申请人:Otsuka Kagaku Kabushiki Kaisha
公开号:EP0214600A2
公开(公告)日:1987-03-18
A cephalosporin compound substituted by imidazolium ring in 3-position of cephem having the following formula (I), and pharmaceutically acceptable salt thereof,
wherein R1 is an organic residue known in β-lactam antibiotics, R2 is hydrogen atom or methoxy, n is 0 or 1, A is a nitrogen-containing group constituting imidazolium ring, is useful as an agent for preventing and treating bacterial infections.
一种在头孢菌素的 3 位被咪唑环取代的头孢菌素化合物,具有下式(I)及其药学上可接受的盐、
其中 R1 是β-内酰胺类抗生素中已知的有机残基,R2 是氢原子或甲氧基,n 是 0 或 1,A 是构成咪唑环的含氮基团,可作为预防和治疗细菌感染的药物。