1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine | 1445304-72-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine
• CAS: 1445304-72-2
• 化学式: C₁₅H₈Br₂N₂O₂
• 分子量: 408.049
• InChiKey: DEWIOQKGZPLDQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine 、 thallium (I) ethoxide 以 四氢呋喃 为溶剂， 反应 24.0h， 以69.5%的产率得到
  参考文献：
  名称：

  Synthesis and Characterization of Some Thallium Cyclopentadienide Fused Ring Pyridazines

  摘要：

  Thallium cyclopentadiene (Cp) salts are important precursors for the synthesis of a variety of compounds having materials and commercial applications. The synthesis of 5,6-fused ring thallium Cp pyridazines 2a-d from previously reported 5,6-fused ring pyridazines is described herein. This route was quite general, and features an efficient and convenient two-step synthesis of a series of TlCp salts in a THF solution of thallium ethoxide. Full characterization of newly formed TlCp salts 3a-d are reported.

  DOI：

  10.1080/00397911.2012.698356
• 作为产物：
  描述：

  在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以25.6%的产率得到1,4-bis(5-bromofuran-2-yl)-2H-cyclopenta[d]pyridazine
  参考文献：
  名称：

  Synthesis and Characterization of Some Thallium Cyclopentadienide Fused Ring Pyridazines

  摘要：

  Thallium cyclopentadiene (Cp) salts are important precursors for the synthesis of a variety of compounds having materials and commercial applications. The synthesis of 5,6-fused ring thallium Cp pyridazines 2a-d from previously reported 5,6-fused ring pyridazines is described herein. This route was quite general, and features an efficient and convenient two-step synthesis of a series of TlCp salts in a THF solution of thallium ethoxide. Full characterization of newly formed TlCp salts 3a-d are reported.

  DOI：

  10.1080/00397911.2012.698356

文献信息

• Synthesis and Characterization of Some Thallium Cyclopentadienide Fused Ring Pyridazines
  作者：Jason O. E. Young、Chad A. Snyder、Nathan C. Tice、Seth L. Sloan、Adam C. Smith、Sana A. Shah、Levi A. Dopierala、Michael S. Crocker、Yuto Kobayashi、Michael G. Mazzotta

  DOI：10.1080/00397911.2012.698356

  日期：2013.9.17

  Thallium cyclopentadiene (Cp) salts are important precursors for the synthesis of a variety of compounds having materials and commercial applications. The synthesis of 5,6-fused ring thallium Cp pyridazines 2a-d from previously reported 5,6-fused ring pyridazines is described herein. This route was quite general, and features an efficient and convenient two-step synthesis of a series of TlCp salts in a THF solution of thallium ethoxide. Full characterization of newly formed TlCp salts 3a-d are reported.