聚乙二醇乙二酯 | 79793-05-8

• 物质功能分类: 催化剂及助剂 - 聚乙二醇衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 聚乙二醇乙二酯
• 中文别名: α-(2-乙基-1-氧代己基)-ω-(2-乙基-1-氧代己基氧)聚氧乙烯
• 英文名称: Glycol diethylhexanoate
• 英文别名: 2-(2-ethylhexanoyloxy)ethyl 2-ethylhexanoate
• CAS: 79793-05-8；9004-93-7
• 化学式: C₁₈H₃₄O₄
• 分子量: 314.5
• InChiKey: XCQFTFZCTGZCNP-UHFFFAOYSA-N

物化性质

• 熔点：
  -48 °C (lit.)
• 沸点：
  255 °C(Press: 5 Torr)
• 密度：
  1.02 g/mL at 25 °C (lit.)
• 闪点：
  >230 °F
• 溶解度：
  不溶于水

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  22
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] METHOD OF PREPARING GLYCOL ESTERS WITH LOW COLOR AND PEROXIDE CONTENT<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ESTERS DE GLYCOL À FAIBLE TENEUR EN COULEUR ET EN PEROXYDE
  申请人：SIBUR HOLDING PUBLIC JOINT STOCK CO

  公开号：WO2019059800A1

  公开（公告）日：2019-03-28

  The present invention relates to the field of preparing glycol esters used as plasticizers in the manufacture of films for multilayered glass. In particular, the invention relates to a method for preparing triethylene glycol ester of 2-ethylhexanoic acid. The claimed method includes the steps of esterification, clarification of a crude ester by treating thereof with hydrogen peroxide and alkali metal metasilicate at a temperature of from 70 to 200ºC, inclusive, and allowing to stand for 0.5 to 1.5 hours, inclusive, to obtain a clarified ester, neutralization of acidic compounds in the clarified ester by treating thereof with an alkaline solution, filtration, and drying of the ester. The technical result of the invention is the development of an economical and safe method of preparing glycol esters that are characterized by low values of color, acidity and peroxide content.

  本发明涉及制备用作多层玻璃薄膜制造中的增塑剂的乙二醇酯的领域。具体而言，该发明涉及一种制备2-乙基己酸三乙二醇酯的方法。所述方法包括酯化、通过在70至200ºC的温度下用过氧化氢和硅酸碱金属处理粗酯以澄清粗酯，并静置0.5至1.5小时以获得澄清酯，通过用碱性溶液处理澄清酯中的酸性化合物进行中和，过滤和干燥酯。该发明的技术效果是开发一种经济且安全的制备乙二醇酯的方法，其特点是颜色、酸度和过氧化物含量低。
• [EN] SYNTHESIS OF TRIETHYLENE GLYCOL BIS(2-ETHYLHEXANOATE)<br/>[FR] SYNTHÈSE DE TRIÉTHYLÈNE GLYCOL BIS(2-ÉTHYLHEXANOATE)
  申请人：EASTMAN CHEM CO

  公开号：WO2020102128A1

  公开（公告）日：2020-05-22

  A process for the transesterification of methyl-2- ethylhexanoate with triethylene glycol to produce triethylene glycol di-2-ethylhexanoate is provided. In the process, methyl-2- ethylhexanoate is combined with triethylene glycol to form a first mixture. The first mixture is heated in the presence of a catalyst to form a second mixture comprising methanol and triethylene glycol di-2-ethylhexanoate. Methanol is separated from the second mixture to yield triethylene glycol di-2-ethylhexanoate. Na2CO3, CS2CO3, K2CO3, Rb2CO3, sodium methoxide or titanium isopropoxide are suitable catalysts.

  提供了一种用三乙二醇对甲基-2-乙基己酸酯进行酯交换反应以产生三乙二醇二-2-乙基己酸酯的方法。在该过程中，将甲基-2-乙基己酸酯与三乙二醇混合形成第一混合物。在催化剂的存在下加热第一混合物，形成包含甲醇和三乙二醇二-2-乙基己酸酯的第二混合物。将甲醇从第二混合物中分离出来，得到三乙二醇二-2-乙基己酸酯。Na2CO3、CS2CO3、K2CO3、Rb2CO3、甲基钠或异丙酸钛是适合的催化剂。
• MELANIN PRODUCTION INHIBITOR
  申请人：Yokoyama Kouji

  公开号：US20110243865A1

  公开（公告）日：2011-10-06

  Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent, wherein at least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group, wherein when one of R1 and R2 is an oxo group, the other is not present; and R3 is selected from a hydrogen atom, and a C 1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms, wherein the number of R3's present in the compound corresponds to the number of X's and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.

  披露了一种黑色素生产抑制剂，它对黑色素的生产具有出色的抑制活性且高度安全。该黑色素生产抑制剂包括由通用公式（1）表示的化合物（不包括克霉唑）和/或其药理上可接受的盐。在公式中，A1、A2和A3独立地选自氢原子、可能带有取代基的芳基团和可能带有取代基的芳香杂环团，其中至少A1、A2和A3之一选自芳基团和芳香杂环团，A1、A2和A3中包含的碳原子总数为6至50，并且当至少两个A1、A2和A3表示芳基团或芳香杂环团时，相邻的两个芳基或芳香杂环团可以通过烷基链或烯基链相互连接形成环；m代表0至2的整数；X代表异原子、氢原子或碳原子；R1和R2独立地选自氢原子和氧代基，其中当R1和R2之一是氧代基时，另一个不出现；R3选自氢原子和C 1-8 碳氢化合物组，其中一些或所有的氢原子或碳原子可能被异原子或异原子取代，其中化合物中存在的R3的数量对应于X的数量，并且当存在两个或更多R3时，R3独立地存在，并且相邻的两个R3可以相互连接以与X一起形成环，并且R3的末端可以与A1、A2和A3连接的碳原子结合，从而形成环。
• OIL-IN-WATER EMULSION COSMETIC COMPOSITION
  申请人：Dow Toray Co., Ltd.

  公开号：US20210330559A1

  公开（公告）日：2021-10-28

  An oil-in-water emulsion cosmetic composition is provided. The oil-in-water emulsion cosmetic composition comprises a carboxylic acid modified silicone (A) that has a specific chemical structure and is liquid at room temperature, an oil agent (B), and water (C). The oil-in-water emulsion cosmetic composition can provide a cosmetic film with high stability and excellent water resistance.

  提供了一种油包水乳化化妆品组合物。该油包水乳化化妆品组合物包括一种在室温下为液体的具有特定化学结构的羧酸改性硅氧烷（A）、一种油剂（B）和水（C）。该油包水乳化化妆品组合物可以提供具有高稳定性和优异耐水性的化妆膜。
• NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20170137574A1

  公开（公告）日：2017-05-18

  The present invention provides a silicone compound shown by the formula (1) and having a weight-average molecular weight in the range of 500 to 200,000, R 1 a R 2 b R 3 c R 4 d SiO (4-a-b-c-d)/2 (1), wherein R 1 represents the same or different organic group, R 2 represents a polyoxyalkylene group shown by —C m H 2m —O—(C 2 H 4 O) g (C 3 H 6 O) h R 6 , R 3 represents a branched type monovalent organosiloxane group shown by the following general formula (4), M o M R p D q D R r T s T R t Q u (4), and R 4 represents a monovalent organosiloxane group shown by the following general formula (5) or the general formula (6), MM R D v-1 (5), M w D v-1 D R v-2 T R v-3 (6). This provides a silicone compound which has excellent emulsification ability and emulsion stability to silicone oil, and can secure high temporal stability.

  本发明提供了一种硅化合物，其化学式为（1），其重均分子量在500至200,000范围内，R1aR2bR3cR4dSiO(4-a-b-c-d)/2(1)，其中R1代表相同或不同的有机基团，R2代表由—CmH2m—O—(C2H4O)g(C3H6O)hR6表示的聚氧烷基团，R3代表由以下一般式（4）表示的分支型一价有机硅氧烷基团，MoMRpDqDRrTsTRtQu(4)，R4代表由以下一般式（5）或一般式（6）表示的一价有机硅氧烷基团，MMRDv-1(5)，MwDv-1DRv-2TRv-3(6)。这提供了一种硅化合物，具有优异的乳化能力和对硅油的乳液稳定性，并且可以确保高时间稳定性。