Acetessigsaeuremethylester-dimethylhydrazon | 58706-80-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Acetessigsaeuremethylester-dimethylhydrazon
• 英文别名: Methylacetoacetat-N,N-dimethylhydrazon；Methyl 3-(dimethylhydrazinylidene)butanoate
• CAS: 58706-80-2
• 化学式: C₇H₁₄N₂O₂
• 分子量: 158.2
• InChiKey: XXSSOQHIYJHMEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Acetessigsaeuremethylester-dimethylhydrazon 、 氯羰基亚磺酰氯 在 N,N-二乙基苯胺 作用下， 以 甲苯 为溶剂， 反应 10.0h， 以82%的产率得到methyl <3-dimethylamino-4-methyl-2-oxo-2(3H)-thiazol-3-yl>carboxylate
  参考文献：
  名称：

  Regioselective Cyclocondensations of Chlorocarbonylsulfenyl Chloride with Hydrazones: Effective Synthesis of a Class of Sulfur and Nitrogen Containing Heterocycles with -COS- Linkage

  摘要：

  Regioselective cyclocondensations of several hydrazones with chlorocarbonylsulfenyl chloride afforded 1,3,4-(3H,6H)-thiadiazin-2-one derivatives and 3(2H)-(dimethylamino)thiazolones. The -COS- linkage was effectively incorporated into the S,N-containing heterocycles.

  DOI：

  10.3987/com-95-7242

文献信息

• Corey,E.J.; Enders,D., Chemische Berichte, 1978, vol. 111, p. 1362 - 1383
  作者：Corey,E.J.、Enders,D.

  DOI：——

  日期：——
• Regioselective Cyclocondensations of Chlorocarbonylsulfenyl Chloride with Hydrazones: Effective Synthesis of a Class of Sulfur and Nitrogen Containing Heterocycles with -COS- Linkage
  作者：Yoo Tanabe、Kei Mori、Yoshinori Nishii

  DOI：10.3987/com-95-7242

  日期：——

  Regioselective cyclocondensations of several hydrazones with chlorocarbonylsulfenyl chloride afforded 1,3,4-(3H,6H)-thiadiazin-2-one derivatives and 3(2H)-(dimethylamino)thiazolones. The -COS- linkage was effectively incorporated into the S,N-containing heterocycles.