[EN] PYRAZOLYL INDOLYL DERIVATIVES AS PPAR ACTIVATORS<br/>[FR] DERIVES DE PYRAZOLYL-INDOLYLE UTILISES COMME ACTIVATEURS DE PPAR
申请人:HOFFMANN LA ROCHE
公开号:WO2005085235A1
公开(公告)日:2005-09-15
This invention is concerned with compounds of the formula (I), wherein one of R6, R7 and R8 is (II), and R1 to R15 and n are as defined in the description, and all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
Indolyl derivatives
申请人:Ackermann Jean
公开号:US20050203160A1
公开(公告)日:2005-09-15
This invention relates to compounds of the formula I:
wherein one of R
6
, R
7
and R
8
is
and R
1
to R
15
and n are as defined in the description, and all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR δ and/or PPARα agonists.