3-(3,5-dibromo-4-nitro-1H-pyrazol-1-yl)propan-1-ol | 452082-34-7

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 3-(3,5-dibromo-4-nitro-1H-pyrazol-1-yl)propan-1-ol
• 英文别名: 3-(3,5-dibromo-4-nitropyrazol-1-yl)propan-1-ol
• CAS: 452082-34-7
• 化学式: C₆H₇Br₂N₃O₃
• 分子量: 328.948
• InChiKey: AXQAZBXMZVCAOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  83.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-(3,5-dibromo-4-nitro-1H-pyrazol-1-yl)propan-1-ol 、 苄胺 在 氯化钠 、 Sodium sulfate-III 、 ethyl acetate n-hexane 作用下， 以 乙醇 为溶剂， 反应 15.0h， 以an orange-colored oil was obtained (13.6 g), which的产率得到3-[5-(benzylamino)-3-bromo-4-nitro-1H-pyrazol-1-yl]propan-1-ol
  参考文献：
  名称：

  Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres

  摘要：

  本发明涉及具有以下式（I）的新型二氨基吡唑化合物：其中R1代表线性或支链C4-C5烷基或n-丙基基团，或线性或支链C3-C5单或多羟基烷基团，以及其与生理上可接受的酸的加成盐。本发明还涉及含有这种化合物的组合物，用于染色角蛋白纤维以及使用该组合物的方法。

  公开号：

  US07285136B2
• 作为产物：
  描述：

  3,5-二溴-4-硝基吡唑 、 3-溴-1-丙醇 在 sodium acetate 作用下， 以 N-甲基吡咯烷酮 为溶剂， 反应 5.0h， 以75%的产率得到3-(3,5-dibromo-4-nitro-1H-pyrazol-1-yl)propan-1-ol
  参考文献：
  名称：

  [EN] COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE
  [FR] COMPOSITION POUR LA COLORATION DE FIBRES DE KÉRATINE COMPRENANT AU MOINS UN DÉRIVÉ DE DIAMINO-N,N-DIHYDROPYRAZOLONE CATIONIQUE

  摘要：

  本发明的一个主题是一种用于染色角蛋白纤维，特别是人类角蛋白纤维（如头发）的组合物，其中包括至少一种式（I）的阳离子二氨基-N，N-二氢吡唑酮衍生物作为氧化基，并使用该方法。同样，一个主题是阳离子氨基-N，N-二氢吡唑酮衍生物或其加成盐。本发明特别可以获得一种持久的、耐光的和耐洗的角蛋白纤维染色。

  公开号：

  WO2009098257A1

文献信息

• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer
  申请人：Saunier Jean-Baptiste

  公开号：US20060277693A1

  公开（公告）日：2006-12-14

  The present disclosure relates to a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone compounds and addition salts thereof, at least one coupler and at least one associative polyurethane polymer, and also to a dyeing process and kit using such a composition. The present disclosure makes it possible, for instance, to obtain fast coloration of keratin fibers that is resistant to light and to washing.

  本公开涉及一种用于染色角蛋白纤维的组合物，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮化合物及其盐的氧化碱、至少一种偶联剂和至少一种缔合型聚氨酯聚合物，以及使用这种组合物的染色过程和套件。本公开使得例如可以获得对光线和水洗具有抗性的角蛋白纤维的快速着色。
• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one surfactant
  申请人：Saunier Jean-Baptiste

  公开号：US20060277692A1

  公开（公告）日：2006-12-14

  Disclosed herein is a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolones and the addition salts thereof, at least one coupler, and at least one surfactant chosen from (C 8 -C 30 )alkyl ether carboxylic acids and salts thereof, (C 12 -C 30 )alkyl polyglucosides, monoglycerolated surfactants, and polyglycerolated surfactants. Also disclosed herein is a method for dyeing keratin fibers comprising applying a composition in accordance with the present disclosure to the keratin fibers. The compositions and methods of the present disclosure may makes it possible to obtain fast coloration of keratin fibers that is resistant to light and/or to washing.

  本文揭示了一种用于染色角蛋白纤维的配方，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮和其盐的氧化碱，至少一种偶联剂，以及至少选择自（C8-C30）烷基醚羧酸及其盐，（C12-C30）烷基聚葡糖苷，单甘油酯表面活性剂和聚甘油酯表面活性剂的表面活性剂。本文还揭示了一种染色角蛋白纤维的方法，包括将根据本公开的配方应用于角蛋白纤维。本公开的配方和方法可以实现对角蛋白纤维进行快速染色，且具有抗光和/或洗涤的特性。
• Composition for dyeing keratin fibers, comprising a diamino-N,N-dihydropyrazolone compound, a coupler, and a polyol
  申请人：Saunier Jean-Baptiste

  公开号：US20060277691A1

  公开（公告）日：2006-12-14

  The present disclosure relates to a composition for dyeing keratin fibers, for instance human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone compounds and addition salts thereof, at least one coupler and at least one C 4 -C 30 polyol. The present disclosure also relates to the dyeing process and kit using the composition as presently disclosed. Use of the present disclosure makes it, for example, possible to obtain fast coloration of keratin fibers that is resistant to light and to washing.

  本公开涉及一种用于染色角蛋白纤维的组合物，例如人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮化合物及其盐的氧化碱、至少一种偶联剂和至少一种C4-C30多元醇。本公开还涉及使用所述组合物的染色过程和套件。例如，使用本公开可以实现对角蛋白纤维的快速着色，且具有抗光和抗洗的特性。
• Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative
  申请人：Vidal Laurent

  公开号：US20050166335A1

  公开（公告）日：2005-08-04

  Disclosed herein are a composition for dyeing keratinous fibers, for example, human keratinous fibers such as hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolone derivative and a method using the composition. Further disclosed herein are amino-N,N-dihydropyrazolone derivatives and the addition salts thereof and diamino-N,N-dihydropyrazolone derivatives and the addition salts thereof, as well as the methods for preparing these compounds.

  本文公开了一种用于染色角蛋白纤维的组合物，例如，人类角蛋白纤维，如头发，包括至少选择自二氨基-N，N-二氢吡唑酮衍生物的氧化碱和使用该组合物的方法。此外，本文还公开了氨基-N，N-二氢吡唑酮衍生物及其盐和二氨基-N，N-二氢吡唑酮衍生物及其盐，以及制备这些化合物的方法。
• Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler, and at least one heterocyclic direct dye
  申请人：Hercouet Leila

  公开号：US20070006398A1

  公开（公告）日：2007-01-11

  Disclose herein is a composition for dyeing keratin fibers, for example, human keratin fibers such as the hair, comprising at least one oxidation base chosen from diamino-N,N-dihydropyrazolones and addition salts thereof, at least one coupler, and at least one heterocyclic direct dye. Also disclosed herein is a method for dyeing keratin fibers comprising applying a composition of the present disclosure to the keratin fibers. The compositions and methods of the present disclosure may make it possible to obtain fast coloration of keratin fibers that is resistant to light and/or to washing.

  本文披露了一种用于染色角蛋白纤维的组合物，例如，人类角蛋白纤维如头发，包括至少选择自二氨基-N，N-二氢吡唑酮和其盐中的至少一种氧化碱，至少一种偶联剂，以及至少一种杂环直接染料。本文还披露了一种染色角蛋白纤维的方法，包括将本文所述的组合物应用于角蛋白纤维。本文所披露的组合物和方法可能使得能够获得对光线和/或洗涤具有抗性的角蛋白纤维的快速着色。