(E)-methyl2-allyl-3-bromooct-2-enoate | 1446623-66-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-methyl2-allyl-3-bromooct-2-enoate
• 英文别名: methyl (E)-3-bromo-2-prop-2-enyloct-2-enoate
• CAS: 1446623-66-0
• 化学式: C₁₂H₁₉BrO₂
• 分子量: 275.186
• InChiKey: SDKVKVUEVCEVHN-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  辛酸甲酯 、 烯丙醇 在 copper(ll) bromide 、 palladium dichloride 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 以90%的产率得到(E)-methyl2-allyl-3-bromooct-2-enoate
  参考文献：
  名称：

  Synthesis of 1-bromo-1,4-dienes via palladium-catalyzed bromoallylation of alkynes

  摘要：

  An efficient procedure for the synthesis of a series of 1-bromo-1,4-dienes by a simple Pd-catalyzed intermolecular tandem reaction of alkynes, CuBr2, and allylic alcohol has been developed. The reaction proceeds smoothly under mild condition to give the corresponding products in good to excellent yields. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.084

文献信息

• Synthesis of 1-bromo-1,4-dienes via palladium-catalyzed bromoallylation of alkynes
  作者：Yanmei Wen、Huanfeng Jiang

  DOI：10.1016/j.tetlet.2013.05.084

  日期：2013.7

  An efficient procedure for the synthesis of a series of 1-bromo-1,4-dienes by a simple Pd-catalyzed intermolecular tandem reaction of alkynes, CuBr2, and allylic alcohol has been developed. The reaction proceeds smoothly under mild condition to give the corresponding products in good to excellent yields. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.