1,5-diphenyl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester | 53423-23-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,5-diphenyl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester
• 英文别名: 1,5-Diphenyl-1H-[1,2,4]triazol-3-carbonsaeure-aethylester；ethyl 1,5-diphenyl-1H-1,2,4-triazole-3-carboxylate；ethyl 1,5-diphenyl-1,2,4-triazole-3-carboxylate
• CAS: 53423-23-7
• 化学式: C₁₇H₁₅N₃O₂
• mdl: MFCD00838107
• 分子量: 293.325
• InChiKey: MTGWUPSAYQIYMH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  57
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  苯甲酸酐 生成 1,5-diphenyl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester
  参考文献：
  名称：

  LOHER, HEINZ JOSEF;HEUBACH, GUNTHER;BAUER, KLAUS;BIERINGER, HERMANN

  摘要：

  DOI：

文献信息

• OPIOID RECEPTOR SUBTYPE-SELECTIVE AGENTS
  申请人：Welsh William J.

  公开号：US20090181998A1

  公开（公告）日：2009-07-16

  Opioid receptor compounds and pharmaceutical compositions thereof are presented. Also presented are methods for treating a condition mediated by an opioid receptor by administering an effective amount of the opioid receptor compound to a patient in need thereof.
• Methods and Compositions for the Treatment of RAS Associated Disorders
  申请人：Ratner Nancy

  公开号：US20120302581A1

  公开（公告）日：2012-11-29

  The instant disclosure relates to compositions that may be useful as therapeutic agents for the treatment of disorders associated or caused by Ras deregulation or dysregulation, for example, disorders associated with alterations in the NF1 gene such as neurofibromatosis type I, fungal infections such as those caused by Candida albicans , and proliferative disorders such as glioblastoma.
• US8188128B2
  申请人：——

  公开号：US8188128B2

  公开（公告）日：2012-05-29