1,3-bis(2-morpholinoethyl)urea | 92168-90-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 1,3-bis(2-morpholinoethyl)urea
• 英文别名: 1,3-Bis-<2-morpholino-ethyl>-harnstoff；1,3-bis-(2-morpholin-4-yl-ethyl)-urea；N,N'-bis-(2-morpholino-ethyl)-urea；N,N'-Bis-(2-morpholino-aethyl)-harnstoff；N,Na(2)-Bis[2-(4-morpholinyl)ethyl]urea；1,3-bis(2-morpholin-4-ylethyl)urea
• CAS: 92168-90-6
• 化学式: C₁₃H₂₆N₄O₃
• 分子量: 286.374
• InChiKey: BXKZTHFWTIEYSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  66.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N-(2-氨基乙基)吗啉 、 alkaline earth salt of/the/ methylsulfuric acid 在 甲醇 、 sulfur 作用下， 生成 1,3-bis(2-morpholinoethyl)urea
  参考文献：
  名称：

  Electronic on-and-off control

  摘要：

  公开号：

  US02858430A1

文献信息

• Ruthenium-Catalyzed Urea Synthesis by N–H Activation of Amines
  作者：Varadhan Krishnakumar、Basujit Chatterjee、Chidambaram Gunanathan

  DOI：10.1021/acs.inorgchem.7b00962

  日期：2017.6.19

  observed in situ, which resulted in the formation of CO and dimethylamine. The scope of this new mode of bond activation is extended to the synthesis of urea derivatives from amines using DMF as a carbon monoxide (CO) surrogate. This catalytic protocol allows the synthesis of simple and functionalized urea derivatives with liberation of hydrogen, devoid of any stoichiometric activating reagents, and avoids

  证明了通过“胺-酰胺”金属-配体配合作用的钌夹钳络合物活化了胺的N-H键。N，N的催化甲酰C–H活化在原位观察到-二甲基甲酰胺（DMF），其导致CO和二甲基胺的形成。这种新的键激活模式的范围扩展到了使用DMF作为一氧化碳（CO）替代物由胺合成脲衍生物的范围。该催化方案允许在不释放任何化学计量活化剂的情况下释放氢而合成简单且功能化的尿素衍生物，并且避免直接使用致命性CO。分离出甲酰胺中间体。连续添加不同的胺可提供不对称的脲化合物。提议通过胺的N–H活化，随后DMF中的CO插入和二氢的释放进行反应。
• Reactive catalyst compositions for improving water blown polyurethane foam performance
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0877042A1

  公开（公告）日：1998-11-11

  The present invention provides a reactive catalyst composition for making a water blown flexible polyurethane foam. The catalyst composition comprises a tertiary amino alkyl urea and/or bis(tertiary amino alkyl) urea in combination with either a gelling catalyst or blowing catalyst. The use of such catalyst composition improves the physical properties of the polyurethane foam.

  本发明提供了一种用于制造水发泡软质聚氨酯泡沫的活性催化剂组合物。该催化剂组合物由叔氨基烷基脲和/或双叔氨基烷基脲与胶凝催化剂或发泡催化剂组合而成。使用这种催化剂组合物可以改善聚氨酯泡沫塑料的物理性能。
• Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP1443065A1

  公开（公告）日：2004-08-04

  The present invention relates to an improvement in flexible, semi-flexible and rigid foams formed by the catalytic reaction of an aromatic polyisocyanate, a polyol and a blowing agent and a process for preparing such polyisocyanate. The improvement resides in using an effective amount of a bismuth carboxylate or bismuth sulfonate having less than 34% free acid as the catalyst.

  本发明涉及芳香族多异氰酸酯、多元醇和发泡剂催化反应形成的软质、半软质和硬质泡沫的改进，以及制备这种多异氰酸酯的工艺。改进之处在于使用了有效量的游离酸小于 34% 的羧酸铋或磺酸铋作为催化剂。
• Fast demold/extended cream time polyurethane formulations
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP1600465A2

  公开（公告）日：2005-11-30

  Catalyst compositions for use in forming polyurethane products include a gelling catalyst, a trimerization catalyst, and a cure accelerator. The gelling catalyst is a tertiary amine, mono(tertiary amino) urea, bis(tertiary amino) urea, or a combination of any of these. Any known trimerization catalyst may be used. The cure accelerator may be a diol having at least one primary hydroxyl group, and having from five to 17 chain backbone atoms chosen from carbon, oxygen, or both between the hydroxyl groups, provided that at least five of the backbone atoms are carbon. Alternatively or in addition, the cure accelerator may be a polyol having three or more hydroxyl groups, at least two of which are primary, and having molecular weights between 90 g/mole and 400 g/mole. Delayed initiation of the polyurethane-forming reaction and/or reduced demold time for producing the polyurethane part can be obtained by using these catalyst compositions.

  用于形成聚氨酯产品的催化剂组合物包括胶凝催化剂、三聚催化剂和固化促进剂。胶凝催化剂是一种叔胺、单（叔氨基）脲、双（叔氨基）脲或其中任何一种的组合。也可使用任何已知的三聚催化剂。固化促进剂可以是具有至少一个伯羟基的二元醇，在羟基之间具有 5 至 17 个碳原子、氧原子或两者兼有的链骨架原子，但至少有五个骨架原子是碳原子。另外，固化促进剂可以是具有三个或三个以上羟基（其中至少两个是伯羟基）的多元醇，分子量在 90 克/摩尔到 400 克/摩尔之间。使用这些催化剂组合物可以延迟聚氨酯成型反应的开始时间和/或缩短生产聚氨酯 部件的脱模时间。
• NOVEL CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME
  申请人：Tosoh Corporation

  公开号：EP2657237A1

  公开（公告）日：2013-10-30

  To provide a novel cyclic amine compound and a process for producing a polyurethane resin by using it. A3-hydroxy-1,5-diazabicyclo[3.2.2]nonane represented by the following formula (1), and a process for producing a polyurethane resin by using a catalyst for producing a polyurethane resin, which contains the 3-hydroxy-1,5-diazabicyclo[3.2.2]nonane. When the compound represented by the formula (1) has optical isomers, diastereomers or geometric isomers, the compound includes both a mixture of any of them and an isolated isomer of any of them. [in the above formula (1), each of R1, R2, R3, R4, R5, R6, R7 and R8 which are independent of one another, is a hydrogen atom, a C1-4 alkyl group, a hydroxy group, a hydroxymethyl group or a C1-4 alkoxy group.]

  提供一种新型环胺化合物和一种使用该化合物生产聚氨酯树脂的工艺。提供一种由下式（1）代表的 A3-羟基-1,5-二氮杂双环[3.2.2]壬烷，以及一种通过使用含有 3-羟基-1,5-二氮杂双环[3.2.2]壬烷的生产聚氨酯树脂的催化剂生产聚氨酯树脂的工艺。当式（1）所代表的化合物具有光学异构体、非对映异构体或几何异构体时，该化合物既包括其中任一异构体的混合物，也包括其中任一异构体的分离异构体。 [在上式（1）中，相互独立的 R1、R2、R3、R4、R5、R6、R7 和 R8 各为氢原子、C1-4 烷基、羟基、羟甲基或 C1-4 烷氧基。］