Ag[P(O)(OEt)2] | 89620-99-5

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 英文名称: Ag[P(O)(OEt)2]
• 英文别名: silver diethyl phosphonate；phosphonic acid diethyl ester; silver salt；Phosphonsaeure-diaethylester; Silbersalz；Silver;diethyl phosphite
• CAS: 89620-99-5
• 化学式: Ag*C₄H₁₀O₃P
• 分子量: 244.964
• InChiKey: ICOJCNOUKOCEKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.64
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  41.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ag[P(O)(OEt)2] 生成 亚磷酸三乙酯
  参考文献：
  名称：

  Avulsion injuries of vertebral endplates

  摘要：

  Bone changes resulting from avulsions involving vertebral endplates have had little, if any, systematic attention in palaeopathological literature. To gain insight into their occurrence and into their variety, two archaeological skeletal collections covering the period AD 1455-1824 were examined. Additional skeletal material was used to illustrate typical examples. A quarter of the 44 adults who had adequate numbers of vertebrae at all spinal levels showed minor to major vertebral endplate changes as a result of avulsion injuries. The male/female ratio was 7:4. The ration of individuals with injuries contracted during their youth and during their adulthood was 3:8 (n=11). Approximately half of the affected individuals showed such changes in multiple vertebrae. In about one third of the cases, concomitant vertebral fractures, which did not involve the endplates, were recorded. Since the existing classifications of endplate changes from avulsion injuries were developed on the basis of clinical diagnoses made by means of X-ray or by autopsy, an adapted and extended outline for palaeopathological use is proposed. A series of differential diagnoses is discussed. Although, in general, the poor preservation of archaeological spines hampers epidemiology, the diagnosis of spinal avulsion injuries offers interesting information at the individual level. Copyright (c) 2000 John Wiley & Sons, Ltd.

  DOI：

  10.1002/(sici)1099-1212(200003/04)10:2<142::aid-oa519>3.0.co;2-l
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 silver nitrate 作用下， 生成 Ag[P(O)(OEt)2]
  参考文献：
  名称：

  Homonymous hemianopia in a pug with necrotising meningoencephalitis

  摘要：

  A 24‐month‐old female pug, which had previously been treated for visual hemifield loss, was referred with generalised seizures and other neurological disorders. A diagnosis of necrotising meningoencephalitis was suggested from the clinical signs together with the results of computed tomography and cerebrospinal fluid examination. This was confirmed seven months later by histological examination of the brain following euthanasia. Typical histopathological lesions of the disease were found in various areas of both cerebral hemispheres, including the visual striated cortex of the right cerebrum.

  DOI：

  10.1111/j.1748-5827.2000.tb03186.x

文献信息

• External oxidant-free cross-coupling: electrochemically induced aromatic C–H phosphonation of azoles with dialkyl-<i>H</i>-phosphonates under silver catalysis
  作者：E. O. Yurko、T. V. Gryaznova、K. V. Kholin、V. V. Khrizanforova、Y. H. Budnikova

  DOI：10.1039/c7dt03650g

  日期：——

  phosphorus precursors and intermediates using cyclic voltammetry, ESR, and NMR spectroscopy were investigated, and a radical process mechanism was proposed. It has been found that AgP(O)(OEt)2 is oxidized earlier than other components of the reaction mixture with the elimination of a radical. The ESR spectrum of this radical's adduct was obtained in the presence of the radical trap PBN. Ag2+ is out of

  吡咯衍生物（苯并-1,3-唑类，3-甲基吲哚，4-甲基-2- acetylthiazole）的磷酸化，通过使用二烷基甲方便外部无氧化剂的方法ħ -phosphonates通过他们的混合物的下电化学温和催化氧化建议在银盐或氧化物（1％）存在的条件下（室温，常压）。该方法使我们能够以良好的收率（高达75％）获得所需的唑二烷基膦酸酯。研究了使用循环伏安法，ESR和NMR光谱分析银和磷的前体和中间体的转化过程，并提出了自由基处理机理。已发现AgP（O）（OEt）2在消除自由基的情况下，其比反应混合物的其他组分更早地被氧化。该自由基加合物的ESR光谱是在自由基陷阱PBN存在下获得的。Ag 2+已脱离催化循环。
• Nickel-Catalyzed Decarboxylative C–P Cross-Coupling of Alkenyl Acids with P(O)H Compounds
  作者：Yile Wu、Liu Leo Liu、Kaili Yan、Pengxiang Xu、Yuxing Gao、Yufen Zhao

