2-Pyridin-3-yl-1,3-thiazole-4-carboxamide, N-hydroxy-

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-Pyridin-3-yl-1,3-thiazole-4-carboxamide, N-hydroxy-
• 英文别名: N-hydroxy-2-pyridin-3-yl-1,3-thiazole-4-carboxamide
• 化学式: C₉H₇N₃O₂S
• 分子量: 221.24
• InChiKey: XXMNXKFDTRMRKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  103
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• HDAC6-ACTIVATED MACROPHAGES, COMPOSITIONS, AND USES THEREOF
  申请人：The George Washington University, A Congressionally Chartered Not-for-Profit Corporation

  公开号：US20220401474A1

  公开（公告）日：2022-12-22

  The present disclosure provides histone deacetylase 6 (HDAC6)-activated macrophages, compositions comprising HDAC6-activated macrophages, methods of making HDAC6-activated macrophages, and methods of treating diseases, e.g., cancer, by administering a therapeutically effective amount of HDAC6-activated macrophages.