2-(3,4-dihydroxyphenyl)-8-[(4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(3,4-dihydroxyphenyl)-8-[(4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
• 化学式: C₃₀H₂₆O₁₂
• 分子量: 578.5
• InChiKey: XFZJEEAOWLFHDH-DAIQQCIXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  42
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  221
• 氢给体数：
  10
• 氢受体数：
  12

文献信息

• Treatment of inflammation
  申请人：Kealey Kirk S.

  公开号：US20080188550A1

  公开（公告）日：2008-08-07

  This invention relates to methods of treating inflammation comprising administering to a subject in need thereof a composition comprising the inventive compounds described herein.
• Epicatechin and vasodilation
  申请人：Kealey Kirk S.

  公开号：US20090069414A1

  公开（公告）日：2009-03-12

  This invention relates to compositions comprising epicatechin and method of use of such compositions for inducing vasodilation of blood vessels in humans and veterinary animals.
• Treatment of periodontal disease
  申请人：Kealey Kirk S.

  公开号：US20090117072A1

  公开（公告）日：2009-05-07

  This invention relates to a method of therapeutic or prophylactic treatment of periodontal disease comprising administering to a subject in need thereof epicatechin and/or catechin and/or a polymeric compound of formula A n . Also disclosed and claimed is an article of manufacture comprising the above compounds packaged within a container with instructions for use thereof.
• PROCESS FOR OBTAINING A TANNIN EXTRACT ISOLATED FROM GRAPES, TANNIN EXTRACT OBTAINED AND USES THEREOF
  申请人：UNIVERSITAT DE LLEIDA

  公开号：US20200121752A1

  公开（公告）日：2020-04-23

  A process is provided for obtaining a tannin extract isolated from grapes using grape seeds. The process comprises: preparing the grape seeds as the source of tannins; preparing an aqueous solution of a polyphenol-solubilising agent selected from urea, a compound containing the SO 3 group and sodium hydroxide at concentration ranging between 1% and 15% by weight; performing a single extraction in an autoclave reactor; separation and direct concentration in order to produce the isolated extract. The invention also relates to the tannin extract obtained. The new tannin extract isolated from grape seeds comprises a mixture of tannins and non-tannins, the composition whereof provides the extract with improved antioxidant and light fastness properties. The tannin extract isolated from grape seeds further comprises a colouring agent.
• US7754760B2
  申请人：——

  公开号：US7754760B2

  公开（公告）日：2010-07-13