(S)-(-)-sodium 2-hydroxy-4-methylpentanoate | 54641-21-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (S)-(-)-sodium 2-hydroxy-4-methylpentanoate
• 英文别名: L-α-Hydroxy-isocapronsaeure-Na-salz；(S)-2-hydroxy-4-methyl-valeric acid ; sodium-salt；(S)-2-Hydroxy-4-methyl-valeriansaeure; Natrium-Salz；2-Hydroxy-4-methyl-valeriansaeure; Natriumsalz；Sodium (S)-2-hydroxy-4-methylvalerate；sodium;(2S)-2-hydroxy-4-methylpentanoate
• CAS: 54641-21-3
• 化学式: C₆H₁₁O₃*Na
• 分子量: 154.141
• InChiKey: WMPVOYIJOLKBNA-JEDNCBNOSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.85
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  60.4
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2918199090

反应信息

• 作为反应物：
  描述：

  (S)-(-)-sodium 2-hydroxy-4-methylpentanoate 在 4-吡咯烷基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 30.0h， 生成 (S)-1-(benzyloxycarbonyl)-3-methylbuthyl 4'-octocxybiphenyl-4-carboxylate
  参考文献：
  名称：

  Chan, L. K. M.; Gray, G. W.; Lacey, D., Molecular Crystals and Liquid Crystals (1969-1991), 1989, vol. 172, p. 125 - 146

  摘要：

  DOI：
• 作为产物：
  描述：

  L-亮氨酸 在 sodium hydroxide 、 硫酸 、 sodium nitrite 作用下， 生成 (S)-(-)-sodium 2-hydroxy-4-methylpentanoate
  参考文献：
  名称：

  Chan, L. K. M.; Gray, G. W.; Lacey, D., Molecular Crystals and Liquid Crystals (1969-1991), 1989, vol. 172, p. 125 - 146

  摘要：

  DOI：

文献信息

• [EN] PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA)<br/>[FR] PRÉPARATIONS CONTENANT UNE PYRIDOXINE ET UN ACIDE ALPHA-HYDROXYIOSCAPROÏQUE (HICA)
  申请人：IOVATE T & P INC

  公开号：WO2009073943A1

  公开（公告）日：2009-06-18

  The present invention relates to stable salts of pyridoxine and α-hydroxyisocaproic acid (HICA) endowed with enhanced nutritional and/or therapeutical efficacy in respect to their individual effects and to solid compositions containing such salts, particularly suited to oral administration. A method of preparation is also provided.

  本发明涉及稳定的吡ridoxine和α-羟基异戊酸（HICA）盐，具有增强的营养和/或治疗功效，相对于它们各自的效果，以及含有这种盐的固体组合物，特别适用于口服。同时提供了一种制备方法。
• Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA)
  申请人：Molino Michele

  公开号：US20090156648A1

  公开（公告）日：2009-06-18

  The present invention relates to stable salts of pyridoxine and α-hydroxyisocaproic acid (HICA) endowed with enhanced nutritional and/or therapeutical efficacy in respect to their individual effects and to solid compositions containing such salts, particularly suited to oral administration. A method of preparation is also provided.

  本发明涉及稳定的吡ridoxine和α-羟基异戊酸（HICA）盐，具有增强的营养和/或治疗功效，相对于它们各自的效果，并涉及含有这种盐的固体组合物，特别适用于口服给药。还提供了一种制备方法。
• COMPOSITION AND METHOD FOR INCREASING THE ANABOLIC STATE OF MUSCLE CELLS
  申请人：Northern Innovations And Formulations Corp.

  公开号：EP2192898A1

  公开（公告）日：2010-06-09
• PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA)
  申请人：Northern Innovations and Formulations Corp.

  公开号：EP2231604A1

  公开（公告）日：2010-09-29
• Method for maintaining physiological pH levels during intensive physical exercise
  申请人：Molino Michele

  公开号：US20090156647A1

  公开（公告）日：2009-06-18

  A nutritional supplement comprising at least a therapeutically effective amount of pyridoxine α-hydroxyisocaproate is provided by the present invention. The ingredients of the present nutritional supplement act substantially simultaneously to maintain physiological blood and muscular pH and increase the time to muscular fatigue in a mammal during periods of repetitive forceful muscular exercise. A method of use is provided by the present disclosure.