3-aza-3-benzyl-1,5-diphenylpentane-1,5-diol (rac) | 183015-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-aza-3-benzyl-1,5-diphenylpentane-1,5-diol (rac)
• 英文别名: 2-[Benzyl-(2-hydroxy-2-phenylethyl)amino]-1-phenylethanol
• CAS: 183015-05-6
• 化学式: C₂₃H₂₅NO₂
• 分子量: 347.457
• InChiKey: UCNCUQNDNPWJTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  43.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-aza-3-benzyl-1,5-diphenylpentane-1,5-diol (rac) 、 lithium aluminium tetrahydride 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  Manickam; Sundararajan, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997, vol. 36, # 6, p. 516 - 518

  摘要：

  DOI：
• 作为产物：
  描述：

  氧化苯乙烯 、 苄胺 在 C₁₀₀O₃₉H₁₂*5H₂O 作用下， 以 neat (no solvent) 为溶剂， 反应 48.0h， 以64%的产率得到3-aza-3-benzyl-1,5-diphenylpentane-1,5-diol (rac)
  参考文献：
  名称：

  Catalytic activity of graphite-based nanofillers on cure reaction of epoxy resins

  摘要：

  The strong influence of graphite oxide (GO) nanofiller on the glass transition temperature (T-g) of epoxy resins, generally attributed to restricted molecular mobility of the epoxy matrix by the nanofiller or to the crosslinking of GO layers via the epoxy chains, is investigated. The study confirms that large increases of the glass transition temperature of the nanocomposite can be observed in presence of GO. However, similar T-g increases are observed, when the filler is a high-surface-area graphite (HSAG), lacking oxidized groups. Moreover, these T-g differences tend to disappear as a consequence of aging or thermal annealing. These results suggest that the observed T-g increases are mainly due to a catalytic activity of graphitic layers on the crosslinking reaction between the epoxy resin components (epoxide oligomer and diamine), rather than to reaction of the epoxide groups with functional groups of GO. This hypothesis is supported by investigating the catalytic activity of graphite-based materials on reactions between analogous monofunctional epoxide and amine compounds. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2014.09.019
• 作为试剂：
  描述：

  苄叉丙酮 、 丙二酸二乙酯 在 lithium aluminium tetrahydride 、 3-aza-3-benzyl-1,5-diphenylpentane-1,5-diol (rac) 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 以95%的产率得到ethyl 2-ethoxycarbonyl-5-oxo-3-phenylhexanoate
  参考文献：
  名称：

  Manickam; Sundararajan, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997, vol. 36, # 6, p. 516 - 518

  摘要：

  DOI：

文献信息

• Manickam; Sundararajan, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996, vol. 35, # 10, p. 1006 - 1011
  作者：Manickam、Sundararajan

  DOI：——

  日期：——
• [EN] PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF OPTICALLY ACTIVE 3-AMINO-1-(2-THIENYL)-1-PROPANOL DERIVATIVES<br/>[FR] PROCEDES ET PRODUITS INTERMEDIAIRES POUR LA PREPARATION DE DERIVES DE 3-AMINO-1-(2-THIENYL)-1-PROPANOL OPTIQUEMENT ACTIFS
  申请人：LONZA AG

  公开号：WO2004031168A2

  公开（公告）日：2004-04-15

  Enantiomerically enriched 3-amino-1-(2-thienyl)-1-propanols of the formulae ((S)-I) or ((R)-I) wherein R1 and R2 independently denote H, C1-6-alkyl, C5-7-cycloalkyl, aralkyl or aryl, were prepared by reducing a 3-amino-1-(2-thienyl)-1-propanone of the formula (II) wherein R1 and R2 are defined as above, using a hydrogen donor in the presence of a metal catalyst, an optically active nitrogen-containing ligand and optionally a base.
• Manickam; Sundararajan, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997, vol. 36, # 6, p. 516 - 518
  作者：Manickam、Sundararajan

  DOI：——

  日期：——
• Catalytic activity of graphite-based nanofillers on cure reaction of epoxy resins
  作者：Marco Mauro、Maria Rosaria Acocella、Carola Esposito Corcione、Alfonso Maffezzoli、Gaetano Guerra

  DOI：10.1016/j.polymer.2014.09.019

  日期：2014.10

  The strong influence of graphite oxide (GO) nanofiller on the glass transition temperature (T-g) of epoxy resins, generally attributed to restricted molecular mobility of the epoxy matrix by the nanofiller or to the crosslinking of GO layers via the epoxy chains, is investigated. The study confirms that large increases of the glass transition temperature of the nanocomposite can be observed in presence of GO. However, similar T-g increases are observed, when the filler is a high-surface-area graphite (HSAG), lacking oxidized groups. Moreover, these T-g differences tend to disappear as a consequence of aging or thermal annealing. These results suggest that the observed T-g increases are mainly due to a catalytic activity of graphitic layers on the crosslinking reaction between the epoxy resin components (epoxide oligomer and diamine), rather than to reaction of the epoxide groups with functional groups of GO. This hypothesis is supported by investigating the catalytic activity of graphite-based materials on reactions between analogous monofunctional epoxide and amine compounds. (C) 2014 Elsevier Ltd. All rights reserved.