N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)-2,2-dimethylpropanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)-2,2-dimethylpropanamide
• 化学式: C₁₆H₂₀N₂OS
• 分子量: 288.4
• InChiKey: YZXRMXNKMCAXQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  70.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Heterocyclic Compounds Which Modulate The CB2 Receptor
  申请人：Bartolozzi Alessandra

  公开号：US20110312944A1

  公开（公告）日：2011-12-22

  Compounds which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  本发明揭示了调节CB2受体的化合物。根据本发明，这些化合物与CB2受体结合并作为激动剂，用于治疗炎症。那些作为激动剂的化合物还可用于治疗疼痛。
• Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor
  申请人：Hickey Eugene Richard

  公开号：US20120142666A1

  公开（公告）日：2012-06-07

  Compounds of the formula (I), (II) and (III) which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  公式（I），（II）和（III）的化合物被揭示，这些化合物可以调节CB2受体。本发明的化合物结合并是CB2受体的激动剂，可用于治疗炎症。那些是激动剂的化合物还可用于治疗疼痛。
• Compounds Which Modulate The CB2 Receptor
  申请人：Berry Angela

  公开号：US20100331304A1

  公开（公告）日：2010-12-30

  Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  公式（I）的化合物被披露。本发明的化合物与CB2受体结合并具有激动剂作用，可用于治疗炎症。那些具有激动剂作用的化合物还可用于治疗疼痛。
• US8383615B2
  申请人：——

  公开号：US8383615B2

  公开（公告）日：2013-02-26
• US8546563B2
  申请人：——

  公开号：US8546563B2

  公开（公告）日：2013-10-01