4-bromo-4'-ethoxy-2,3-difluoro-1,1-biphenyl | 470461-09-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromo-4'-ethoxy-2,3-difluoro-1,1-biphenyl
• 英文别名: 4-ethoxy-4'-bromo-2,3-difluoro-1,1'-biphenyl；4'-Bromo-4-ethoxy-2,3-difluoro-1,1'-biphenyl；1-(4-bromophenyl)-4-ethoxy-2,3-difluorobenzene
• CAS: 470461-09-7
• 化学式: C₁₄H₁₁BrF₂O
• 分子量: 313.142
• InChiKey: VFNYZNWPLITFPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险性防范说明：
  P264,P270,P301+P312,P330
• 危险性描述：
  H302,H315,H320,H335
• 储存条件：
  室温且干燥

反应信息

• 作为反应物：
  描述：

  4-bromo-4'-ethoxy-2,3-difluoro-1,1-biphenyl 在 正丁基锂 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 6.0h， 生成
  参考文献：
  名称：

  液晶化合物及包含它的液晶组合物

  摘要：

  本发明的一个示例性实施方案中提供一种在低旋转粘度下显示出高折射率各向异性及高电阻率特性的新液晶化合物。这种液晶化合物可以给各种液晶显示元件，特别是要求快速响应时间的VA、MVA、PVA、PS‑VA、PALC、FFS、PS‑FFS、IPS或PS‑IPS模式的液晶显示元件提供优化的液晶组合物。

  公开号：

  CN107001936B
• 作为产物：
  描述：

  对溴碘苯 、 2,3-二氟-4-乙氧基苯硼酸 在 trans-bis(triphenylphosphine)palladium dichloride 、 potassium carbonate 作用下， 以 水 、 甲苯 为溶剂， 反应 2.0h， 以94%的产率得到4-bromo-4'-ethoxy-2,3-difluoro-1,1-biphenyl
  参考文献：
  名称：

  液晶性化合物、液晶組成物および液晶表示素子

  摘要：

  【问题】本发明提供一种液晶性化合物，该化合物至少满足以下物性之一：对热和光的高稳定性、高透明点（或高上限温度）、液晶相的低下限温度、小粘度、适当的光学異方性、小的或负的大电介质異方性、适当的弹性常数、与其他液晶性化合物良好的相容性。本发明还提供一种含有该化合物的液晶组成物和一种包含该组成物的液晶显示器件。 【解决手段】本发明的解决手段是化合物等，如式（1）所示。其中，R1和R2是氢、烷基等；环A1、A2、A3和A4是1,4-环己烯、1,4-苯基等；Z1、Z2、Z3和Z4是单键、烷基等；a、b、c和d是0、1或2；连接基-CH(CH3)-CH(CH3)-的立体构型是treo。 【选图】无

  公开号：

  JP2020158394A

文献信息

• COMPOUND HAVING A FIVE-MEMBERED RING, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE
  申请人：MASUKAWA Tokifumi

  公开号：US20110309300A1

  公开（公告）日：2011-12-22

  The invention provides a liquid crystal compound that has an excellent compatibility with other liquid crystal compounds and also has at least one of characteristics such as a high stability to heat, light or the like, a suitable refractive index anisotropy (Δn), a low threshold voltage and a suitable dielectric anisotropy (Δ∈). A compound represented by formula (1). For example, R 1 is alkyl having 1 to 10 carbons, R 2 is halogen or alkenyl having 2 to 10 carbons; the ring A 1 , the ring A 2 and the ring A 3 are 1,4-cyclohexylene or 1,4-phenylene; Z 1 , Z 2 and Z 3 are a single bond or alkylene having 1 to 4 carbons; G is —CH 2 — or —O—; and m is 1, and n and p is 0 or 1.

  本发明提供了一种液晶化合物，其与其他液晶化合物具有良好的相容性，并具有高热稳定性、光稳定性或类似特性之一，适当的折射率各向异性（Δn）、低阈值电压和适当的介电各向异性（Δ∈）等特性。化合物由式（1）表示。例如，R1是具有1到10个碳的烷基，R2是具有2到10个碳的卤素或烯基；环A1、环A2和环A3是1,4-环己基或1,4-苯基；Z1、Z2和Z3是单键或具有1到4个碳的烷基；G是—CH2—或—O—；m为1，n和p为0或1。
• Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device
  申请人：JNC Corporation

  公开号：US08187494B2

  公开（公告）日：2012-05-29

  The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, and a suitable elastic constant K33, and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and a liquid crystal composition having stability to heat, light and so forth, a low viscosity, a large optical anisotropy, a suitable and negative dielectric anisotropy, and a suitable elastic constant K33, a low threshold voltage, a high maximum temperature (phase-transition temperature on a nematic phase-isotropic phase) of a nematic phase, and a low minimum temperature of the nematic phase. The liquid crystal compound which has a specific structure having fluorine at a lateral position and also having phenylene in which hydrogen on the benzene ring is replaced by fluorine, and a liquid crystal composition containing the compound are prepared.

