4-Oxo-4-(2,2,2-trifluoroethoxy)but-2-enoic acid | 752201-52-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Oxo-4-(2,2,2-trifluoroethoxy)but-2-enoic acid
• CAS: 752201-52-8
• 化学式: C₆H₅F₃O₄
• 分子量: 198.099
• InChiKey: DMOCYKURYFDHHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  4-Oxo-4-(2,2,2-trifluoroethoxy)but-2-enoic acid 在 草酰氯 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 1.0h， 生成 C₆H₄ClF₃O₃
  参考文献：
  名称：

  [4 + 2] Cycloaddition Reactions Catalyzed by a Chiral Oxazaborolidinium Cation. Reaction Rates and Diastereo-, Regio-, and Enantioselectivity Depend on Whether Both Bonds Are Formed Simultaneously

  摘要：

  The reaction rates and products in enantioselective Diels-Alder reactions with a range of dienophiles correlate with the expected degree of concertedness of bond formation in the transition state.

  DOI：

  10.1021/ol100032u
• 作为产物：
  描述：

  马来酸酐 、 2,2,2-三氟乙醇 在 N,N-二异丙基乙胺 、 盐酸 作用下， 以 水 为溶剂， 以75%的产率得到4-Oxo-4-(2,2,2-trifluoroethoxy)but-2-enoic acid
  参考文献：
  名称：

  [4 + 2] Cycloaddition Reactions Catalyzed by a Chiral Oxazaborolidinium Cation. Reaction Rates and Diastereo-, Regio-, and Enantioselectivity Depend on Whether Both Bonds Are Formed Simultaneously

  摘要：

  The reaction rates and products in enantioselective Diels-Alder reactions with a range of dienophiles correlate with the expected degree of concertedness of bond formation in the transition state.

  DOI：

  10.1021/ol100032u

文献信息

• Use of adsorbent polymer particles in DNA separation
  申请人：——

  公开号：US20030162853A1

  公开（公告）日：2003-08-28

  The invention is directed to fluorinated particles having adsorbent properties for superior performance as the stationary phase for use in chromatographic separations. In particular, the fluorinated surface of such particles of the invention presents unusual and unexpected polarity that is beneficial in performing chromatographic separations such as that used for DNA.

  本发明涉及具有吸附性能的氟化颗粒，用作色谱分离中的固定相，以实现卓越的性能。特别地，本发明中这些颗粒的氟化表面呈现出不寻常和意外的极性，在进行色谱分离（例如用于DNA的分离）时具有益处。
• Latently-curable organosilicone release coating composition
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0140530A1

  公开（公告）日：1985-05-08

  A latently-curable, organosilicone composition comprises a metal catalyzed organosilicone composition capable of undergoing hydrosilation and, as hydrosilation inhibitor, an organic monohydrogen derivative of an unsaturated aliphatic 1,4-dicarboxylic acid, i.e., maleic acid or acetylene dicarboxylic acid. The organic monohydrogen derivatives of use in this invention effectively inhibit catalyzed hydrosilation reactions at low or room temperature while allowing efficient hydrosilation reaction rates to occur at elevated temperatures. These monohydrogen derivatives perform their inhibitive function effectively at low concentration. The latently curable composition may be coated on a substrate to provide a release surface for an adjacent adhesive layer.

  一种潜伏固化的有机硅组合物包括一种可进行水合反应的金属催化有机硅组合物，以及作为水合反应抑制剂的不饱和脂肪族 1,4-二羧酸（即马来酸或乙炔二羧酸）的有机单氢衍生物。本发明中使用的有机单氢衍生物可在低温或室温下有效抑制催化的加氢反应，同时允许在高温下发生高效的加氢反应。这些单氢衍生物在低浓度下就能有效发挥其抑制功能。潜伏固化组合物可涂在基材上，为相邻的粘合剂层提供脱模表面。
• New electrode materials derived from polyquinonic ionic compounds and their use in electrochemical generators
  申请人：——

  公开号：US20030118877A1

  公开（公告）日：2003-06-26

  The present invention is concerned with novel compounds derived from polyquinonic ionic compounds and their use in electrochemical generators.

  本发明涉及由多醌离子化合物衍生的新型化合物及其在电化学发生器中的应用。
• PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES
  申请人：Prometic Biosciences Inc.

  公开号：EP1194479B1

  公开（公告）日：2004-02-18
• ADHESION PROMOTING ADDITIVE
  申请人：AVERY DENNISON CORPORATION

  公开号：EP2024440A2

  公开（公告）日：2009-02-18