diethyl 2-furyl(methyl)malonate | 197096-76-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: diethyl 2-furyl(methyl)malonate
• 英文别名: Diethyl 2-(furan-2-yl)-2-methylmalonate；diethyl 2-(furan-2-yl)-2-methylpropanedioate
• CAS: 197096-76-7
• 化学式: C₁₂H₁₆O₅
• 分子量: 240.256
• InChiKey: WDSAGYBNSJVGEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  65.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  diethyl 2-furyl(methyl)malonate 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 以58 %的产率得到2-(2-furyl)-2-methylpropane-1,3-diol
  参考文献：
  名称：

  US2022/380496

  摘要：

  公开号：
• 作为产物：
  描述：

  呋喃 、 Diethyl methyl malonate 以72 %的产率得到diethyl 2-furyl(methyl)malonate
  参考文献：
  名称：

  US2022/380496

  摘要：

  公开号：

文献信息

• Malonylation/Decarbalkoxylation of Furan Derivatives as Key Steps for the Preparation of Nonactic Acid Derivatives. Part I [1]
  作者：Jean-Mary Simone、François Loiseau、David Carcache、Pavel Bobal、Julie Jeanneret-Gris、Reinhard Neier

  DOI：10.1007/s00706-006-0579-9

  日期：2007.2

  A malonylation/decarbalkoxylation sequence from 2-substituted furans was investigated in view of developing a scalable synthesis of hydrophobic nonactic acid analogues.

  考虑到开发疏水性非乳酸类似物的可扩展合成，研究了来自2-取代的呋喃的丙二酰化/脱羧烷氧基化序列。
• 2,5-DISUBSTITUTED FURANS BY OXIDATION OF β-DICARBONYL COMPOUNDS IN THE PRESENCE OF FURAN
  作者：Attilio Citterio、Maffezzoni Tino、Maronati Antonietta、Roberto Sebastiano

  DOI：10.1080/00304949709355239

  日期：1997.10
• ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION
  申请人：Borealis AG

  公开号：US20220380496A1

  公开（公告）日：2022-12-01

  The present invention relates to optionally substituted 1,3-dimethoxypropanes and 3-methoxypropylamines, and more particularly to their use as internal donors in Ziegler-Natta catalysts to obtain polymers with desirable properties. The present disclosure further concerns Ziegler-Natta catalyst components comprising said optionally substituted 1,3-dimethoxypropanes and 3-methoxypropylamines, and Ziegler-Natta catalysts for olefin polymerization comprising said Ziegler-Natta catalyst components, as well as a method for preparing the same and their use in providing polyolefins.
• [EN] ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION<br/>[FR] CATALYSEURS ZIEGLER-NATTA POUR LA POLYMÉRISATION D'OLÉFINES
  申请人：BOREALIS AG

  公开号：WO2021064078A1

  公开（公告）日：2021-04-08

  The present invention relates to optionally substituted 1,3-dimethoxypropanes and 3- methoxypropylamines, and more particularly to their use as internal donors in Ziegler-Natta catalysts to obtain polymers with desirable properties. The present disclosure further concerns Ziegler-Natta catalyst components comprising said optionally substituted 1,3- dimethoxypropanes and 3-methoxypropylamines, and Ziegler-Natta catalysts for olefin polymerization comprising said Ziegler-Natta catalyst components, as well as a method for preparing the same and their use in providing polyolefins.
• US2022/380496
  申请人：——

  公开号：——

  公开（公告）日：——