1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine | 1445304-72-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine
• CAS: 1445304-72-2
• 化学式: C₁₅H₈Br₂N₂O₂
• 分子量: 408.049
• InChiKey: DEWIOQKGZPLDQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine 、 thallium (I) ethoxide 以 四氢呋喃 为溶剂， 反应 24.0h， 以69.5%的产率得到
  参考文献：
  名称：

  Synthesis and Characterization of Some Thallium Cyclopentadienide Fused Ring Pyridazines

  摘要：

  Thallium cyclopentadiene (Cp) salts are important precursors for the synthesis of a variety of compounds having materials and commercial applications. The synthesis of 5,6-fused ring thallium Cp pyridazines 2a-d from previously reported 5,6-fused ring pyridazines is described herein. This route was quite general, and features an efficient and convenient two-step synthesis of a series of TlCp salts in a THF solution of thallium ethoxide. Full characterization of newly formed TlCp salts 3a-d are reported.

  DOI：

  10.1080/00397911.2012.698356
• 作为产物：
  描述：

  在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以25.6%的产率得到1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine
  参考文献：
  名称：

  Synthesis and Characterization of Some Thallium Cyclopentadienide Fused Ring Pyridazines

  摘要：

  Thallium cyclopentadiene (Cp) salts are important precursors for the synthesis of a variety of compounds having materials and commercial applications. The synthesis of 5,6-fused ring thallium Cp pyridazines 2a-d from previously reported 5,6-fused ring pyridazines is described herein. This route was quite general, and features an efficient and convenient two-step synthesis of a series of TlCp salts in a THF solution of thallium ethoxide. Full characterization of newly formed TlCp salts 3a-d are reported.

  DOI：

  10.1080/00397911.2012.698356