  DOI：10.1021/jo501321m

  日期：2014.9.5

  The first nickel-catalyzed decarboxylative C–P coupling of a wide range of alkenyl acids with various P(O)H compounds, especially for H-phosphonates, has been developed, affording a versatile and efficient tool for the preparation of valuable (E)-1-alkenylphosphonates, (E)-1-alkenylphosphinate oxides, and (E)-1-alkenylphosphine oxides with high stereoselectivity and broad substrate applicability. DFT

  已开发出首个镍催化的各种烯基酸与各种P（O）H化合物（特别是对于H膦酸酯）的脱羧C-P偶联，为制备有价值的（E）提供了一种通用而有效的工具-1- alkenylphosphonates，（ë）-1- alkenylphosphinate氧化物，和（ë）高立体选择性和广泛的底物的适用性-1- alkenylphosphine氧化物。DFT计算表明，由于亲核性强和尺寸大，在还原消除步骤中膦配体比氮配体表现出更好的催化性能。
• Arylpalladium Phosphonate Complexes as Reactive Intermediates in Phosphorus−Carbon Bond Forming Reactions
  作者：Mark C. Kohler、Thomas V. Grimes、Xiaoping Wang、Thomas R. Cundari、Robert A. Stockland

  DOI：10.1021/om800906m

  日期：2009.2.23

  reactions, palladium complexes containing electron-donating substituents on the aromatic fragment exhibited faster rates of reductive elimination. Large bite angle diphosphine ligands induced rapid rates of elimination, while bipyridine and small bite angle diphosphine ligands resulted in much slower rates of elimination. An investigation of the effect of typical impurities on the elimination reaction

  由离散的过渡金属络合物形成的磷-碳键已通过合成，光谱，晶体学和计算方法的组合进行了研究。（二膦）Pd（芳基）（P（O）（OEt）2类型的反应性中间体）已经被制备，表征和研究为金属介导的偶联反应中的可能中间体。几种反应性中间体在晶体学上进行了表征，并对固态结构进行了讨论。与其他碳-杂原子键形成反应相反，在芳族片段上包含给电子取代基的钯配合物表现出更快的还原消除速率。大咬合角二膦配体诱导快速消除，而联吡啶和小咬合角二膦配体导致缓慢得多的消除。研究了典型杂质对消除反应的影响。虽然过量的二膦，吡啶和乙腈对观察到的速率影响很小，加水减慢了磷碳键的形成反应。在光谱和晶体学上观察到水与配合物的配位。计算研究被用来探测通过Pd催化形成Pc键的反应途径。
• Steric and Electronic Effects on Arylphosphonate Elimination from Organopalladium Complexes
  作者：Mark C. Kohler、Robert A. Stockland,、Nigam P. Rath

  DOI：10.1021/om060662i

  日期：2006.11.1

  To study the effects of electronic and steric manipulation of metal-bound aryl fragments on arylphosphonate formation, model organopalladium complexes have been prepared and investigated. While no phosphorus−carbon bond formation was observed at 25 °C, all of the arylpalladium phosphonates underwent clean reductive elimination in C6D6 solutions at elevated temperatures. The incorporation of electron-donating

  为了研究金属结合的芳基片段的电子和空间操纵对芳基膦酸酯形成的影响，已经制备并研究了模型有机钯配合物。尽管在25°C时未观察到磷碳键的形成，但所有芳基钯膦酸酯均在C 6 D 6中进行了干净的还原消除。高温下的溶液。给电子基团结合到金属结合的芳基片段中加速了消除过程，而含有带有吸电子或邻位取代基的芳基的钯配合物则显示出较慢的消除速率。尽管芳基膦酸酯形成的速率取决于与金属结合的芳基片段的性质，但它对膦酸酯部分的身份相当不敏感。这些结果证明了在P（O）-C键形成反应中消除物种的电子和空间组成发生细微变化的结果。
• The salts of organic phosphorus acids—II(1) The infra-red spectra of salts of di-alkyl phosphites
  作者：T.D. Smith

  DOI：10.1016/0022-1902(60)80015-2

  日期：1960.9

  The infra-red spectra of the sodium, magnesium, silver and mercury salts of a number of di-alkyl phosphites have been recorded and correlated with structural changes imposed upon the di-alkyl phosphite anion by the metal ion present.

  已经记录了许多亚磷酸二烷基酯的钠，镁，银和汞盐的红外光谱，并与存在的金属离子对亚磷酸二烷基酯施加的结构变化相关。