N-[4-(1-methylimidazol-4-yl)phenyl]acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-[4-(1-methylimidazol-4-yl)phenyl]acetamide
• 化学式: C₁₂H₁₃N₃O
• 分子量: 215.25
• InChiKey: AKWRAPSEKVAVDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions
  申请人：Trieselmann Thomas

  公开号：US20080234278A1

  公开（公告）日：2008-09-25

  The present invention relates to new beta-agonists of general formula (I) wherein the groups R 1 to R 7 have the meanings given in the claims and specification, the tautomers, the enantiomers, the diastereomers, the mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, processes for preparing these compounds and their use as pharmaceutical compositions.

  本发明涉及通式（I）的新型β-激动剂，其中R1至R7的基团具有权利要求书和说明书中所给出的含义，它们的互变异构体、对映异构体、顺反异构体、混合物、前药及其盐，特别是与无机或有机酸或碱的生理上可接受的盐，制备这些化合物的过程以及它们作为药物组成物的用途。
• Use of aminoalcohol derivatives for the treatment of overactive bladder
  申请人：Trieselmann Thomas

  公开号：US20090221589A1

  公开（公告）日：2009-09-03

  The present invention relates to the use of new beta-agonists of general formula (Ia) or (Ib) wherein the groups R 1 to R 12 and R 1 to R 7 , respectively, have the meanings given in the claims and specification, the tautomers, the enantiomers, the diastereomers, the mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, for preparing a medicament for the treatment of overactive bladder.
• US7977334B2
  申请人：——

  公开号：US7977334B2

  公开（公告）日：2011-07-12