5-[(4-bromophenyl)methyl]-2-(2-methylphenyl)-5H-imidazo[4,5-c]pyridine | 928006-54-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-[(4-bromophenyl)methyl]-2-(2-methylphenyl)-5H-imidazo[4,5-c]pyridine
• 英文别名: 5-[(4-Bromophenyl)methyl]-2-(o-tolyl)imidazo[4,5-c]pyridine；5-[(4-bromophenyl)methyl]-2-(2-methylphenyl)imidazo[4,5-c]pyridine
• CAS: 928006-54-6
• 化学式: C₂₀H₁₆BrN₃
• 分子量: 378.271
• InChiKey: DXXPTYBMAGNSPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Viral inhibitors
  申请人：Neyts Johan

  公开号：US20050239821A1

  公开（公告）日：2005-10-27

  The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine derivative having the general formula (Z): (formula). The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections.

  本发明涉及一种用于治疗或预防病毒感染的药物组合物，其包括至少一种具有通式（Z）的咪唑并[4,5-c]吡啶衍生物作为活性成分。本发明还涉及根据上述通式制备化合物的方法以及它们作为药物或用于治疗或预防病毒感染的用途。
• VIRAL INHIBITORS
  申请人：NEYTS Johan

  公开号：US20100004281A1

  公开（公告）日：2010-01-07

  The present invention relates to imidazo[4,5-c]pyridine compounds and pharmaceutical compositions for the treatment or prevention of viral infections, wherein the imidazo[4,5-c]pyridine compounds have the formula:

  本发明涉及咪唑并[4,5-c]吡啶化合物和制备其药学组合物用于治疗或预防病毒感染，其中咪唑并[4,5-c]吡啶化合物的化学式为：
• US7737162B2
  申请人：——

  公开号：US7737162B2

  公开（公告）日：2010-06-15
• US8779141B2
  申请人：——

  公开号：US8779141B2

  公开（公告）日：2014-07-15
• [EN] VIRAL INHIBITORS<br/>[FR] INHIBITEURS VIRAUX
  申请人：LEUVEN K U RES & DEV

  公开号：WO2004005286A2

  公开（公告）日：2004-01-15

  The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine derivative having the general formula (Z): (formula). The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections.