5,7,4'-Trihydroxy-6-methyl-8-prenylflavanone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5,7,4'-Trihydroxy-6-methyl-8-prenylflavanone
• 英文别名: (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methyl-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
• 化学式: C₂₁H₂₂O₅
• 分子量: 354.4
• InChiKey: MWEMUFLDDBSWRI-KRWDZBQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• US6136849A
  申请人：——

  公开号：US6136849A

  公开（公告）日：2000-10-24
• [EN] ANTIBACTERIAL AND ANTIFUNGAL FLAVANONES FROM EYSENHARDTIA TEXANA<br/>[FR] FLAVANONES A EFFET ANTIBACTERIEN ET ANTIFONGIQUE PROVENANT DE L'EYSENHARDTIA TEXANA
  申请人：RES DEV FOUNDATION

  公开号：WO2000020406A1

  公开（公告）日：2000-04-13

  An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana Kunth. (Fabaceae) led to the isolation of two new antibacterial and antifungal flavanones. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra. These compounds have potent antibacterial and antifungal activity as measured by bioassay.