[EN] COMPOUNDS AND METHOD OF USE THEREOF FOR TREATING BACTERIAL DISEASES<br/>[FR] COMPOSÉS ET LEUR PROCÉDÉ D'UTILISATION POUR TRAITER DES MALADIES BACTÉRIENNES
申请人:[en]PEKING UNIVERSITY
公开号:WO2023104017A1
公开(公告)日:2023-06-15
The present disclosure provides compounds that can inhibit the type III secretion system (TTSS) to decrease the pathogenesis of gram-negative bacteria. These compounds may have wide applications for treating bacteria diseases caused by gram-negative bacteria in a host species, including but not limited to, plants and animals. The present invention further relates to compositions that inhibit pathogenesis of gram-negative bacteria without killing the bacteria. Methods relating to preventing and/or treating infection of a host species by bacterial pathogens are also provided herein.