Docosahexaenoic acid ethyl ester | 84494-72-4

• 物质功能分类: 分析化学 - 食品安全 - 脂肪酸、脂肪酸甲酯
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Docosahexaenoic acid ethyl ester
• 英文别名: ethyl (4E,7E,10E,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenoate
• CAS: 84494-72-4
• 化学式: C₂₄H₃₆O₂
• 分子量: 356.5
• InChiKey: ITNKVODZACVXDS-YATCGRJWSA-N

物化性质

• 沸点：
  443.5±24.0 °C(Predicted)
• 密度：
  0.914±0.06 g/cm3(Predicted)
• 溶解度：
  溶于二甲基亚砜

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  26
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 安全说明：
  S24/25
• WGK Germany：
  3
• 海关编码：
  2916196000
• 危险性防范说明：
  P261,P280,P301+P312,P302+P352,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

制备方法与用途

生物活性

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate 是二十二碳六烯酸 (DHA) 的乙酯，是金枪鱼油和月桂醇反应中提出的醇化脂肪酸乙酯。

体外研究

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate（二十二碳六烯酸乙酯；E-DHA）通过使用固定化脂酶，高效地从金枪鱼油衍生的乙酯中选择性水解月桂醇获得。

文献信息

• Lewis acid-catalyzed polymerization of biological oils and resulting polymeric materials
  申请人：——

  公开号：US20020095007A1

  公开（公告）日：2002-07-18

  Biological oils, conjugated biological oils, and metathesized or cometathesized biological oils are polymerized or co-polymerized with comonomers, which include styrene and divinylbenzene, norbornadiene and dicyclopentadiene, using a BF 3 .OEt 2 initiator to provide plastics from renewable resources. The compositions are thermosetting polymers having damping and shape memory characteristics. These compositions can become industrial products of an unlimited variety.

  生物油、共轭生物油、以及通过交换反应或者共交换反应制备的生物油与诸如苯乙烯和二乙烯基苯、去氢环戊二烯和二环戊二烯等共聚单体聚合或共聚合，使用BF3.OEt2引发剂，以提供可再生资源的塑料。这些组合物是热固性聚合物，具有阻尼和形状记忆特性。这些组合物可以成为各种工业产品。
• ANTIVIRAL AND IMMUNOSTIMULATING MARINE FISH OIL COMPOSITION
  申请人：SINNEX MÜSZAKI FEJLESZTÖ ÉS TANÁCSADÓ KFT

  公开号：EP1830861B1

  公开（公告）日：2009-04-22
• Solid phase extraction method for obtaining high-purity unsaturated compounds or derivatives of said compounds
  申请人：——

  公开号：US20040162437A1

  公开（公告）日：2004-08-19

  The invention relates to a novel extraction method for obtaining at least one unsaturated, optionally derivatised compound, from mixtures of said compounds with other less saturated constituents, e.g. for obtaining polyunsaturated fatty acids or the derivatives thereof from mixtures with saturated and/or less unsaturated, optionally derivatised fatty acids, by means of selective complexation with a cation exchanger which is partially or fully charged with silver ions, and subsequent decomplexation.
• Novel Antiviral and Immune Stimulant Pharmaceutical Composition
  申请人：Szilbereky Jeno

  公开号：US20080131519A1

  公开（公告）日：2008-06-05

  The invention relates to a novel antiviral and immune-simulating pharmaceutical composition, containing as active ingredient 20-85 mass % of a ω-3-polyunsaturated fatty acid ester, in fish oil concentrate containing 20-70 mass % of a 5,8,11,14,17-eicosapentaenic acid ester and a 4,7,10,13,16,19-docosahexaenic acid ester, further 1-lysine of a salt thereof, optionally a zinc salt, selenium or a selenium compound, as well as additives and carrier ingredients.
• Complex Human Gut Microbiome Cultured In An Anaerobic Human Gut-On-A-Chip
  申请人：President and Fellows of Harvard College

  公开号：US20210079356A1

  公开（公告）日：2021-03-18

  A microfluidic device is directed to sustaining a complex microbial community in direct and indirect contact with living human intestinal cells in vitro. The device includes a first microchannel having cultured cells of a human intestinal epithelium and microbiota, the first microchannel further having a first level of oxygen. The device further includes a second microchannel having cultured cells of a vascular endothelium, the second microchannel further having a second level of oxygen. The device also includes a membrane located at an interface region between the first microchannel and the second microchannel, the membrane being composed of an oxygen-permeable material or further having pores via which oxygen flows between the first microchannel and the second microchannel to form a physiologically-relevant oxygen gradient.