But-3-enoic acid cyclohexyl ester | 23163-04-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: But-3-enoic acid cyclohexyl ester
• 英文别名: Cyclohexyl but-3-enoate
• CAS: 23163-04-4
• 化学式: C₁₀H₁₆O₂
• 分子量: 168.236
• InChiKey: UCGBCBREJOVVSC-UHFFFAOYSA-N

物化性质

• 沸点：
  223.7±9.0 °C(Predicted)
• 密度：
  0.96±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  But-3-enoic acid cyclohexyl ester 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 168.0h， 生成 cyclohexyl 3,4-epoxybutanoate
  参考文献：
  名称：

  Lipase-catalyzed resolution of esters of 4-chloro-3-hydroxybutanoic acid: effects of the alkoxy group and solvent on the enantiomeric ratio

  摘要：

  Various lipases have been investigated for their potential use as catalysts for the resolution of esters of 4-chloro-3-hydroxybutanoic acid via transesterification in organic solvents. Rhizomucor miehei lipase was found to be the most efficient lipase, with the enantiomeric ratio (E) being dependent upon of the nature of the alkoxy group of the ester and the resolution medium. Higher E-values were obtained when transesterification was performed in benzene or carbon tetrachloride than was the case in hexane. In mixtures of benzene and hexane the trend in E-values followed a linear relationship. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00126-3
• 作为产物：
  描述：

  2-丁烯酰氯 、 环己醇 在 三乙胺 作用下， 以 甲苯 、 苯酚 为溶剂， 以88%的产率得到But-3-enoic acid cyclohexyl ester
  参考文献：
  名称：

  一种3-丁烯酸酯的合成方法

  摘要：

  本发明公开了一种3-丁烯酸酯的合成方法，包括如下步骤：步骤一：室温下,按照重量份，加入400-600份甲苯、120-150份三乙胺、110-120份醇，在电动搅拌混合均匀的同时加热至40-60℃，再缓慢加入100份巴豆酰氯，反应过夜,气相色谱检测反应进程；步骤二：反应结束，冷却反应液，液体用水洗涤两次，无水硫酸镁干燥，过滤，旋转蒸发除甲苯溶剂，得到3-丁烯酸酯粗品；步骤三：将步骤二得到的3-丁烯己酸酯粗品进行后处理得到产品3-丁烯酸酯。本发明的有益效果：本发明合成的3-丁烯酸酯的方法具有产物收率高，副产物少，反应时间短，绿色环保，催化剂利用率高等特点。

  公开号：

  CN106748786A

文献信息

• Intermolecular oxidative amination of unactivated alkenes by dual photoredox and copper catalysis
  作者：Xiangli Yi、Xile Hu

  DOI：10.1039/d0sc05952h

  日期：——

  photochemical generation of amidyl radicals with Cu-mediated β-H elimination of alkyl radicals, we have developed an intermolecular oxidative amination of unactivated alkenes. The reaction relies on tandem photoredox and copper catalysis, and works for both terminal and internal alkenes. The radical nature of the reaction and the mild conditions lead to high functional group tolerance.

  通过酰胺基自由基加成对烯烃的氧化胺化可能是产生烯丙基胺的有效方法，烯丙基胺是生物活性化合物和有机材料的通用合成中间体。在这里，通过将酰胺基的光化学生成与铜介导的烷基的β-H消除相结合，我们开发了未活化烯烃的分子间氧化胺化。该反应依赖于串联的光氧化还原和铜催化，并且适用于末端烯烃和内部烯烃。反应的自由基性质和温和条件导致较高的官能团耐受性。
• Nickel-Catalyzed Regio- and Enantioselective Hydroamination of Unactivated Alkenes Using Carbonyl Directing Groups
  作者：Changseok Lee、Hyung-Joon Kang、Huiyeong Seo、Sungwoo Hong

