acetic acid pent-2-enyl ester | 10500-10-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: acetic acid pent-2-enyl ester
• 英文别名: Essigsaeure-pent-2-enylester；Penten-(2)-ylacetat；1-Acetoxy-penten-2；2-Penten-1-yl acetate；pent-2-enyl acetate
• CAS: 10500-10-4
• 化学式: C₇H₁₂O₂
• 分子量: 128.171
• InChiKey: WGGJTPQHVFOGPN-UHFFFAOYSA-N

物化性质

• 沸点：
  149-151 °C
• 密度：
  0.9019 g/cm3(Temp: 22 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  acetic acid pent-2-enyl ester 、 alkaline earth salt of/the/ methylsulfuric acid 生成 反-2-戊烯-1-醇
  参考文献：
  名称：

  Meisenheimer; Link, Justus Liebigs Annalen der Chemie, 1930, vol. 479, p. 226,261,262

  摘要：

  DOI：
• 作为产物：
  描述：

  1-戊烯-3-醇 在 溶剂黄146 、 三氯化磷 作用下， 生成 acetic acid pent-2-enyl ester
  参考文献：
  名称：

  Prevost, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1928, vol. 187, p. 1053

  摘要：

  DOI：

文献信息

• Dual Ni/Organophotoredox Catalyzed Allylative Ring Opening Reaction of Oxabenzonorbornadienes and Analogs
  作者：Abdoul G. Diallo、Déborah Paris、Djiby Faye、Sylvain Gaillard、Mark Lautens、Jean-Luc Renaud

  DOI：10.1021/acscatal.2c00512

  日期：2022.3.18

  A general approach for the allylation of oxa- and azabenzonorbornadienes is reported by merging organophotoredox and nickel catalysis. This methodology allowed the diastereoselective allylation of various heterocyclic alkene derivatives with a broader range of allylic acetate compounds compared to previously published procedures. Moreover, no air-sensitive organometallic species and no metal reductants

  通过合并有机光氧化还原和镍催化，报道了一种用于氧杂和氮杂苯并降冰片二烯烯丙基化的一般方法。与先前公布的程序相比，这种方法允许各种杂环烯烃衍生物与更广泛的烯丙基乙酸酯化合物进行非对映选择性烯丙基化。此外，开环不需要对空气敏感的有机金属物质和金属还原剂（例如锌或锰）。机理研究表明，开环是通过碳金属化过程进行的。
• Bouis, Annales de Chimie (Cachan, France), 1928, vol. <10>9, p. 420
  作者：Bouis

  DOI：——

  日期：——
• Baudrenghien, Bulletin des Societes Chimiques Belges, 1923, vol. 32, p. 338
  作者：Baudrenghien

  DOI：——

  日期：——
• Membrane currents in cultured human intestinal smooth muscle cells
  作者：A. V. Zholos、C. J. Fenech、S. A. Prestwich、T. B. Bolton

  DOI：10.1111/j.1469-7793.2000.00521.x

  日期：2000.11

  1. Using whole-cell patch-clamp recording techniques, we have examined voltage-gated ion currents in a cultured human intestinal smooth muscle cell line (HISM). Experiments were performed at room temperature on cells after passages 16 and 17.2. Two major components of the whole-cell current were a tetraethylammonium-sensitive (IC50 = 9 mM), iberiotoxin-resistant, delayed rectifier K+ current and a Na+ current inhibited by tetrodotoxin (IC50 approximate to 100 nM). No measurable inward current via voltage-gated Ca2+ channels could be detected in these cells even with 10 mM Ca2+ or Ba2+ in the external solution. No current attributable to calcium-activated K+ channels was found and no cationic current in response to muscarinic receptor activation was present.3. In divalent cation-free external solution two additional currents were activated: an inwardly rectifying hyperpolarization-activated current, I-HA, and a depolarization-activated current, I-DA.4. I-HA and I-DA could be carried by several monovalent cations; the sizes of currents in descending order were: K+ > Cs+ > Na+ for I-HA and Na+ > K+ much greater than Cs+ for I-DA. I-HA was activated and deactivated instantaneously and showed no inactivation whereas I-DA was activated, inactivated and deactivated within tens of milliseconds. These currents were inhibited by external calcium with an IC50 of 0.3 muM for I-DA and an IC50 of 20 muM for I-HA5. Cyclopiazonic acid (CPA) induced an outward, but not an inward current. SK&F 96365, a blocker of store-operated Ca2+ channels, suppressed I-DA With a. half-maximal inhibitory concentration of 9 muM but was ineffective in inhibiting I-HA at concentrations up to 100 muM. Gd3+ and La3+ strongly suppressed I-DA at 1 and 10 muM, respectively and were less effective in blocking I-HA (complete inhibition required a concentration of 100 muM for both). Carbachol at 10-100 muM evoked about a S-fold increase in I-HA amplitude and completely abolished I-DA.6. We conclude that I-HA and I-DA, are Ca2+-blockable cationic currents with different ion selectivity profiles that are carried by different channels. I-DA shows novel voltage-dependent properties for a cationic current.
• Allylic oxidation of olefins by mercuric acetate
  作者：Zvi Rappoport、S. Winstein、W. G. Young

  DOI：10.1021/ja00762a025

  日期：1972.4