N-phenylpropiolyl salicylhydrazide | 960251-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenylpropiolyl salicylhydrazide
• 英文别名: 2-hydroxy-N'-(3-phenylprop-2-ynoyl)benzohydrazide
• CAS: 960251-99-4
• 化学式: C₁₆H₁₂N₂O₃
• 分子量: 280.283
• InChiKey: VCOIXQQAGBYJSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.4
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N,N-二甲基甲酰胺 、 manganese (II) acetate tetrahydrate 、 N-phenylpropiolyl salicylhydrazide 在 O₂ 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 [Mn15(N-phenylpropiolyl salicylhydrazide(-3H))15(H2O)9(DMF)6]
  参考文献：
  名称：

  A Chiral Pentadecanuclear Metallamacrocycle with a Sextuple Twisted Möbius Topology

  摘要：

  A C (3) symmetric pentadecanuclear metallamacrocycle was obtained by the self-assembly of a pentadentate bridging ligand, N -phenylpropiolyl salicylhydrazide (H3L), and a manganese ion. The combination of a narrow C alpha-C beta region near the bridging domain and a bulky phenyl end away from the bridging domain as a steric domain induced clockwise twists in the cycle. The resulting macrocycle with a sextuple twisted Mobius topology was stabilized by extensive weak intramolecular interactions.

  DOI：

  10.1021/ja075945w
• 作为产物：
  描述：

  水杨酰肼 、 苯丙炔酸 在 三甲基乙酰氯 、 三乙胺 作用下， 以 氯仿 为溶剂， 反应 4.5h， 以76.5%的产率得到N-phenylpropiolyl salicylhydrazide
  参考文献：
  名称：

  A Chiral Pentadecanuclear Metallamacrocycle with a Sextuple Twisted Möbius Topology

  摘要：

  A C (3) symmetric pentadecanuclear metallamacrocycle was obtained by the self-assembly of a pentadentate bridging ligand, N -phenylpropiolyl salicylhydrazide (H3L), and a manganese ion. The combination of a narrow C alpha-C beta region near the bridging domain and a bulky phenyl end away from the bridging domain as a steric domain induced clockwise twists in the cycle. The resulting macrocycle with a sextuple twisted Mobius topology was stabilized by extensive weak intramolecular interactions.

  DOI：

  10.1021/ja075945w

文献信息

• A Chiral Pentadecanuclear Metallamacrocycle with a Sextuple Twisted Möbius Topology
  作者：Rohith P. John、Mira Park、Dohyun Moon、Kyungjin Lee、Seunghee Hong、Yang Zou、Chang Seop Hong、Myoung Soo Lah

  DOI：10.1021/ja075945w

  日期：2007.11.1

  A C (3) symmetric pentadecanuclear metallamacrocycle was obtained by the self-assembly of a pentadentate bridging ligand, N -phenylpropiolyl salicylhydrazide (H3L), and a manganese ion. The combination of a narrow C alpha-C beta region near the bridging domain and a bulky phenyl end away from the bridging domain as a steric domain induced clockwise twists in the cycle. The resulting macrocycle with a sextuple twisted Mobius topology was stabilized by extensive weak intramolecular interactions.