  DOI：10.1021/jacs.2c02343

  日期：2022.5.25

  addition of an N–H bond to various alkenes via a direct catalytic method is a powerful way of synthesizing value-added chiral amines. Therefore, the enantio- and regioselective hydroamination of unactivated alkenes remains an appealing goal. Here, we report the highly enantio- and regioselective Ni-catalyzed hydroamination of readily available unactivated alkenes bearing weakly coordinating native

  通过直接催化方法将 N-H 键不对称加成到各种烯烃上是合成高附加值手性胺的有效方法。因此，未活化烯烃的对映选择性和区域选择性加氢胺化仍然是一个有吸引力的目标。在这里，我们报告了具有弱配位天然酰胺或酯的现成未活化烯烃的高度对映选择性和区域选择性 Ni 催化的加氢胺化。该方法对末端和内部未活化烯烃均适用，并且具有广泛的胺偶联伙伴范围。温和的反应过程非常适合复杂分子的后期功能化，并有可能获得对映体富集的 β- 或 γ- 氨基酸衍生物和 1,2- 或 1,3-二胺的模块化访问。
• Process for preparing linear monofunctional and telechelic difunctional polymers and compositions obtained thereby
  申请人：AMOCO CORPORATION

  公开号：EP0626402A2

  公开（公告）日：1994-11-30

  This invention relates to a process for preparation of non-crosslinked linear monofunctional and telechelic difunctional unsaturated polymers wherein the functional groups are reactive terminal groups other than vinyl groups. The average functionality number of the monofunctional unsaturated polymers is at least 0.7, as determined by nuclear magnetic resonance spectroscopy (NMR). The average functionality number of the telechelic difunctional polymers is at least 1.6-1.7, as determined by NMR. Monofunctional olefins and difunctional olefins are reacted with cyclic olefins or unsaturated polymers to prepare difunctional polymers. The process is substantially free of side reactions comprising double bond migration and cyclization. The unsaturated functional polymers can be reacted in condensation, addition and transesterification reactions to prepare polyesters, graft copolymers, polyurethanes, polyureas, polyamides, thermoplastic and thermosetting resins, block copolymers, ion exchange resins, adhesives, films, fibers, foams and flocculants.

  本发明涉及一种非交联线性单官能团和远志双官能团不饱和聚合物的制备工艺，其中的官能团是乙烯基以外的活性末端基团。通过核磁共振光谱（NMR）测定，单官能团不饱和聚合物的平均官能度数至少为 0.7。通过核磁共振光谱测定，双官能团聚合物的平均官能度数至少为 1.6-1.7。单官能烯烃和双官能烯烃与环状烯烃或不饱和聚合物反应制备双官能聚合物。该工艺基本上不存在包括双键迁移和环化在内的副反应。不饱和官能团聚合物可通过缩合、加成和酯交换反应制备聚酯、接枝共聚物、聚氨酯、聚氨酯、聚酰胺、热塑性和热固性树脂、嵌段共聚物、离子交换树脂、粘合剂、薄膜、纤维、泡沫和凝聚剂。
• Acrylic resin composition
  申请人：Kawamura Akira

  公开号：US20050244657A1

  公开（公告）日：2005-11-03

  An acrylic resin composition comprising the following acrylic resins (1) and (2): acrylic resin (1): an acrylic resin containing a structural unit derived from a monomer (a) (structural unit (a)) and a structural unit derived from a monomer (b) (structural unit (b)); acrylic resin (2): an acrylic resin having a molecular weight of 1,100,000 to 1,500,000, and containing the structural unit (a) as the main component and a structural unit derived from a monomer (c) (structural unit (c)) and substantially not containing the structural unit (b); (a): a (meth)acrylate of the formula (A) (wherein, R 1 represents a hydrogen atom or methyl group, R 2 represents an alkyl group having 1 to 14 carbon atoms or an aralkyl group having 1 to 14 carbon atoms, and a hydrogen atom in the alkyl group R 2 or a hydrogen atom in the aralkyl group R 2 may be substituted with an alkoxy group having 1 to 10 carbon atoms.), (b): a monomer containing an olefinic double bond in the molecule and at least one 5- or more-membered heterocyclic group in the molecule, (c): a monomer not containing 5- or more-membered heterocyclic group and containing one olefinic double bond and at least one polar functional group selected from the group consisting of a carboxyl group, hydroxyl group, amide group, amino group, epoxy group, oxetanyl group, aldehyde group and isocyanate group in the molecule.