  该发明提供了一种具有对热、光等具有稳定性、具有宽温度范围的向列相、具有较小粘度、适当的光学各向异性和适当的弹性常数K33，并且具有适当且负的介电各向异性以及与其他液晶化合物具有良好的相容性的液晶化合物，以及具有对热、光等具有稳定性、低粘度、较大的光学各向异性、适当且负的介电各向异性、适当的弹性常数K33、低阈值电压、高向列相的最高温度（向列相-等向相的相变温度）和低向列相的最低温度的液晶组合物。制备了具有特定结构的液晶化合物，其在侧位具有氟，并且苯环上的氢被氟取代，以及含有该化合物的液晶组合物。
• Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device
  申请人：JNC Corporation

  公开号：US08216489B2

  公开（公告）日：2012-07-10

  The invention provides a liquid crystal compound represented by the following formula having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a large optical anisotropy and a suitable elastic constant K33 (K33: bend elastic constant), and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and provides a liquid crystal composition including the compound, wherein R1 and R2 are hydrogen, alkyl or the like, ring A1 is trans-1,4-cyclohexylene, 1,4-phenylene or the like, L1 to L4 are hydrogen or fluorine, and at least three of them are fluorine; when the ring A1 is trans-1,4-cyclohexylene or the like, Z1 is a single bond, —(CH2)2— or the like, when ring A1 is 1,4-phenylene, Z1 is —(CH2)2— or the like.

  本发明提供了一种液晶化合物，其化学式如下，具有耐热、耐光等稳定性，具有宽广的向列相温度范围、小粘度、大光学各向异性及适当的弯曲弹性常数K33（K33：弯曲弹性常数），并且具有适当的负介电各向异性和与其他液晶化合物的良好相容性，以及提供了包括该化合物的液晶组合物。其中，R1和R2为氢、烷基或类似物，环A1为反式1,4-环己烯基、1,4-苯基或类似物，L1至L4为氢或氟，其中至少三个为氟；当环A1为反式1,4-环己烯基或类似物时，Z1为单键，—（CH2）2—或类似物，当环A1为1,4-苯基时，Z1为—（CH2）2—或类似物。
• FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Kobayashi Masahide

  公开号：US20100309402A1

  公开（公告）日：2010-12-09

  The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, and a suitable elastic constant K 33 , and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and a liquid crystal composition having stability to heat, light and so forth, a low viscosity, a large optical anisotropy, a suitable and negative dielectric anisotropy, and a suitable elastic constant K 33 , a low threshold voltage, a high maximum temperature (phase-transition temperature on a nematic phase-isotropic phase) of a nematic phase, and a low minimum temperature of the nematic phase. The liquid crystal compound which has a specific structure having fluorine at a lateral position and also having phenylene in which hydrogen on the benzene ring is replaced by fluorine, and a liquid crystal composition containing the compound are prepared.

  本发明提供了一种液晶化合物，具有耐热、耐光等稳定性，广泛的向列相温度范围，低粘度，适当的光学各向异性和适当的弹性常数K33，进一步具有适当且负的介电各向异性和与其他液晶化合物优异的相容性，以及一种液晶组合物，具有耐热、耐光等稳定性，低粘度，大的光学各向异性，适当且负的介电各向异性，适当的弹性常数K33，低阈值电压，向列相的高最大温度（向列相-等向相相变温度）和低向列相的最低温度。制备了一种具有侧位氟和苯环上氢被氟取代的苯基的特定结构的液晶化合物以及含有该化合物的液晶组合物。
• THREE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Kobayashi Masahide

  公开号：US20110037024A1

  公开（公告）日：2011-02-17

  The invention provides a liquid crystal compound represented by the following formula having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a large optical anisotropy and a suitable elastic constant K 33 (K 33 : bend elastic constant), and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and provides a liquid crystal composition including the compound, wherein R 1 and R 2 are hydrogen, alkyl or the like, ring A 1 is trans-1,4-cyclohexylene, 1,4-phenylene or the like, L 1 to L 4 are hydrogen or fluorine, and at least three of them are fluorine; when the ring A 1 is trans-1,4-cyclohexylene or the like, Z 1 is a single bond, —(CH 2 ) 2 — or the like, when ring A 1 is 1,4-phenylene, Z 1 is —(CH 2 ) 2 — or the like.

  该发明提供了一种液晶化合物，其由以下公式表示，具有耐热、耐光等稳定性，具有向列相的宽温度范围、小粘度、大光学各向异性和适当的弹性常数K33（K33：弯曲弹性常数），并且具有适当的负电介质各向异性和与其他液晶化合物良好的相容性，并提供了包括该化合物的液晶组合物，其中R1和R2是氢、烷基或类似物，环A1是反式-1,4-环己基、1,4-苯基或类似物，L1到L4是氢或氟，其中至少三个是氟；当环A1为反式-1,4-环己基或类似物时，Z1是单键，-(CH2)2-或类似物，当环A1为1,4-苯基时，Z1是-(CH2)2-或类似物。