2-methyl-3-pentyl acetate | 35897-16-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-methyl-3-pentyl acetate
• 英文别名: acetic acid-(1-ethyl-2-methyl-propyl ester)；Essigsaeure-(1-aethyl-2-methyl-propylester)；2-methyl-3-pentanol, acetate；3-acetoxy-2-methylpentane；2-Methylpentan-3-yl acetate
• CAS: 35897-16-6
• 化学式: C₈H₁₆O₂
• 分子量: 144.214
• InChiKey: GLESBSXIWORDRL-UHFFFAOYSA-N

物化性质

• 沸点：
  144.4±8.0 °C(Predicted)
• 密度：
  0.874±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915390090

反应信息

• 作为产物：
  描述：

  异丁醛 在 乙酸酐 作用下， 以 正己烷 、 甲苯 为溶剂， 以100%的产率得到2-methyl-3-pentyl acetate
  参考文献：
  名称：

  Catalysts for asymmetric addition of organozinc reagents to aldehydes and method for preparation

  摘要：

  提供了新型手性氨醇催化剂及其制备方法。第一种催化剂是通过对前体中的两个苯环中的一个进行选择性氢化制备的。氨醇促进有机锌试剂对醛的不对称加成，以得到光学活性醇或其酯。第二种催化剂是通过3-外共轭氨基异藁醇与2-卤乙基醚的选择性二烷基化制备的。氨醇促进对含有β-支链的脂肪族醛的有机锌试剂的加成，相对于DAIB具有大大增强的对映选择性。

  公开号：

  US06187918B1

文献信息

• Catalysts for asymmetric addition of organozinc regents to aldehydes and method for preparation
  申请人：Bristol-Myers Squibb Pharma Company

  公开号：US06362344B1

  公开（公告）日：2002-03-26

  Chiral aminoalcohol catalysts and methods for their preparation are provided. The first catalyst is prepared via selective hydrogenation of one of two benzene rings in a precursor. The aminoalcohol promotes the asymmetric addition of organozinc reagents to aldehydes to afford optically active alcohols or their esters. The second catalyst is prepared by selective dialkylation of 3-exo-aminoisoborneol with a 2-haloethyl ether. The aminoalcohol promotes the addition of organozinc reagents to aliphatic aldehydes containing a &bgr;-branch with greatly enhanced enantioselectivity relative to DAIB.

  提供手性氨醇催化剂及其制备方法。第一种催化剂是通过选择性氢化前体中的两个苯环之一制备的。氨醇促进有机锌试剂对醛的不对称加成，生成光学活性醇或其酯。第二种催化剂是通过选择性对3-外氨基异螺烷基与2-卤乙基醚进行二烷基化制备的。氨醇促进对含有β-支链的脂肪族醛的有机锌试剂加成，相对于DAIB具有大大增强的对映选择性。
• PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE
  申请人：Heffernan Michele L. R.

  公开号：US20110034434A1

  公开（公告）日：2011-02-10

  The invention relates to prodrugs of fused heterocyclic inhibitors of D-amino oxidase (DAAO) and methods of treating diseases and conditions, wherein modulation of D-amino acid oxidase activity, D-serine levels, D-serine oxidative products and NMDA receptor activity in the nervous system of a mammalian subject is effective.

  该发明涉及融合杂环抑制剂的前药，用于治疗疾病和病况的方法，其中在哺乳动物主体的神经系统中调节D-氨基酸氧化酶活性、D-丝氨酸水平、D-丝氨酸氧化产物和NMDA受体活性是有效的。
• Second-Generation Paracyclophane Imine Ligands for the Dialkylzinc Addition to Aldehydes. Optimization of the Branched Side Chain leads to Improvement for Aliphatic Aldehydes
  作者：Sebastian Höfener、Frank Lauterwasser、Stefan Bräse

  DOI：10.1002/adsc.200404068

  日期：2004.6

  diastereomeric [2.2]paracyclophane ketimine ligands (SP,S)-2 and (RP,S)-2, which unite a planar chiral element and a central chiral element, were used towards the enantioselective diethylzinc addition onto aliphatic aldehydes. These improved second-generation ligands, which are stable in air and water and are easy to obtain, showed significant improvements with respect to the ligands that were previously

  两个新的非对映异构的[2.2]对环phane酮亚胺配体（S P，S）-2和（R P，S）-2，将平面手性元素和中心手性元素结合在一起，用于将对映选择性二乙基锌加成到脂肪族醛上。这些改进的第二代配体在空气和水中均稳定并且易于获得，相对于先前使用的配体而言，显示出显着的改进。
• Method of preparing alkoxylation catalysts and their use in alkoxylation processes
  申请人：Weerasooriya Peter Upali

  公开号：US20050240064A1

  公开（公告）日：2005-10-27

  A process for preparing an alkoxylation catalyst suitable for alkoxylating compounds that includes mixing a calcium-containing compound in a dispersing medium having a boiling point less that 160° C. with a carboxylic acid and an inorganic acid or anhydride.

  一种制备适用于烷氧基化化合物的烷氧基化催化剂的方法，包括将含钙化合物与羧酸和无机酸或酐混合于沸点低于160°C的分散介质中。
• Process For Making Fatty Amides
  申请人：Weerasooriya Upali

  公开号：US20110092715A1

  公开（公告）日：2011-04-21

  A process for reacting, in the presence of a particular calcium containing catalyst, an amine having an active hydrogen and one or more of a fatty acid ester or a fatty acid.

  在特定含钙催化剂的存在下，反应一种具有活性氢的胺和一种或多种脂肪酸酯或脂肪酸的过程。