  一种丙烯酸树脂组合物，由以下丙烯酸树脂 (1) 和 (2) 组成：丙烯酸树脂 (1)：一种丙烯酸树脂，含有源自单体 (a) 的结构单元（结构单元 (a)）和源自单体 (b) 的结构单元（结构单元 (b)）；丙烯酸树脂 (2)：分子量在 1,100,000 至 1,500,000 之间的丙烯酸树脂，其主要成分含有结构单元 (a)和由单体(c)衍生的结构单元（结构单元 (c)），且基本上不含结构单元 (b)； (a) 式(A)的(甲基)丙烯酸酯 (其中，R 1 代表氢原子或甲基，R 2 代表具有 1 至 14 个碳原子的烷基或具有 1 至 14 个碳原子的芳烷基，烷基中的氢原子 R 2 中的一个氢原子或烷基基团 R 2 可被具有 1 至 10 个碳原子的烷氧基取代）、 (b) 分子中含有一个烯烃双键和至少一个五元或五元以上杂环基团的单体， (c) 分子中不含有五元或五元以上杂环基团，但含有一个烯烃双键和至少一个极性官能团的单体，该极性官能团选自羧基、羟基、酰胺基、氨基、环氧基、氧杂环丁烷基、醛基和异氰酸酯基。
• Adhesive
  申请人：Takeko Ryu

  公开号：US20060036040A1

  公开（公告）日：2006-02-16

  An adhesive obtained by compounding a cross-linking agent to an acrylic resin composition comprising a silane-based compound and the following acrylic resins (1) and (2), wherein the content of acrylic resin (1) is 10 to 50 parts by weight based on 100 parts by weight of the total amount of the acrylic resin (1) and acrylic resin (2); acrylic resin (1): an acrylic resin having a molecular weight of 50,000 to 500,000 and containing a structural unit derived from a monomer (a) (structural unit (a)); acrylic resin (2): an acrylic resin having a molecular weight of 1,000,000 to 1,500,000 and a molecular weight distribution (Mw/Mn) of 5 or less, and containing the structural unit (a) as the main component and a structural unit derived from a monomer (b) (structural unit (b)); (a): a (meth)acrylate of the formula (A) (b): a monomer containing one olefinic double bond and at least one polar functional group selected from the group consisting of a carboxyl group, hydroxyl group, amide group, amino group, epoxy group, oxetanyl group, aldehyde group and isocyanate group in the molecule.

  一种通过将交联剂与丙烯酸树脂组合物复合而获得的粘合剂，该丙烯酸树脂组合物包括硅烷基化合物和以下丙烯酸树脂(1)和(2)，其中丙烯酸树脂(1)的含量以丙烯酸树脂(1)和丙烯酸树脂(2)总量的 100 重量份计为 10 至 50 重量份；丙烯酸树脂(1)：丙烯酸树脂 (2)：分子量为 1,000,000 至 1,500,000 且分子量分布 (Mw/Mn) 为 5 或以下的丙烯酸树脂，包含作为主要成分的结构单元 (a) 和衍生自单体 (b) 的结构单元 (结构单元 (b))； (a) 式（A）的（甲基）丙烯酸酯 (b): 分子中含有一个烯烃双键和至少一个极性官能团的单体，该极性官能团选 自羧基、羟基、酰胺基、氨基、环氧基、氧杂环丁烷基、醛基和异氰酸酯基。