现出优异的区域选择性，并且不存在多烷基化问题。此外，该方法表现出广泛的功能组耐受性，并且可扩展至克级，可应用于后期 C 嘌呤的 H 烷基化合成具有抗 CEM 活性的 6-环戊基星云碱，从而证明了其实用性。

  DOI：

  10.1002/jhet.4659

文献信息

• Method of producing nanoparticle suspensions
  申请人：Engel Robert

  公开号：US09296685B2

  公开（公告）日：2016-03-29

  Method of producing a nanoparticle suspension with the steps (i) preparation of an emulsion of a disperse polar phase, where the aqueous phase comprises one or more precursor substances forming the nanoparticles, in a continuous organic phase in the presence of an emulsifier stabilizing the emulsion, (ii) conversion of the one or more precursor substances to nanoparticles in the disperse aqueous phase, (iii) breaking of the emulsion and phase separation, where the nanoparticle suspension is obtained as one phase, (iv) separation off of the nanoparticle suspension, (v) optionally isolation of the nanoparticles from the nanoparticle suspension, wherein the emulsifier is selected from compounds of the general formula (I) in which X is O, NH, Y is C(O), NH, R is a saturated or a mono- or polyunsaturated, linear or branched hydrocarbon radical having 6 to 30 carbon atoms and R1 is hydrogen or C1-C4-alkyl, and R2 is a saturated or a mono- or polyunsaturated, linear or branched hydrocarbon radical having 1 to 30 carbon atoms, preferably 6 to 30 carbon atoms, R3 is C1-C4-alkyl, n is 0 or 1, and the breaking of the emulsion is effected by splitting the emulsifier.

  生产纳米粒子悬浮液的方法包括以下步骤：(i) 准备分散极性相的乳液，其中水相包括形成纳米粒子的一个或多个前体物质，在连续的有机相中存在一种稳定乳液的乳化剂，(ii) 将一个或多个前体物质转化为纳米粒子在分散水相中，(iii) 打破乳液并相分离，从而得到纳米粒子悬浮液作为一个相，(iv) 分离出纳米粒子悬浮液，(v) 可选地从纳米粒子悬浮液中分离纳米粒子，其中乳化剂选择自以下通式(I)的化合物，其中X为O、NH，Y为C(O)、NH，R为具有6到30个碳原子的饱和或单烯烃、线性或支链烃基，R1为氢或C1-C4-烷基，R2为具有1到30个碳原子的饱和或单烯烃、线性或支链烃基，优选为6到30个碳原子，R3为C1-C4-烷基，n为0或1，乳化剂的打破通过分解乳化剂来实现。
• PROCESS FOR PREPARING IONIC LIQUIDS BY ANION EXCHANGE
  申请人：Massonne Klemens

  公开号：US20100217010A1

  公开（公告）日：2010-08-26

  Process for preparing salts of the formula I (B + ) n x A y− where B is a cation comprising at least one nitrogen atom, A is an anion and n is an integer from 1 to 3, x and y are each an integer from 1 to 3 and the product of x and y is equal to n, by reacting salts of the formula II (B + ) n x A y− where B and n, x and y are as defined above and C is a compound which has one or more carboxylate groups (referred to as carboxylate for short) and is different from A, with the ammonium salt of the anion A or with the protic acid of the anion A in the presence of ammonia.

  制备I(B+)nxAy的盐的过程-其中B是至少含有一个氮原子的阳离子，A是阴离子，n是1到3的整数，x和y分别是1到3的整数，且x和y的乘积等于n，通过反应II(B+)nxAy的盐来实现-其中B和n、x和y如上定义，C是一种具有一个或多个羧酸基团（简称为羧酸）且与A不同的化合物，与阴离子A的铵盐或其质子酸在氨的存在下反应。
• Carboxylate and heat-sensitive recording material using same
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0679640A1

  公开（公告）日：1995-11-02

  A carboxylate is herein disclosed which is represented by the formula (1) or (2) wherein a ring X is an aromatic residue which may have a substituent; A is =NH or -(OR³ or OR⁴) (wherein each of R³ and R⁴ is independently an alkyl group having 1 to 8 carbon atoms which may have a substituent, and R³ and R⁴ may bond to each other to form a ring); R¹ is a hydrogen atom, an alkyl group having 1 to 20 carbon atoms which may have a substituent, an aralkyl group which may have a substituent, or an aryl group which may have a substitutent, but when A is =NH, R¹ is an aryl group which may have a substituent; and R² is an alkyl group having 1 to 8 carbon atoms which may have a substituent. A heat-sensitive recording material comprising this carboxylate is excellent in the stability of the color image and can provide an optically character-readable sharp color image.

  本文公开了一种羧酸盐，由式（1）或（2）表示 其中环 X 是可具有取代基的芳香残基；A 是＝NH 或-(OR³ 或 OR⁴)（其中 R³ 和 R⁴ 各自独立地是具有 1 至 8 个碳原子的烷基，可具有取代基，且 R³ 和 R⁴ 可相互键合形成环）；R¹是氢原子、具有 1 至 20 个碳原子的烷基（可带有取代基）、芳烷基（可带有取代基）或芳基（可带有取代基），但当 A =NH 时，R¹是芳基（可带有取代基）；以及 R² 是具有 1 至 8 个碳原子的烷基（可带有取代基）。由这种羧酸盐组成的热敏记录材料在彩色图像的稳定性方面非常出色，可以提供光学字符可读的清晰彩色图像。
• Use of chemiluminescence in cosmetics & chromatography
  申请人：Vaidya Ashok Niteen

  公开号：US20050118123A1

  公开（公告）日：2005-06-02

  Cosmetic composition consists of precursors for chemiluminescence's system is documented with novel use in hair dyes, lipsticks, sunscreen, sunblock and sunless tanning, skin brightening agents. In other application namely chromatography (experimental technique) use of chemiluminescence would make it unnecessary to use black/UV light to observe and detect chemicals in TLC (Thin layer chromatography).

  化妆品成分由化学发光系统的前体组成，在染发剂、口红、防晒霜、防晒油和防晒剂、皮肤增白剂中都有新的应用。在其他应用领域，即色谱法（实验技术）中，使用化学发光就无需使用黑光/紫外光来观察和检测 TLC（薄层色谱法）中的化学物质。
• Five-membered ring systems with bonded azacyclic ring substituents
  申请人：MERCK SHARP & DOHME LTD.

  公开号：EP0328200B1

  公开（公告）日：1993-12-08